Extracellular Vesicles in the Pathogenesis of Disease and Their Potential Role as Therapeutic Targets
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Biochemistry".
Deadline for manuscript submissions: 20 April 2025 | Viewed by 1930
Special Issue Editor
Interests: extracellular vesicles; microparticles; mechanisms underlying microparticle generation; intercellular communication; inflammatory markers; miRNAs; lung inflammation; lung diseases
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Extracellular vesicles (EVs) are small, membrane-bound structures released by various cell types into the extracellular environment. Exosomes, microparticles and apoptotic bodies, which differ in composition, biogenesis and size, belong to this family.
EVs have emerged as key players in the pathogenesis of various diseases, influencing disease progression and contributing to intercellular communication within the microenvironment. These small membrane-bound structures carry a cargo of proteins, lipids and nucleic acids, including microRNAs, which can regulate gene expression in recipient cells. Recently, several studies have evaluated the exciting prospect of using EVs as therapeutic targets. Modulating the biogenesis, release and content of EVs may offer promising therapeutic avenues.
With this Special Issue, we invite researchers to contribute with either original research (both in vivo or in vitro studies) or review articles focusing on EVs in the pathogenesis of disease and their potential role as therapeutic targets.
Dr. Tommaso Neri
Guest Editor
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Keywords
- extracellular vesicles
- exosome
- microparticles
- EVs as therapeutic targets
- EVs in the pathogenesis of disease
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