Ion Channels in Eye Development, Health, and Disease
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biology".
Deadline for manuscript submissions: 20 August 2025 | Viewed by 2488
Special Issue Editors
Interests: synaptic transmission; calcium and vesicle dynamics; retina; ribbon synapse; neurodegeneration
Interests: inherited retinal dystrophies; age-related macular degeneration; glaucoma; gene therapy; inflammation
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Ion channels are membrane-spanning multimeric proteins expressed by all living organisms and serve the purpose of transporting both organic and inorganic ions. The regulation of ions at a steady state level is a key phenomenon for proper cellular function. Recent advancements in imaging, physiology, crystallography, computational technology, molecular modeling, molecular biology tools, and systems genetics have facilitated an understanding of ion channels including the structure–function relationship of ion channels and the development of precision medicine.
The eye is an excellent model for understanding how the structure and function of ion channels correlate during development, health, and disease. This Special Issue aims to provide a comprehensive overview of the roles ion channels play from the perspective of the eye during development, health, disease, and potential therapeutic targets. This Special Issue welcomes original research papers, reviews, mini-reviews, perspectives, and opinion articles that will provide insights into the novel and existing approaches to:
- Explore specific roles of ion channels in development, health, and disease.
- Novel approaches to study the structure and function of ion channels.
- Current understanding of channelopathies and drug development.
- Studies in all animal species and models of retinal diseases are welcome, as are comparative studies across animal models.
Dr. Thirumalini Vaithianathan
Dr. T. J. Hollingsworth
Guest Editors
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Keywords
- eye development
- eye health and disease
- ion channels
- channelopathies
- physiology
- computational technology
- molecular modeling
- molecular biology tools
- pharmacology
- systems genetics
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