Molecular Biomarkers in Cancers: Advances and Challenges, 2nd Edition
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: 30 November 2024 | Viewed by 1113
Special Issue Editors
Interests: cardiovascular disease; diabetes; nutrition; early-stage lung cancer
Special Issues, Collections and Topics in MDPI journals
Interests: oncology; research; pharmacology; ethics; cancer; cardiology; diabetes; innovation; regulatory
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
There are several diagnostic techniques and procedures currently used for the diagnosis of cancer. Although computed tomography, magnetic resonance imaging, and ultrasound technology are considered gold-standard procedures for the detection of cancer, they are often associated with an undesirably high level of false positives, are also expensive, present accessibility issues, and involve exposure to ionizing radiation. Most of the non-imaging techniques for cancer detection are employed to corroborate biomarkers that are overexpressed in cancer cells. A number of assays have been developed to measure protein, microRNA, circulating DNA, and methylated DNA biomarkers in the blood for the detection of cancer. In addition, biopsies for molecular and biomarker diagnosis have also been utilized, but they are invasive and uncomfortable for patients. While these approaches have clinical value that is more specific to late-stage cancer, they have limited value for the early detection of cancer. Accordingly, the identification of highly specific and highly selective novel molecular biomarkers for cancer diagnosis that also provide information on staging of the disease is warranted. In this Special Issue, we describe the pros and cons of current molecular approaches used in the diagnosis of cancer, as well as the technical advances in and challenges for establishing molecular biomarkers for determining the risk, detection, and progression of cancer.
Dr. Paramjit S. Tappia
Dr. Bram Ramjiawan
Guest Editors
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Keywords
- cancer
- cancer staging
- diagnostic tools
- novel biomarkers
- proteomics
- molecular markers
- metabolic profiling
- prognostic value
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