Genetic Insights into Host-Viral Response and Pathogenesis: 2nd Edition
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Genetics and Genomics".
Deadline for manuscript submissions: 20 February 2025 | Viewed by 1904
Special Issue Editor
Interests: herpes simplex; in vitro molecular studies; virus-host interaction pathways
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Numerous evidence shows that genetics play a leading role in influencing the course of many infectious diseases, and determine the probability of developing a disease. The clearance of the microbial agent, which is capable of influencing organ susceptibility and/or the effectiveness of the immune response, is strictly dependent on genetic factors. For this reason, it is important to understand how, at the molecular level, viruses can dynamically influence chromatin remodeling to allow for the regulation of gene expression and other processes that require access to cellular DNA, and how these host–pathogen interactions can influence the genetic diversity of both organisms. Infections are perhaps one of the main selective pressures acting on humans. Knowledge of the virus–host molecular interactions and the identification of the key factors that modify the cellular genome, gene expression and epigenetic modifications are essential for understanding the fate of infections, viral diseases and their pathogenesis. However, not much is known about these interactions; as such, further exploration is required as it could provide new perspectives for prevention of infections, drug-treatments and vaccine development.
This Special Issue, ‘Genetic Insights into Host-Viral Response and Pathogenesis 2.0’ aims to collate original articles, reviews, as well as short communications, that focus on host–virus interaction, and the molecular and genetic mechanisms of host–virus response and pathogenesis.
Prof. Dr. Peggy Marconi
Guest Editor
Manuscript Submission Information
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Keywords
- viruses
- host–virus interaction
- genetics
- molecular aspects
- epigenetics
- immunity
- prevention
- drug-treatments
- vaccine development
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