Pathophysiology and Novel Therapeutic Strategies of Neurological Diseases
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: closed (20 May 2024) | Viewed by 2042
Special Issue Editor
Interests: neurogenetics; neurological diseases; neurodegeneration; clinical neurophysiology; neuromuscular disorders
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Neurological disorders are a leading cause of disability and the second leading cause of death worldwide. In the coming years, we expect an increase in the number of deaths and people with disabilities due to neurological diseases, as a result of population growth and ageing. Despite dramatic improvements in the diagnosis of common and rare disorders, especially for the spread of omics technologies, significant results have not been obtained with regard to the associated pathogenetic mechanisms and the identification of effective treatments. Translational research in neuroscience can bridge this gap by transferring knowledge gained through basic science into therapeutic interventions. Indeed, a 'bench-to-bedside' approach, based on the application in clinical practice of the results obtained from the investigation of pathogenetic mechanisms using different disease models, has profoundly changed the therapeutic scenario of neurological diseases in recent years. Some examples in this regard are represented by spinal muscular atrophy, hereditary transthyretin amyloidosis, or myasthenia gravis. At the same time, an accurate pathophysiological characterization of hereditary and acquired neurological disorders can define new therapeutic perspectives.
For this Special Issue titled “Pathophysiology and Novel Therapeutic Strategies of Neurological Diseases”, we are looking for original research articles and state-of-the-art reviews on the pathophysiological mechanisms underlying common and rare neurological diseases and on innovative therapeutic approaches to these disorders.
Dr. Guido Primiano
Guest Editor
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Keywords
- neurological disorders
- neurogenetic diseases
- pathophysiological mechanisms
- mitochondrial diseases
- spinal muscular atrophy
- neurodegenerative diseases
- treatment
- therapeutics
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