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New Biomaterials in Periodontology and Implantology
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New Biomaterials in Periodontology and Implantology

A special issue of Journal of Functional Biomaterials (ISSN 2079-4983). This special issue belongs to the section "Dental Biomaterials".

Deadline for manuscript submissions: 31 May 2025 | Viewed by 4039

Special Issue Editors

Dr. Yaniv Mayer

E-Mail Website
Guest Editor
1. Department of Periodontology, School of Graduate Dentistry, Rambam Health Care Campus, Haifa, Israel
2. The Ruth and Bruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa 3525422, Israel
Interests: periodontology; peri-implantitis; digital dentistry; biomaterials; dental implants; perio-systemic
Prof. Dr. Jamil Awad Shibli

E-Mail Website
Guest Editor
Department of Periodontology, Dental Research Division, Guarulhos University, Guarulhos 07023-070, Brazil
Interests: periodontology and oral implantology; mainly peri-implant diseases; guided bone regeneration; laser; PDT; growth factors; implant surface topographies; digital workflow; RCT
Special Issues, Collections and Topics in MDPI journals
Dr. Ofir Ginesin

E-Mail Website
Guest Editor
1. Department of Periodontology, School of Graduate Dentistry, Rambam Health Care Campus, Haifa, Israel
2. The Ruth and Bruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa 3525422, Israel
Interests: peri-implantitis; immunology; dental implants; periodontitis; digital dentistry

Special Issue Information

Dear Colleagues,

This Special Issue on new biomaterials in periodontology and implantology aims to highlight the cutting-edge advancements and interdisciplinary approaches that are shaping the future of dental treatments. It is dedicated to exploring the role of biomaterials in enhancing the efficacy, durability, and biocompatibility of periodontal and implant therapies. It seeks to bridge the gap in translational research by showcasing novel materials, technologies, and methodologies that promise to revolutionize patient care in periodontology and implantology.

The scope of this Special Issue encompasses, but is not limited to, the development and characterization of new biomaterials, advances in tissue engineering for periodontal and peri-implant regeneration, innovations in implant surface modifications, and the application of nanotechnology in dental implants, including in the treatment of peri-implant diseases. By compiling research articles, reviews, and case reports, this Special Issue aims to provide a comprehensive overview of the current trends, challenges, and future directions in the field.

Situated within the existing literature, this Special Issue will serve as a critical resource for researchers, clinicians, and academics, encouraging the exchange of ideas and fostering collaborations across disciplines. It aims to fill gaps in our knowledge, challenge existing paradigms, and inspire further research and development in the quest for more effective and patient-friendly periodontal and implantology solutions.

Dr. Yaniv Mayer
Prof. Dr. Jamil Awad Shibli
Dr. Ofir Ginesin
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Functional Biomaterials is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • biomaterials
  • periodontology
  • implantology
  • tissue engineering
  • nanotechnology
  • surface modifications
  • biocompatibility
  • growth factors
  • lasers

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Further information on MDPI's Special Issue polices can be found here.

Published Papers (3 papers)

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Research

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12 pages, 5389 KiB  
Article
Effects of Platelet-Rich Fibrin on Bone Healing Around Implants Placed in Maxillary Sinuses: A Histomorphometric Assessment in Rabbits
by Gustavo Augusto Grossi-Oliveira, Eduardo Dallazen, Thabet Asbi, João Matheus Fonseca-Santos, Paulo Domingos Ribeiro-Júnior, Jamil A. Shibli, Cinthya Massari Grecco, Osvaldo Magro-Filho, Carlos Fernando Mourão, Doron Haim, Yaniv Mayer and Leonardo P. Faverani
J. Funct. Biomater. 2024, 15(12), 375; https://doi.org/10.3390/jfb15120375 - 12 Dec 2024
Viewed by 780
Abstract
This study investigated the effect of platelet-rich fibrin (PRF) on bone healing around implants placed in elevated sinus cavities. Forty New Zealand albino rabbits were divided into eight groups, based on the time of sacrifice (14 or 40 days) and the material used: [...] Read more.
This study investigated the effect of platelet-rich fibrin (PRF) on bone healing around implants placed in elevated sinus cavities. Forty New Zealand albino rabbits were divided into eight groups, based on the time of sacrifice (14 or 40 days) and the material used: blood clot (control), hydroxyapatite (HA) from bovine bone, HA combined with PRF, and PRF alone. Each group consisted of five animals (n = 5). A histological analysis measured bone-to-implant contact (BIC) and bone area fraction occupancy (BAFO). The results showed significant increases in the BIC and BAFO values at 40 days compared to 14 days in most groups. At day 14, the HA+PRF group had higher BIC than the clot and the PRF alone groups. At 40 days, HA+PRF maintained the highest BIC across all groups (p < 0.05), though it did not show an advantage for BAFO. These findings indicate that combining HA with PRF promotes better osseointegration around implants placed immediately in maxillary sinus augmentation. Given the limited research on PRF’s biological impact, these results underscore the importance of evaluating PRF’s role in peri-implant healing and its potential benefits for clinical use in sinus augmentation. Full article
(This article belongs to the Special Issue New Biomaterials in Periodontology and Implantology)
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14 pages, 3210 KiB  
Article
Evaluation of the Peri-Implant Tissues of Patients with Severe Bone Atrophy Treated with a New Short and Extra-Short Implant System—A Pilot Study
by Kely Cristina de Moraes, Geninho Thomé, Flávia Noemy Gasparini Kiatake Fontão, Carolina Accorsi Cartelli, Rosemary Adriana Chierici Marcantonio, Carolina Mendonça de Almeida Malzoni and Elcio Marcantonio Junior
J. Funct. Biomater. 2024, 15(10), 288; https://doi.org/10.3390/jfb15100288 - 29 Sep 2024
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Abstract
This study aimed to assess clinical and radiographic outcomes, including implant survival, marginal bone loss, and patient satisfaction, in individuals with severe bone atrophy treated using a newly developed system of short and extra-short implants. A total of 44 implants (37 short and [...] Read more.
This study aimed to assess clinical and radiographic outcomes, including implant survival, marginal bone loss, and patient satisfaction, in individuals with severe bone atrophy treated using a newly developed system of short and extra-short implants. A total of 44 implants (37 short and 7 extra-short) were placed with immediate loading in 11 patients. The patients were followed up at between 6 and 24 months. Bone changes, keratinized mucosa, bleeding on probing, probing depth, crown-to-implant ratio, and patient satisfaction were evaluated. An implant survival and success rate of 100% was observed. The peri-implant bone condition showed no significant associations between marginal bone loss (MBL) and gingival recession. In extra-short implants, the crown-to-implant ratio did not affect MBL in the evaluated times. However, short implants showed a statistically significant inverse correlation between mesial measurement and crown-to-implant ratio (p = 0.006) and between distal measurement and crown-to-implant ratio (p = 0.004) over six months. Plaque was present in the mesiobuccal regions in 38.64% of the implants, with extra-short implants having the highest relative frequency (71.4%). Bleeding was observed in 18.9% of the short implants in the mesiolingual region and 14.3% of the extra-short implants. There was a statistically significant association between bleeding on probing in the mesiobuccal region and the type of implant (p = 0.026). The analysis of probing depth showed no difference between the types of implants. Within the limits of this study, short and extra-short implants presented similar clinical and radiographic behavior of soft and hard tissues in the evaluated times. Full article
(This article belongs to the Special Issue New Biomaterials in Periodontology and Implantology)
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Other

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29 pages, 1949 KiB  
Systematic Review
Patient Experience and Wound Healing Outcomes Using Different Palatal Protection Methods After Free Gingival Grafts: A Systematic Review
by Tomasz Jankowski, Agnieszka Jankowska, Mirona Palczewska-Komsa, Maciej Jedliński, Wojciech Kazimierczak and Joanna Janiszewska-Olszowska
J. Funct. Biomater. 2024, 15(12), 360; https://doi.org/10.3390/jfb15120360 - 27 Nov 2024
Viewed by 1462
Abstract
(1) Background: A free gingival graft (FGG) is a common technique used to reconstruct or enhance the area of keratinized mucosa, while a connective tissue graft (CTG) is utilized to boost soft tissue thickness, thereby promoting stability in interproximal marginal bone levels. Most [...] Read more.
(1) Background: A free gingival graft (FGG) is a common technique used to reconstruct or enhance the area of keratinized mucosa, while a connective tissue graft (CTG) is utilized to boost soft tissue thickness, thereby promoting stability in interproximal marginal bone levels. Most reported complications following FGG procedure are associated with the donor site. In addition to a painful, open wound in the palate, the most frequent complications linked to FGG harvesting include excessive bleeding, postoperative bone exposure, and recurrent herpes lesions. Numerous methods for securing the donor site after a free gingival graft surgery have been documented in research publications. The main objective of this systematic review was to assess various techniques for protecting the palate after graft harvesting and their impact on patient experience, with a focus on pain management. The secondary objective was to evaluate these techniques in relation to donor site wound healing. (2) Methods: The search was performed across four databases: Medline (PubMed Central), Scopus, Web of Science, and Embase, in accordance with PRISMA guidelines and the recommendations set forth in the Cochrane Handbook for Systematic Reviews of Interventions. The initial search took place on 9 October 2023, followed by an update on 28 June 2024. The search utilized the following keywords: (“wound” OR “injury”) AND (“graft” OR “free gingival graft” OR “graft harvesting”) AND (“healing” OR “recovery”) AND “palate”. (3) Results: After conducting the follow-up search, a total of 958 papers were identified: 193 from PubMed, 314 from Scopus, 101 from Web of Science, and 350 from Embase. Ultimately, of the 49 papers that remained, 11 were excluded due to not fulfilling the inclusion criteria, leaving 38 full-text papers on free gingival grafts (FGG) for qualitative analysis. (4) Conclusions: Various methods for palatal protection after free gingival grafts (FGG) are described in the literature, stemming from biological, physical, or chemical sources. Most studies in this review examined platelet-rich fibrin and suggested that it provides no benefits for patients’ subjective experiences or wound healing outcomes. While photobiomodulation appears to support wound epithelialization, it does not influence pain perception. Alternatives such as propolis, hyaluronic acid, and medicinal plant extracts show potential for palatal protection; however, further research is needed to thoroughly evaluate their effectiveness. Full article
(This article belongs to the Special Issue New Biomaterials in Periodontology and Implantology)
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