Skin Anti-Aging Strategies

A special issue of Cosmetics (ISSN 2079-9284).

Deadline for manuscript submissions: 20 January 2025 | Viewed by 4206

Special Issue Editor


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Guest Editor
Dsm-Firmenich, Perfumery & Beauty, Kaiseraugst, Switzerland
Interests: skin aging; photo-aging; pigmentation; skin hydration; skin inflammation; hair aging; cosmetics
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Special Issue Information

Dear Colleagues,

Anti-aging is always in high demand as a skin care claim in the cosmetics industry. Therefore, research on skin aging and the development of strategies and technologies for anti-aging are of paramount importance. More classical approaches comprise mechanisms such as anti-oxidant and DNA repair, anti-inflammation, or extracellular matrix protection and replenishment. More recent trends are the role of the skin microbiome in skin aging, senescence and senolytics, exosomes, or the inclusion of the senses, and neurocosmetics, to name a few. Skin aging can have various causes, such as UV irradiation, pollution, or more recent climate change in general, but also stress and lifestyle, among others. In addition, regional variations and the distinct needs of consumers and ethnicities become more and more apparent. This Special Issue of Cosmetics is the perfect home for your original paper, review, or communication on past and future trends and strategies in the field of skin anti-aging research and development. It can contain reports on molecular pathways, biochemical mechanisms, as well as human studies and applications such as innovative formulations and devices. We are looking forward to receiving your submissions. 

Dr. Remo Campiche
Guest Editor

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Keywords

  • skin aging
  • skin bioactives
  • pathways
  • technologies
  • applications
  • formulations
  • multi-ethnic skin
  • fragrances
  • artificial intelligence
  • sustainability

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Published Papers (2 papers)

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Research

22 pages, 11783 KiB  
Article
Willaertia Lysate: A Hydrobiome-Biosourced Ingredient with Multi-Site Antioxidative and Antiaging Properties
by Morgan Dos Santos, Julie Rorteau, Kilian Laho, Hanan Osman-Ponchet, Manon Barthe, Benjamin Quelard, Antoine Carlino, Adeline Saha and Sandrine Troussieux
Cosmetics 2024, 11(6), 200; https://doi.org/10.3390/cosmetics11060200 - 21 Nov 2024
Viewed by 287
Abstract
Aging is synonymous with the skin becoming increasingly thin and fragile, which is associated with a decrease in epidermal cell layers. Beyond this intrinsic aging process, the skin is continually exposed to environmental stressors such as UV radiation that accelerate aging. To fight [...] Read more.
Aging is synonymous with the skin becoming increasingly thin and fragile, which is associated with a decrease in epidermal cell layers. Beyond this intrinsic aging process, the skin is continually exposed to environmental stressors such as UV radiation that accelerate aging. To fight the signs of aging, a comprehensive program was implemented in this study to evaluate the efficacy of an innovative ingredient, Willaertia lysate, through a multi-scale approach encompassing cellular and advanced 3D skin models. The results show that Willaertia lysate, initially sourced from French Alps thermal spring waters, is able to (i) promote cell migration; (ii) improve the quality and abundance of the extracellular matrix in aged skins and in young skins exposed to UV radiation to a similar level to that in unexposed young skins; (iii) decrease tyrosinase activity and melanin content; and (iv) reduce oxidative stress after UV exposure by decreasing exposome markers such as protein carbonylation and lipid peroxidation expression. This complete set of coherent results demonstrates the global protective efficacy of Willaertia lysate against the effects of photoaging. This study is the first to report the use of a protozoan lysate as a natural and biosourced postbiotic active ingredient in the fields of cosmetics and dermocosmetics. Full article
(This article belongs to the Special Issue Skin Anti-Aging Strategies)
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19 pages, 2289 KiB  
Article
Anti-Aging Effects of Low-Molecular-Weight Collagen Peptide Supplementation on Facial Wrinkles and Skin Hydration: Outcomes from a Six-Week Randomized, Double-Blind, Placebo-Controlled Trial
by Juan Antonio Carrillo-Norte, Baldomero García-Mir, Lluis Quintana, Bruno Buracchio and Rafael Guerrero-Bonmatty
Cosmetics 2024, 11(4), 137; https://doi.org/10.3390/cosmetics11040137 - 12 Aug 2024
Viewed by 3411
Abstract
In recent decades, there has been a rising demand for anti-aging interventions aimed at postponing or potentially reversing indicators of skin aging. The use of collagen-based nutraceutical supplements has gained popularity as they have shown promise in enhancing skin health and reducing signs [...] Read more.
In recent decades, there has been a rising demand for anti-aging interventions aimed at postponing or potentially reversing indicators of skin aging. The use of collagen-based nutraceutical supplements has gained popularity as they have shown promise in enhancing skin health and reducing signs of aging. The aim of this randomized, placebo-controlled, blinded study was to investigate the effects of 2.5 g COLLinstant® LMW, a novel cosmeceutical containing low-molecular-weight (≤1000 Da) collagen peptides, on skin aging and health. The trial was conducted with 80 healthy women aged 30 years and older. They received a daily oral dose of either the food supplement (n = 40) or placebo (n = 40) for six weeks. Skin assessment was performed based on validated objective methods, such as Visioface 1000D (skin wrinkling), cutometry (elasticity and fatigue), and corneometry (skin hydration) at baseline (T0) and at week 6 (T6). After 6 weeks, participants that received collagen had significant improvements in biometric skin wrinkle parameters from baseline, with a reduction in volume by 46%, in area by 44%, and in depth by 9%, along with a greater increase in skin moisturization (by 34%) than those in the placebo group (p < 0.001). The food supplement did not significantly modify skin firmness or fatigue and had only slight beneficial effects on skin elasticity. The investigational product was well tolerated. The observed effects aligned closely with the subjective assessments reported by study participants. The study provides substantiated evidence supporting the efficacy of low-molecular-weight collagen peptides in restoring altered skin biometric parameters, as objectively assessed. Thus, regular supplementation with this nutraceutical may contribute to achieving smoother and more radiant skin. Full article
(This article belongs to the Special Issue Skin Anti-Aging Strategies)
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