ijms-logo

Journal Browser

Journal Browser

Latest Treatment Strategy for Neurological Disorders

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Neurobiology".

Deadline for manuscript submissions: closed (30 September 2023) | Viewed by 11932

Special Issue Editor

Special Issue Information

Dear Colleagues,

To date, there are few effective treatments approved and available for patients with neurological disorders, and in many cases, the therapeutic options focus on the symptomatic management of disease manifestations, aiming to improve patients' quality of life.

In recent years, basic researchers and clinicians have worked together, sharing research projects and planning clinical trials, to improve this scenario, with results leading in some cases to a real therapeutic revolution, such as in spinal muscular atrophy (SMA). Important therapeutic advantages have also been achieved in other rare neurological pathologies both of genetic and autoimmune etiology, such as hereditary transthyretin amyloidosis (ATTRv) or myasthenia gravis. At the same time, innovative approaches have changed the therapeutic options for common neurological diseases, such as migraine.

Finally, an increasingly accurate metabolic–molecular characterization of hereditary and acquired neurological disorders (e.g., mitochondrial diseases, multiple sclerosis, neurodegenerative diseases of the central nervous system and movement disorders) is defining new therapeutic perspectives, sometimes unexpected.

For this Special Issue titled “Latest Treatment Strategy for Neurological Disorders”, we are looking for original research articles and state-of-the-art reviews on preclinical and clinical therapeutic approaches, both in common and rare neurological diseases, focused on a molecular point of view.

Dr. Guido Primiano
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • personalized medicine
  • neurological disorders
  • neurogenetic diseases
  • mitochondrial diseases
  • spinal muscular atrophy
  • neurodegenerative diseases
  • autoimmune disease
  • treatment
  • therapeutics
  • biological mechanisms

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.

Further information on MDPI's Special Issue polices can be found here.

Published Papers (1 paper)

Order results
Result details
Select all
Export citation of selected articles as:

Review

31 pages, 1762 KiB  
Review
Vitamin D in Neurological Diseases
by Domenico Plantone, Guido Primiano, Carlo Manco, Sara Locci, Serenella Servidei and Nicola De Stefano
Int. J. Mol. Sci. 2023, 24(1), 87; https://doi.org/10.3390/ijms24010087 - 21 Dec 2022
Cited by 24 | Viewed by 11271
Abstract
Vitamin D may have multiple effects on the nervous system and its deficiency can represent a possible risk factor for the development of many neurological diseases. Recent studies are also trying to clarify the different effects of vitamin D supplementation over the course [...] Read more.
Vitamin D may have multiple effects on the nervous system and its deficiency can represent a possible risk factor for the development of many neurological diseases. Recent studies are also trying to clarify the different effects of vitamin D supplementation over the course of progressive neurological diseases. In this narrative review, we summarise vitamin D chemistry, metabolism, mechanisms of action, and the recommended daily intake. The role of vitamin D on gene transcription and the immune response is also reviewed. Finally, we discuss the scientific evidence that links low 25-hydroxyvitamin D concentrations to the onset and progression of severe neurological diseases, such as multiple sclerosis, Parkinson’s disease, Alzheimer’s disease, migraine, diabetic neuropathy and amyotrophic lateral sclerosis. Completed and ongoing clinical trials on vitamin D supplementation in neurological diseases are listed. Full article
(This article belongs to the Special Issue Latest Treatment Strategy for Neurological Disorders)
Show Figures

Figure 1

Back to TopTop