Translating Gold Nanoparticles to Diagnostics and Therapeutics 3.0
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: closed (22 November 2020) | Viewed by 3087
Special Issue Editor
Interests: anomedicine; application of DNA/RNA systems for nanobiotechnology; biosensing; molecular diagnostics and therapeutics; advanced drug delivery systems; gene silencing
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Due to their distinctive physical-chemical properties, gold nanoparticles are amongst the most widely-used nanoscale platforms for (molecular) diagnostics and therapeutics. The chemical stability and apparent lack of toxicity of gold nanoparticles and their biomolecular conjugates have been proposed for wide application in therapeutics, imaging modalities, and vectorization strategies for molecular modulators such as gene silencing, drug delivery, specific targeting of cellular pathways, etc. Because of their common molecular ground, these approaches have been synergistically coupled together into molecular theranostics systems that allow for radical new in vivo diagnostics modalities while simultaneously tackling molecular disequilibria that leads to disease. We have now reached a point where tremendous potential must be evaluated, that is, how gold nanoparticle-based systems have been making their way to the clinics. From the plethora of conceptual proposals, only a few make it through effective evaluation in the clinical setting. Current trends and the optimization of gold nanoparticle-based platforms for diagnostics and therapeutics towards effective translation to the clinical setting will be the focus of this Special Issue.
Prof. Pedro Viana Baptista
Guest Editor
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Keywords
- Gold nanoparticles
- biosensor
- DNA/RNA
- point of care
- molecular diagnostics
- drug delivery
- imaging
- clinical applications
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