Functional Biomaterials and Digital Technologies in Dentistry: From Bench to Bedside—2nd Edition

A special issue of Journal of Functional Biomaterials (ISSN 2079-4983). This special issue belongs to the section "Dental Biomaterials".

Deadline for manuscript submissions: 31 December 2024 | Viewed by 6893

Special Issue Editors

Department of Prosthodontics, School and Hospital of Stomatology, Guangzhou Medical University, Guangzhou, China
Interests: implant dentistry; digital dentistry; dental materials; biodegradable metals; additive manufacturing; biomaterials
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Guest Editor
Department of Prosthodontics, Geriatric Dentistry and Craniomandibular Disorders, Charité-Universitätsmedizin Berlin, 14197 Berlin, Germany
Interests: dentistry; maxillofacial prosthetics; 3D printing; additive manufacturing; CAD; digitization of education
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The development of dentistry requires an interdisciplinary approach that integrates the advancements of medicine, materials science and engineering, and computer science. To date, various functional biomaterials have been developed and proposed for oral and maxillofacial applications, due to their excellent biocompatibility, superior mechanical properties, and proper biofunctionality. In addition, advancements in digital technologies for biomaterials have attracted increasing attention. However, the translation process of functional biomaterials and digital technologies from bench to clinic remains extremely challenging.

This Special Issue, entitled “Functional Biomaterials and Digital Technologies in Dentistry: from Bench to Bedside”, aims to provide insight into the recent advances in functional biomaterials and digital technologies. It intends to explore opportunities for basic research, dental education, and the clinical application of biomaterials and digital technologies. The main topics of this Special Issue include, but are not limited to, the following: advanced functional biomaterials (metals, ceramics, polymers, and composites) and digital technologies (CAD/CAM milling, 3D printing, bioprinting, 4D printing, and artificial intelligence) in dental applications.

We invite you to submit a manuscript and present your recent research articles, reviews and communications that reveal the current state of the art and future trends in this field.

Dr. Ping Li
Dr. Alexey Unkovskiy
Guest Editors

Manuscript Submission Information

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Keywords

  • dental materials
  • digital dentistry
  • metals
  • ceramics
  • polymers
  • CAD/CAM
  • 3D printing

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Published Papers (3 papers)

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Research

26 pages, 7508 KiB  
Article
Complete Digital Workflow for Manufacturing Presurgical Orthodontic Palatal Plates in Newborns and Infants with Cleft Lip and/or Palate
by Christina Weismann, Alexander B. Xepapadeas, Marit Bockstedte, Bernd Koos, Michael Krimmel, Christian F. Poets and Maite Aretxabaleta
J. Funct. Biomater. 2024, 15(10), 301; https://doi.org/10.3390/jfb15100301 - 8 Oct 2024
Viewed by 664
Abstract
Deciding on the implementation or modification of steps in daily clinical care is a nuanced process that demands careful evaluation. This is crucial not only for selecting the most appropriate solution but also for achieving the best treatment outcome. Thus, implementing a workflow [...] Read more.
Deciding on the implementation or modification of steps in daily clinical care is a nuanced process that demands careful evaluation. This is crucial not only for selecting the most appropriate solution but also for achieving the best treatment outcome. Thus, implementing a workflow for treating cleft lip and/or palate patients with a presurgical orthodontic cleft-covering plate needs to consider objective factors, prioritized from most to least important: safety and quality level, user-friendliness, feasibility, and, finally, efficiency and cost. The goal of this workflow is to integrate CAD/CAM technologies into daily clinical routine to enhance technical and clinical efficiency, reduce the burden of cleft care, and simplify the implementation of these technologies in other facilities. To achieve this, a methodology based on intraoral scanning and additive manufacturing is employed to produce patient-specific passive palatal plates. The approach describes possible pitfalls and their resolution within the routine of a cleft centre, along with an exemplary case scenario. Comparative analysis between the digital workflow and the conventional process demonstrated the digital approach to be safer, higher in quality, more user-friendly, feasible, and cost- and time-effective than the conventional process. Full article
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12 pages, 5907 KiB  
Article
Cytocompatibility of Polymers for Skin-Contact Applications Produced via Pellet Extrusion
by Sakine Deniz Varsavas, Paweł Michalec, Mohammed Khalifa, Ping Li and Sebastian Spintzyk
J. Funct. Biomater. 2024, 15(7), 179; https://doi.org/10.3390/jfb15070179 - 29 Jun 2024
Viewed by 4455
Abstract
Orthoses and prostheses (O&P) play crucial roles in assisting individuals with limb deformities or amputations. Proper material selection for these devices is imperative to ensure mechanical robustness and biocompatibility. While traditional manufacturing methods have limitations in terms of customization and reproducibility, additive manufacturing, [...] Read more.
Orthoses and prostheses (O&P) play crucial roles in assisting individuals with limb deformities or amputations. Proper material selection for these devices is imperative to ensure mechanical robustness and biocompatibility. While traditional manufacturing methods have limitations in terms of customization and reproducibility, additive manufacturing, particularly pellet extrusion (PEX), offers promising advancements. In applications involving direct contact with the skin, it is essential for materials to meet safety standards to prevent skin irritation. Hence, this study investigates the biocompatibility of different thermoplastic polymers intended for skin-contact applications manufactured through PEX. Surface morphology analysis revealed distinct characteristics among materials, with TPE-70ShA exhibiting notable irregularities. Cytotoxicity assessments using L929 fibroblasts indicated non-toxic responses for most materials, except for TPE-70ShA, highlighting the importance of material composition in biocompatibility. Our findings underscore the significance of adhering to safety standards in material selection and manufacturing processes for medical devices. While this study provides valuable insights, further research is warranted to investigate the specific effects of individual ingredients and explore additional parameters influencing material biocompatibility. Overall, healthcare practitioners must prioritize patient safety by meticulously selecting materials and adhering to regulatory standards in O&P manufacturing. Full article
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13 pages, 3439 KiB  
Article
Effect of the Inter-Tooth Distance and Proximal Axial Wall Height of Prepared Teeth on the Scanning Accuracy of Intraoral Scanners
by So-Yeun Kim, Keunbada Son, Soo Kyum Bihn and Kyu-Bok Lee
J. Funct. Biomater. 2024, 15(5), 115; https://doi.org/10.3390/jfb15050115 - 25 Apr 2024
Viewed by 1301
Abstract
This study aimed to analyze the effect of the height of the proximal axial wall of the prepared tooth and the distance between the adjacent tooth and the prepared tooth on the scan accuracy of intraoral scanners. Ten working casts with maxillary first [...] Read more.
This study aimed to analyze the effect of the height of the proximal axial wall of the prepared tooth and the distance between the adjacent tooth and the prepared tooth on the scan accuracy of intraoral scanners. Ten working casts with maxillary first molars prepared to receive zirconia crowns were randomly obtained from a dental clinic. Each of the 10 casts was scanned using two intraoral scanners (i700; MEDIT and CS3600; Carestream; computer-aided design [CAD] test model, CTM; N = 15 per working cast) 15 times per scanner. Individual dies of the prepared teeth were fabricated, and high-precision scan data were acquired using a laboratory scanner (CAD reference model, CRM; N = 1). CTMs were aligned relative to the prepared tooth of CRMs by using three-dimensional inspection software (Ver 2018.1.0; Control X; 3D Systems). Data were statistically analyzed using an independent t-test and one-way analysis of variance for between-group comparisons (α = 0.05). The inaccuracy in the proximal regions (mesial or distal) of the prepared tooth was higher than that in the buccal and lingual regions (p < 0.05). The scan accuracy was not correlated with the variables when the distance between the adjacent tooth and the prepared tooth was ≥2.0 mm and the height of the proximal axial wall of the prepared tooth was <3.0 mm (p > 0.05). Therefore, an excellent scan accuracy can be obtained using an intraoral scanner when the distance between the adjacent tooth and the prepared tooth is ≥2.0 mm and the proximal axial wall height of the prepared tooth is <3.0 mm. Full article
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