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Research of Hydroxyapatite-Based Materials and Their Applications

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Materials Science".

Deadline for manuscript submissions: 20 February 2025 | Viewed by 1106

Special Issue Editor


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Guest Editor
National Institute of Materials Physics, Atomistilor Street, No. 405A, P.O. Box MG 07, 077125 Magurele, Romania
Interests: biomaterials; biomedical applications; biotechnology; environmental applications; food industry; hydroxyapatite; magnetic properties; iron oxide nanoparticles; structural properties; surface properties; antimicrobial properties; antimicrobial coatings; pharmaceutical applications; colloidal properties
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Special Issue Information

Dear Colleagues,

Due to their unique features and qualities, hydroxyapatite (HAp)-based nanomaterials and nanocomposites are used in advanced applications in domains such as environmental remediation or biomedicine (e.g., drug and protein delivery systems). The efficiency of hydroxyapatite-based materials is strongly related to their physico-chemical (e.g., size, crystallinity, morphology, porosity, pollutant adsorption capacity, etc.) and biological properties (e.g., antimicrobial activity, biocompatibility, drug delivery ability, etc.).

This Special Issue will explore the recent advances in their fabrication, functionalization and applications. Despite the large number of studies reported in the literature, further studies are needed to better clarify important aspect such as: the interaction mechanism between hydroxyapatite-based materials and the environment, the advantages/disadvantages of their uses, etc.

This Special Issue welcomes original papers and reviews addressing the different hydroxyapatite-based materials (coatings, powders, suspension, scaffolds, etc.) and their applications in various domains such as biomedical, environmental remediation, food industry, drug delivery, cosmetic, orthopedy/dentistry, etc.

Dr. Daniela Predoi
Guest Editor

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Keywords

  • hydroxyapatite
  • nanobiocomposite
  • biomedical applications
  • coatings
  • environment remediation
  • biological properties
  • drug delivery
  • pollutant adsorption efficiency
  • morphology and structural features

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Published Papers (1 paper)

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Research

20 pages, 1590 KiB  
Article
The Ways of Forming and the Erosion/Decay/Aging of Bioapatites in the Context of the Reversibility of Apatites
by Agnieszka Lasota, Mieczysław Gorzelak, Karolina Turżańska, Wojciech Kłapeć, Maciej Jarzębski, Tomasz Blicharski, Jarosław Pawlicz, Marek Wieruszewski, Mirosław Jabłoński and Andrzej Kuczumow
Int. J. Mol. Sci. 2024, 25(20), 11297; https://doi.org/10.3390/ijms252011297 - 21 Oct 2024
Viewed by 763
Abstract
This study primarily focused on the acid erosion of enamel and dentin. A detailed examination of the X-ray diffraction data proves that the products of the acid-caused decay of enamel belong to the family of isomorphic bioapatites, especially calcium-deficient hydroxyapatites. They are on [...] Read more.
This study primarily focused on the acid erosion of enamel and dentin. A detailed examination of the X-ray diffraction data proves that the products of the acid-caused decay of enamel belong to the family of isomorphic bioapatites, especially calcium-deficient hydroxyapatites. They are on a trajectory towards less and less crystallized substances. The increase in Bragg’s parameter d and the decrease in the energy necessary for the changes were coupled with variability in the pH. This was valid for the corrosive action of acid solutions with a pH greater than 3.5. When the processes of natural tooth aging were studied by X-ray diffraction, a clear similarity to the processes of the erosion of teeth was revealed. Scarce data on osteoporotic bones seemed to confirm the conclusions derived for teeth. The data concerning the bioapatite decays were confronted with the cycles of apatite synthesis/decay. The chemical studies, mainly concerning the Ca/P ratio in relation to the pH range of durability of popular compounds engaged in the synthesis/decay of apatites, suggested that the process of the formation of erosion under the influence of acids was much inverted in relation to the process of the formation of apatites, starting from brushite up to apatite, in an alkaline environment. Our simulations showed the shift between the family of bioapatites versus the family of apatites concerning the pH of the reaction environment. The detailed model stoichiometric equations associated with the particular stages of relevant processes were derived. The synthesis processes were alkalization reactions coupled with dehydration. The erosion processes were acid hydrolysis reactions. Formally, the alkalization of the environment during apatite synthesis is presented by introducing Ca(OH)2 to stoichiometric equations. Full article
(This article belongs to the Special Issue Research of Hydroxyapatite-Based Materials and Their Applications)
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