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Hydroxyapatite Composite: Development, Fabrication and Characterization

A special issue of Materials (ISSN 1996-1944). This special issue belongs to the section "Advanced Composites".

Deadline for manuscript submissions: closed (20 June 2023) | Viewed by 7039

Special Issue Editors


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National Institute of Materials Physics, Atomistilor Street, No. 405A, P.O. Box MG 07, 077125 Magurele, Romania
Interests: biomaterials; biomedical applications; biotechnology; environmental applications; food industry; hydroxyapatite; magnetic properties; iron oxide nanoparticles; structural properties; surface properties; antimicrobial properties; antimicrobial coatings; pharmaceutical applications; colloidal properties
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1. Department of General Surgery, Carol Davila University of Medicine and Pharmacy, 8 Eroii Sanitari, Sector 5, 050474 Bucharest, Romania
2. Emergency Hospital Floreasca Bucharest, 8 Calea Floreasca, 014461 Bucharest, Romania
Interests: abdominal surgery; laparoscopic surgery; minimally invasive surgery; gastrointestinal surgery; colorectal surgery; hernia surgery; advance laparoscopic surgery; surgical oncology; cancer surgery; hepatobiliary surgery
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Special Issue Information

Dear Colleagues,

The biomaterials based on hydroxyapatite composite are currently in the attention of researchers due to their unique properties that make them suitable for various applications in the biomedical field. Areas such as tissue engineering, cancer, infection, drug delivery systems, and depollution are areas that could benefit fully from the progress of research on hydroxyapatite composite. The patient’s quality of life could be enhanced by using new hydroxyapatite composites as bone fillers, loading agent, antimicrobial agent, coating of implants, etc.

This Special Issue will focus on novel advances and applications of hydroxyapatite composites. The main objective is to highlight the recent progress in development, fabrication and characterization of hydroxyapatite composites with potential application in biomedical and environmental fields (infection treatment and prevention, implants, tissue engineering, drug delivery, coatings, cancer research, water and soil depollution and other relevant applications). Special attention will be paid in this Special Issue to the physico-chemical (including surface and colloidal properties) and biological properties (including antimicrobial ones) of new hydroxyapatite composites and their potential applications in the biomedical and environmental fields.

Research and long review papers containing new findings and perspectives on the field of hydroxyapatite composite (development, fabrication and characterization) and their recently applications are welcomed for this Special Issue.

Dr. Daniela Predoi
Prof. Dr. Mircea Beuran
Dr. Simona Liliana Iconaru
Dr. Carmen Steluta Ciobanu
Guest Editors

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Keywords

  • hydroxyapatite composite
  • biomaterials
  • drug delivery
  • antimicrobial properties
  • hydroxyapatite scaffolds
  • environmental field
  • coatings

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Published Papers (2 papers)

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Research

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17 pages, 5656 KiB  
Article
The Influence of Nanosilica on Properties of Cement Based on Tetracalcium Phosphate/Monetite Mixture with Addition of Magnesium Pyrophoshate
by Radoslava Stulajterova, Maria Giretova, Lubomir Medvecky, Tibor Sopcak, Lenka Luptakova and Vladimir Girman
Materials 2022, 15(22), 8212; https://doi.org/10.3390/ma15228212 - 18 Nov 2022
Cited by 1 | Viewed by 1542
Abstract
The effect of nanosilica on the microstructure setting process of tetracalcium phosphate/nanomonetite calcium phosphate cement mixture (CPC) with the addition of 5 wt% of magnesium pyrophosphate (assigned as CT5MP) and osteogenic differentiation of mesenchymal stem cells cultured in cement extracts were studied. A [...] Read more.
The effect of nanosilica on the microstructure setting process of tetracalcium phosphate/nanomonetite calcium phosphate cement mixture (CPC) with the addition of 5 wt% of magnesium pyrophosphate (assigned as CT5MP) and osteogenic differentiation of mesenchymal stem cells cultured in cement extracts were studied. A more compact microstructure was observed in CT5MP cement with 0.5 wt% addition of nanosilica (CT5MP1Si) due to the synergistic effect of Mg2P2O7 particles, which strengthened the cement matrix and nanosilica, which supported gradual growth and recrystallization of HAP particles to form compact agglomerates. The addition of 0.5 wt% of nanosilica to CT5MP cement caused an increase in CS from 18 to 24 MPa while the setting time increased almost twofold. It was verified that adding nanosilica to CPC cement, even in a low amount (0.5 and 1 wt% of nanosilica), positively affected the injectability of cement pastes and differentiation of cells with upregulation of osteogenic markers in cells cultured in cement extracts. Results revealed appropriate properties of these types of cement for filling bone defects. Full article
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Review

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30 pages, 1904 KiB  
Review
Recent Progress in the Application of Hydroxyapatite for the Adsorption of Heavy Metals from Water Matrices
by Roxana Ioana Brazdis, Irina Fierascu, Sorin Marius Avramescu and Radu Claudiu Fierascu
Materials 2021, 14(22), 6898; https://doi.org/10.3390/ma14226898 - 15 Nov 2021
Cited by 25 | Viewed by 4344
Abstract
Wastewater treatment remains a critical issue globally, despite various technological advancements and breakthroughs. The study of different materials and technologies gained new valences in the last years, in order to obtain cheap and efficient processes, to obtain a cleaner environment for future generations. [...] Read more.
Wastewater treatment remains a critical issue globally, despite various technological advancements and breakthroughs. The study of different materials and technologies gained new valences in the last years, in order to obtain cheap and efficient processes, to obtain a cleaner environment for future generations. In this context, the present review paper presents the new achievements in the materials domain with highlights on apatitic materials used for decontamination of water loaded with heavy metals. The main goal of this review is to present the adsorptive removal of heavy metals using hydroxyapatite-based adsorbents, offering a general overview regarding the recent progress in this particular area. Developing the current review, an attempt has been made to give appropriate recognition to the most recent data regarding the synthesis methods and targeted pollutants, including important information regarding the synthesis methods and precursors, morphological characteristics of the adsorbent materials and effectiveness of processes. Full article
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