Natural and Semi-Synthetic Small Molecules in Drug Discovery 2.0
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Bioactives and Nutraceuticals".
Deadline for manuscript submissions: closed (15 July 2022) | Viewed by 3141
Special Issue Editor
Interests: natural products chemistry; bioactive small molecules; anti-inflammatory drugs; pro-apoptotic drugs; endoplasmic reticulum stress; proteasome inhibitors
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Small molecules continue to be the most relevant set of therapeutic options for most human pathologies.
The process of drug discovery is complex and can arise from several strategies; however, naturally occurring molecules are still one of the most prolific sources of new chemical entities with applications in human health. However, these molecules can frequently be upgraded or enhanced in their potency and selectivity by conducting structural changes. For this reason, derivatives obtained by hemi-synthesis are also pivotal players in the process of drug discovery and development.
This Special Issue will focus on the process of drug discovery from naturally occurring bioactive small molecules and their hemi-synthetic derivatives. Several diseases will be addressed, including but not limited to cancer, as well as inflammatory, neurodegenerative, and metabolic diseases.
Prof. Dr. David M. Pereira
Guest Editor
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Keywords
- bioactive small molecules
- natural molecules
- natural products chemistry
- hemi-synthesis
- medicinal chemistry
- cancer
- inflammation
- neurodegenerative diseases
- metabolic diseases
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