Molecular Genetic Investigation of Rare Cancers
A special issue of Genes (ISSN 2073-4425). This special issue belongs to the section "Human Genomics and Genetic Diseases".
Deadline for manuscript submissions: closed (25 March 2024) | Viewed by 4033
Special Issue Editor
Interests: rare cancer; microRNA; microRNA genetics; microRNA expression; microRNA targeting; microRNA dysregulation; disease mechanisms; disease models; microRNA diagnostics; microRNA therapeutics
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Rare cancers are defined by their low incidence and prevalence in different populations. However, these cancers collectively account for more than 20 percent of all cancer diagnoses worldwide. Because of their infrequency, rare cancers are often challenging to diagnose, incompletely understood at the molecular level, and lack specific and effective treatments. The unrealistic need for large sample numbers also hampers many clinical studies. In this Special Issue, we focus on genetic, pathobiologic, and computational studies of molecular changes in rare cancer tissues, cell lines, and disease models. We are particularly interested in novel molecular diagnostic, mechanistic, and therapeutic studies. To overcome a major barrier in rare cancer research, well-performed omics-based small case series or n-of-1 studies are particularly encouraged. A fuller understanding of the molecular basis of rare cancers will advance our knowledge of rare cell biology and improve existing diagnostic and therapeutic approaches for these comparatively neglected cancers.
Dr. Neil Renwick
Guest Editor
Manuscript Submission Information
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Keywords
- rare cancers
- cancer biology
- molecular diagnostics
- disease mechanisms
- novel therapeutics
- N-of-1 studies
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