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Current Issues in Molecular Biology publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue polices and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Protein Hydrolysates: Biological Activity and Applications submission deadline 31 Jan 2025 | 2 articles | Viewed by 4597
Keywords: protein; hydrolysis; hydrolysis constant; inhibitor protein; polymer degradation; proteolysis
(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)
Molecular Insights into Melanogenesis and Melanoma Development
edited by Urszula Kazimierczak
submission deadline 31 Jan 2025 | 1 articles | Viewed by 680
Keywords: melanoma; genetics; genomics; biomarkers; melanoma pathology; RNA; biomarkers and molecular inhibitors
(This special issue belongs to the Section Molecular Medicine)
Biosafety and Biotoxicity of Nanomaterials
edited by
submission deadline 31 Jan 2025 | Viewed by 403
Keywords: nanomaterials; biosafety; biotoxicity; bioaccumulation; biodegradation
(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)
The Role of Natural Compounds in Cancer Therapy
edited by
submission deadline 10 Feb 2025 | 2 articles | Viewed by 1107 | Submission Open
Keywords: natural compounds; cancer; repurposing; combination; polychemotherapy; pharmaceuticals; nutraceuticals; molecular targets; metabolism; metabolomics; enhancing efficacy; immunotherapy
(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)
Editorial Board Members' Collection Series: Natural Product Pharmacology submission deadline 25 Feb 2025 | Viewed by 230 | Submission Open
Keywords: natural compounds; bioactive molecules; molecular mechanisms; therapeutic targets; drug discovery; pharmacokinetics; pharmacodynamics; cellular signaling pathways
(This special issue belongs to the Section Molecular Pharmacology)
The Role of Bioactives in Inflammation
edited by and
submission deadline 28 Feb 2025 | 19 articles | Viewed by 29220 | Submission Open
Keywords: anti-inflammation; bioactives; drug research and development; inflammatory diseases; natural products; signaling; synthesized compounds
(This special issue belongs to the Section Bioorganic Chemistry and Medicinal Chemistry)
The Significance of Transcription Factors, miRNAs, and lncRNAs in Anticancer Drug Development submission deadline 28 Feb 2025 | 13 articles | Viewed by 15562 | Submission Open
Keywords: transcription factors; microRNAs (miRNAs); long non-coding RNAs (lncRNAs); anticancer drugs; cancer; coactivators
(This special issue belongs to the Section Molecular Medicine)
The Protection and Toxic Reactions of Dietary Supplements: Focusing on Molecular Mechanisms and Treatment
edited by Neuman Manuela
submission deadline 28 Feb 2025 | 8 articles | Viewed by 14475 | Submission Open
Keywords: dietary supplements; toxic reactions; protection mechanisms; bioactives; vitamins; minerals; amino acids
(This special issue belongs to the Section Bioorganic Chemistry and Medicinal Chemistry)
New Insight: Enzymes as Targets for Drug Development, 2nd Edition submission deadline 28 Feb 2025 | 5 articles | Viewed by 4758 | Submission Open
Keywords: enzyme kinetics; enzyme– ligand or protein-protein interactions; enzyme inhibitions; enzyme purifications and optimal conditions; enzyme or protein structures; enzyme or protein computational analysis
(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)
The Regulation and Mechanisms of Genomics in Psychiatry
edited by
submission deadline 28 Feb 2025 | 2 articles | Viewed by 3866 | Submission Open
Keywords: psychiatric genetics; GWAS in mental disorders; congenital neural disorders; human neurodevelopment; computational neuroscience
(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)
Linking Genomic Changes with Cancer in the NGS Era, 2nd Edition
edited by Javier Azúa-Romeo and
submission deadline 28 Feb 2025 | 1 articles | Viewed by 1939 | Submission Open
Keywords: next-generation sequencing (NGS); genetic variation; driver gene; functional validation; gene editing; cancer
(This special issue belongs to the Section Bioinformatics and Systems Biology)
Innate Immunity Responds to Virus Infection
edited by Zhenlu Chong
submission deadline 28 Feb 2025 | 1 articles | Viewed by 1879 | Submission Open
Keywords: viral infection; cGAS-STING; RIG-I; toll-like receptors; IFN-I; IFN-III; JAK-STAT pathway; ubiquitination; cellular and molecular studies; animal model
(This special issue belongs to the Section Molecular Microbiology)
Epithelial Cancers: Molecular Mechanisms, Diagnostic Innovations, and Therapeutic Advances
edited by
submission deadline 28 Feb 2025 | 1 articles | Viewed by 1672 | Submission Open
Keywords: epithelial cancers; molecular mechanisms; genetic alterations; epigenetics; tumor microenvironment; epithelial-mesenchymal transition; biomarkers; liquid biopsy; imaging technologies; targeted therapies; immunotherapies; personalized medicine; treatment resistance; cancer recurrence; translational research
(This special issue belongs to the Section Molecular Medicine)
Molecular Insights into Pathogenesis and Targeted Therapy of Gynaecological Cancers
edited by
submission deadline 28 Feb 2025 | 1 articles | Viewed by 1375 | Submission Open
Keywords: ovarian cancers; cervical cancers; endometrial cancers; targeted therapy; molecular markers; immunotherapy
(This special issue belongs to the Section Molecular Medicine)
Wound Healing: Exploring Novel Biomaterials and Compounds in Light of Cellular and Molecular Mechanisms submission deadline 28 Feb 2025 | 1 articles | Viewed by 1268 | Submission Open
Keywords: wound healing; inflammation; translational medicine; wound repair; pro-regenerative
(This special issue belongs to the Section Molecular Medicine)
Molecular Mechanism of Plant Growth, Development and Secondary Metabolism
edited by
submission deadline 28 Feb 2025 | 1 articles | Viewed by 1256 | Submission Open
Keywords: secondary metabolites; plant defense; signaling and adaptation mechanisms; plant development; genetic and epigenetic regulation; plant physiology
(This special issue belongs to the Section Molecular Plant Sciences)
Membrane Transporters and Channels in Health and Diseases submission deadline 28 Feb 2025 | 1 articles | Viewed by 1197 | Submission Open
Keywords: G-protein-coupled receptors; amino acid transporter; citrate transporter; ion channel; membrane protein; immune regulation
(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)
Mental Disorder: Focus on Pathogenesis to Treatment
edited by
submission deadline 28 Feb 2025 | Viewed by 238 | Submission Open
Keywords: mental disorders; neurobiological; oxidative stress; neuroinflammation; gene variants
(This special issue belongs to the Section Molecular Medicine)
The Molecular Basis of Genetic and Epigenetic Changes in Cancer
edited by Su Yon Jung
submission deadline 28 Feb 2025 | Viewed by 186 | Submission Open
Keywords: next-generation sequencing (NGS); genetic variation; epigenome; DNA methylation; biomarkers; gene expression; proteomics; cancer(s); prediction; prevention; screening; prognosis; treatment; infection; COVID-19; interaction with the environment; occupational hazard
(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)
Advances in piRNA Biology and Processing: Mechanisms and Applications
edited by
submission deadline 28 Feb 2025 | Viewed by 168 | Submission Open
Keywords: piRNA; Piwi; transposable elements; epigenetics; genetics; development; cancer
(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)
Molecular and Real-World Evidence Research of Respiratory Diseases and Infections, 2nd Edition
edited by
submission deadline 28 Feb 2025 | Viewed by 143 | Submission Open
Keywords: respiratory diseases; pathogenesis; vaccines; therapies; COVID-19
(This special issue belongs to the Section Molecular Medicine)
The Molecular Basis of Immunotherapy in Cancer Treatment
edited by Hassan Dastsooz
submission deadline 28 Feb 2025 | Viewed by 138 | Submission Open
Keywords: immunotherapy; cancer; CAR-T cell therapy; monoclonal antibodies; immunomodulation; cytokines; immune evasion mechanisms
(This special issue belongs to the Section Molecular Medicine)
Recent Advances in Nanobiotechnology and Nanomedicine submission deadline 28 Feb 2025 | Viewed by 126 | Submission Open
Keywords: bionanotechnology; nanocarriers; cancer; infectious diseases; drug delivery; bioavailability
(This special issue belongs to the Section Bioorganic Chemistry and Medicinal Chemistry)
Bioinformatics Research in Bacterial Genomics, Metagenomics and Metatranscriptomics
edited by
submission deadline 10 Mar 2025 | 6 articles | Viewed by 8919 | Submission Open
Keywords: bacterial genomics and functional analysis; genome-wide comparative genomics; bioinformatics methods and tools; metagenomics; metatranscriptomics
(This special issue belongs to the Section Molecular Microbiology)
Genomic Analysis of Common Disease, 2nd Edition
edited by
submission deadline 20 Mar 2025 | 1 articles | Viewed by 600 | Submission Open
Keywords: genomic analysis; microarray analysis; whole exome sequencing; pathogenic mutations; copy number variants; DNA sequence variation; intellectual disability; autism; connective tissue dysplasia
(This special issue belongs to the Section Molecular Medicine)
Molecular Research in Osteoarthritis and Osteoarticular Diseases
edited by
submission deadline 31 Mar 2025 | 5 articles | Viewed by 12466 | Submission Open
Keywords: osteoarthritis; cartilage regeneration; bioinformatics; biomarkers; inflammation; cartilage; metabolic imbalance
(This special issue belongs to the Section Molecular Medicine)
Molecules at Play in Neurological Diseases
edited by
submission deadline 31 Mar 2025 | 6 articles | Viewed by 9599 | Submission Open
Keywords: neurological diseases; neurotransmitters; neuropeptides; neurotrophic factors; genetic and epigenetic elements
(This special issue belongs to the Section Molecular Medicine)
Advances in Molecular Pathogenesis Regulation in Cancer 2024
edited by
submission deadline 31 Mar 2025 | 7 articles | Viewed by 8093 | Submission Open
Keywords: cancer; cancer biology; genetic; epigenetic; tumor microenvironment; molecular biology; immune system; biomarkers; cancer diagnosis; target therapy
(This special issue belongs to the Section Molecular Medicine)
Molecular Mechanisms and Regulation in Allergy and Immune Diseases, Immunodeficiencies, 2nd Edition
edited by
submission deadline 31 Mar 2025 | 2 articles | Viewed by 7860 | Submission Open
Keywords: allergy and hypersensitivity mechanisms; cross-reactivity in allergy; component resolved diagnostic (CRD); immunodeficiencies; experimental research methods in allergology; biochemical properties of allergens
(This special issue belongs to the Section Molecular Medicine)
Metabolic Interactions between the Gut Microbiome and Organism
edited by Sree V. Chintapalli
submission deadline 31 Mar 2025 | 2 articles | Viewed by 5551 | Submission Open
Keywords: microbiota dysbiosis; metabolism; inflammation; gut– brain axis; metabolic interactions
(This special issue belongs to the Section Molecular Microbiology)
Natural Products as Potential Sources of Antidiabetic Compounds, 2nd Edition
edited by
submission deadline 31 Mar 2025 | 4 articles | Viewed by 5538 | Submission Open
Keywords: natural products; natural product derivatives; antidiabetic agents; α -glucosidase inhibitors; amylase inhibitors; PTP1B inhibitors; DPP-4 inhibitors; molecular level; kinetic studies; in vitro studies; in vivo studies; computational methods; mode of action
(This special issue belongs to the Section Bioorganic Chemistry and Medicinal Chemistry)
Molecular Mechanisms in Demyelinating Disorders and Remyelination Strategies of the CNS submission deadline 31 Mar 2025 | 3 articles | Viewed by 4189 | Submission Open
Keywords: demyelination; molecular mechanisms; oligodendrocyte precursor cells; myelinogenesis; dysmyelination; lipid metabolism; microglia and macrophages; experimental autoimmune encephalomyelitis; biomarkers; remyelination
(This special issue belongs to the Section Molecular Medicine)
Molecular Research in Chronic Dermatoses, 2nd Edition submission deadline 31 Mar 2025 | 1 articles | Viewed by 3853 | Submission Open
Keywords: dermatopathology; dermatosurgery; skin biology; molecular biology; genetics; JAK inhibitors; antibodies
(This special issue belongs to the Section Molecular Medicine)
The Role of Neuroinflammation in Neurodegenerative Diseases
edited by
submission deadline 31 Mar 2025 | 2 articles | Viewed by 3601 | Submission Open
Keywords: molecular neuropathology; neuroinflammation; multiple sclerosis; neurodegenerative diseases; dementias
(This special issue belongs to the Section Molecular Medicine)
Network Pharmacology, Multi-targets and Receptor–Receptor Interactions in the CNS submission deadline 31 Mar 2025 | 1 articles | Viewed by 2682 | Submission Open
Keywords: network pharmacology; multi-targets; receptor– receptor interactions; target proteins; drug therapy in CNS; receptors
(This special issue belongs to the Section Molecular Pharmacology)
Molecular Insights and Therapeutic Advances in Hematological Disorders
edited by
submission deadline 31 Mar 2025 | 3 articles | Viewed by 2455 | Submission Open
Keywords: acute leukemia; myeloproliferative neoplasms; lymphoma; multiple myeloma; hemoglobinopathies; hemophilia
(This special issue belongs to the Section Molecular Medicine)
Cancer Biomarkers: Discovery and Applications
edited by
submission deadline 31 Mar 2025 | 1 articles | Viewed by 1380 | Submission Open
Keywords: cancer biomarkers; precision medicine; prevention; prognosis; diagnosis
(This special issue belongs to the Section Molecular Medicine)
Innovative Strategies and Applications for Drug Discovery
edited by
submission deadline 31 Mar 2025 | 1 articles | Viewed by 1235 | Submission Open
Keywords: drug discovery; computational strategies; molecular docking; pharmacophore modeling; molecular dynamics simulations
(This special issue belongs to the Section Molecular Medicine)
Microalga Biotechnology and Applications: Molecular and Cellular Mechanisms
edited by
submission deadline 31 Mar 2025 | Viewed by 292 | Submission Open
Keywords: microalgae; biotechnology; cyanobacteria; chlamydomonas; cellular stress; nutrient limitations; molecular mechanisms; omics technologies
(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)
The Role of the Immune System in the Progression of Chronic Liver Disease
edited by
submission deadline 31 Mar 2025 | Viewed by 219 | Submission Open
Keywords: autoimmune hepatitis; epigenetics; fatty liver; inflammation; liver fibrosis; liver repair; therapeutic targets and interventions; transcriptomics; viral hepatitis
(This special issue belongs to the Section Molecular Medicine)
Insights from Genetics, Epigenetics, and Microbiome Research in Obesity: Integrative Approaches to Understand Metabolic Disorders
edited by Shengping Yang
submission deadline 31 Mar 2025 | Viewed by 197 | Submission Open
Keywords: obesity; epigenetics; microbiom; genetics; bioinformatics
(This special issue belongs to the Section Bioinformatics and Systems Biology)
Unraveling the Molecular Marvels of Heart Repair and Regeneration
edited by
submission deadline 31 Mar 2025 | Viewed by 171 | Submission Open
Keywords: cardiac repair; angiogenesis; heart failure; ischemia; reperfusion; reactive oxygen; cell therapy; exosome therapy; gene therapy; apoptosis; ischemic preconditioning; gene editing
(This special issue belongs to the Section Molecular Medicine)
Novel Drug and Pharmaceutical Designs for Anti-Cancer Therapies
edited by
submission deadline 31 Mar 2025 | Viewed by 167 | Submission Open
Keywords: cancer therapeutics; tumor antigens; vaccine; nanotechnology
(This special issue belongs to the Section Molecular Pharmacology)
Molecular Research on Virus-Related Infectious Disease
edited by Guangcai Duan and
submission deadline 31 Mar 2025 | Viewed by 151 | Submission Open
Keywords: molecular diagnosis of viruses; viral genomics; host– virus interactions; molecular pathways; therapeutic targets; vaccine development
(This special issue belongs to the Section Molecular Microbiology)
Exploring RNA Biology and G-Quadruplex Structures: From Mechanisms to Applications
edited by Honghe Liu
submission deadline 31 Mar 2025 | Viewed by 135 | Submission Open
Keywords: RNA G-quadruplex; RNA secondary structures; gene expression regulation; RNA metabolism; therapeutic targets; structural biology; biotechnology applications
(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)
Integrating Bioinformatics and Drug Discovery: Innovations and Applications
edited by Jianwen Fang
submission deadline 31 Mar 2025 | Viewed by 117 | Submission Open
Keywords: bioinformatics; drug discovery; target proteins; drug therapy; receptor– receptor interactions; protein dynamics; structural bioinformatics; computational approaches
(This special issue belongs to the Section Bioinformatics and Systems Biology)
Mechanisms and Pathophysiology of Obesity
edited by Padmamalini Baskaran
submission deadline 31 Mar 2025 | Viewed by 115 | Submission Open
Keywords: understanding genetic factors for obesity at the molecular level; understanding environmental factors for obesity at the molecular level; contribution of insulin resistance to obesity and ways to combat; circadian misalignment– molecular level understanding of its contribution to obesity and ways to mitigate it; effective and individualized obesity treatment strategies for stress; molecular understanding of the influence of parental obesity on childhood overweight; molecular mechanisms of maternal smoking on childhood obesity; therapeutic interventions for obesity through recombinant hormones; role of gut hormones in the treatment of obesity; development of new digital tools for weight management interventions
(This special issue belongs to the Section Molecular Medicine)
Novel Immunotherapy for Neurological Diseases submission deadline 31 Mar 2025 | Viewed by 112 | Submission Open
Keywords: T cells; immune; neurological disorders; Alzheimer's disease
(This special issue belongs to the Section Molecular Medicine)
Tumorigenesis and Tumor Microenvironment
edited by
submission deadline 10 Apr 2025 | 4 articles | Viewed by 7181 | Submission Open
Keywords: tumorigenesis; tumor growth; tumor progression; tumor metastasis; cancers
(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)
Bioactive Molecules: Structure-Activity Relationship
edited by
submission deadline 10 Apr 2025 | 2 articles | Viewed by 5661 | Submission Open
Keywords: bioactive molecules; quantitative structure activity relationship (QSAR); QSAR based methodologies; QSAR multi-target; drug design and discovery; drug repurposing
(This special issue belongs to the Section Biochemistry, Molecular and Cellular Biology)
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