Diabetic Retinopathy: Mechanisms Underlying Pathophysiology and Therapies 2.0
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: closed (31 December 2020) | Viewed by 8072
Special Issue Editor
Interests: drug target discovery and drug development for disorders of the CNS and retina; calcium signaling; neuroprotection; neurodegeneration; synaptic signaling; neurophysiology
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The identification of mechanisms underlying the pathophysiology and therapies of diabetic retinopathy continues to be an area of significant research efforts, attracting scientists from a diverse range of fields, including neuroscience, pharmacology, and medicinal chemistry, among several others. With the ultimate goal to generate intervention strategies that slow or even reverse structural and functional degeneration of the retina and that attenuate or eliminate vascular complications input from numerous fields, such as neurology, ophthalmology, and endocrinology, appears critically needed, as effective therapies for diabetic retinopathy are lacking.
Research efforts towards treating or curing diabetic retinopathy are characteristic for how clinical practice and basic and translational research inform each other and how such interactions can result in novel therapeutic strategies of high clinical relevance. Recent methodological advances in synthetic and medicinal chemistry, mass spectrometry, proteomics, drug target discovery, and drug development have generated significant developments in this field. Therefore, this Special Issue invites manuscript submissions, namely, research and review papers, targeting the gamut of methodological and scientific innovation in this field. Of specific interest to this Special Issue are papers focused on the discovery and mechanistic characterization of novel drug targets, signaling pathways, and mechanisms of action as they are relevant for diabetic retinopathy. These contributions can be general and broad in their basic science and translational-research-focused or highly focused on specific research models related to structural and functional degeneration of the retina and vascular complications.
Dr. Peter Koulen
Guest Editor
Manuscript Submission Information
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Keywords
- Neuroprotection
- retina
- diabetic macular edema
- proliferative and non-proliferative diabetic retinopathy therapy development
- pathophysiology
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