Associations between Dermoscopy and Dermatopathology

A special issue of Dermatopathology (ISSN 2296-3529).

Deadline for manuscript submissions: 30 June 2025 | Viewed by 553

Special Issue Editors


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Guest Editor
Department of Dermatology, Faculty of Medicine, School of Health Sciences, University General Hospital of Larissa, University of Thessaly, 41334 Larissa, Greece
Interests: psoriasis; inflammatory dermatoses; vaccinations; dermoscopy; skin colour; skin cancer; oxidative stress
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Guest Editor Assistant
Department of Dermatology, Oncoderm Center One Day Clinic, 45332 Ioannina, Greece
Interests: dermoscopy; histopathology; skin cancer; basal cell carcinoma; artificial intelligence; squamous cell carcinoma; skin of colour; pediatric dermatology

Special Issue Information

Dear Colleagues,

It is well established that the most dermoscopic structures have corresponding histopathologic features and, therefore, dermoscopy can serve as an effective communication tool connecting clinicians and pathologists. In particular, when the clinical diagnosis is challenging, dermoscopy can guide the pathologists by providing visual clues, leading to a more accurate diagnosis.

The strong correlation between the features seen in dermoscopy and the histological characteristics can be observed in the relationship between the colors and patterns of the examining cutaneous lesions. The colors seen through dermoscopy correspond to the type of pigment, as well as the depth of the pigment. For example, the black color seen in dermoscopy can respond to the melanin in stratum corneum, while keratin structures represent the yellow color. With regard to dermoscopy patterns, thick curved lines observed during seborrhoeic keratosis dermoscopy observations are associated with marked epidermal acanthosis, while white clods seen in dermoscopy correspond to horn pseudocysts.

Therefore, in this Special Issue, we invite authors to submit studies, interesting cases and reviews that further bridge the gap between dermoscopy and histopathology correlations and outline the value of their relationship for dermatologic diagnosis and research.

Dr. Emmanouil Karampinis
Guest Editor

Dr. Olga Toli
Guest Editor Assistant

Manuscript Submission Information

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Dermatopathology is an international peer-reviewed open access quarterly journal published by MDPI.

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Keywords

  • dermoscopy
  • histopathology
  • pigmented lesions
  • skin cancer
  • inflammatory dermatoses
  • biopsy

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Published Papers (1 paper)

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Review

9 pages, 4793 KiB  
Review
“Chasing Rainbows” Beyond Kaposi Sarcoma’s Dermoscopy: A Mini-Review
by Emmanouil Karampinis, Olga Toli, Georgia Pappa, Anna Vardiampasi, Melpomeni Theofili, Efterpi Zafiriou, Mattheos Bobos, Aimilios Lallas, Elizabeth Lazaridou, Biswanath Behera and Zoe Apalla
Dermatopathology 2024, 11(4), 333-341; https://doi.org/10.3390/dermatopathology11040035 - 25 Nov 2024
Viewed by 379
Abstract
The dermoscopic rainbow pattern (RP), also known as polychromatic pattern, is characterized by a multicolored appearance, resulting from the dispersion of polarized light as it penetrates various tissue components. Its separation into different wavelengths occurs according to the physics principles of scattering, absorption, [...] Read more.
The dermoscopic rainbow pattern (RP), also known as polychromatic pattern, is characterized by a multicolored appearance, resulting from the dispersion of polarized light as it penetrates various tissue components. Its separation into different wavelengths occurs according to the physics principles of scattering, absorption, and interference of light, creating the optical effect of RP. Even though the RP is regarded as a highly specific dermoscopic indicator of Kaposi’s sarcoma, in the medical literature, it has also been documented as an atypical dermoscopic finding of other non-Kaposi skin entities. We aim to present two distinct cases—a pigmented basal cell carcinoma (pBCC) and an aneurysmatic dermatofibroma—that exhibited RP in dermoscopy and to conduct a thorough review of skin conditions that display RP, revealing any predisposing factors that could increase the likelihood of its occurrence in certain lesions. We identified 33 case reports and large-scale studies with diverse entities characterized by the presence of RP, including skin cancers (Merkel cell carcinoma, BCC, melanoma, etc.), adnexal tumors, special types of nevi (blue, deep penetrating), vascular lesions (acroangiodermatitis, strawberry angioma, angiokeratoma, aneurismatic dermatofibromas, etc.), granulation tissue, hypertrophic scars and fibrous lesions, skin infections (sporotrichosis and cutaneous leishmaniasis), and inflammatory dermatoses (lichen simplex and stasis dermatitis). According to our results, the majority of the lesions exhibiting the RP were located on the extremities. Identified precipitating factors included the nodular shape, lesion composition and vascularization, skin pigmentation, and lesions’ depth and thickness. These parameters lead to increased scattering and interference of light, producing a spectrum of colors that resemble a rainbow. Full article
(This article belongs to the Special Issue Associations between Dermoscopy and Dermatopathology)
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