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Multidisciplinary Therapeutic Strategies in Head and Neck Surgery
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Multidisciplinary Therapeutic Strategies in Head and Neck Surgery

A special issue of Journal of Personalized Medicine (ISSN 2075-4426). This special issue belongs to the section "Clinical Medicine, Cell, and Organism Physiology".

Deadline for manuscript submissions: closed (27 February 2024) | Viewed by 7188

Special Issue Editors

Dr. Salvatore Crimi

E-Mail Website
Guest Editor
Maxillo Facial Unit, University Hospital “Policlinico San Marco” of Catania, 95124 Catania, Italy
Interests: oral surgery; oral cancers; head and neck cancers; cutaneous lesions; head and neck trauma
Special Issues, Collections and Topics in MDPI journals
Prof. Dr. Gabriele Cervino

E-Mail Website
Guest Editor
Department of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina-Policlinico "Gaetano Martino”, Via Consolare Valeria, 98100 Messina, Italy
Interests: biomaterials; oral surgery; implantology; oral pathology; prosthodontics; bioengineering
Special Issues, Collections and Topics in MDPI journals
Dr. Riccardo Nocini

E-Mail Website
Guest Editor
Unit of ENT, Department of Surgical Sciences, Dentistry, Gynecology and Pediatrics, University of Verona, 37124 Verona, Italy
Interests: head and neck microsurgery; piezoelectric surgery; otolaryngology procedures; craniofacial malformations; head and neck microsurgery; sleep apnea syndrome
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Due to its anatomical complexity, head and neck surgery is increasingly becoming a multidisciplinary pathology. Because of the multifunctional anatomical intricacies of the head and neck, disease progression and therapy-related side effects often severely affect the patient’s appearance and self-image, as well as their ability to breathe, speak, and swallow. In present times, head and neck pathologies require a combination of multiples specialties working together, from the easy and basic affections of the oral cavity (such as odontogenic cyst, rhinosinusitis, dentofacial malformation, OSAS, and MRONJ) to more complex situations, such as epithelial malignancies of the upper aerodigestive tract (nasal cavity, oral cavity, oropharynx, pharynx, hypopharynx, and larynx), cutaneous malignancies of the head and neck region, and malignant tumors arising from different cell types of the thyroid and salivary glands, as well as simple and complex traumas. The enlistment of patients involves various specialists, such us oral surgeons, maxillofacial surgeons, head and neck surgeons, and dermatologists, as well as prosthodontists. An aim of providing the final recovery of aesthetics and functions throughout a close cooperation of different medical specialists should be a requirement of head and neck surgery. It is almost of gold standard that these patients need personalized treatment strategies involving all the mentioned specialties in a multidisciplinary approach. These factors make both head and neck surgery and its management especially difficult for patients, as well as motivating us to develop the field forward to create a “tailor made” solution from a multidisciplinary perspective.

Areas in particular need of novel insights include the treatment of recurrent and metastatic disease and the personalization of treatment based on the molecular characteristics of individual tumors.

For the above reasons, in this Special Issue, we welcome clinical research papers, basic translational professional opinions, and reviews in the broad field of multidisciplinary therapeutic surgical and rehabilitative strategies in head and neck surgery.

Dr. Salvatore Crimi
Prof. Dr. Gabriele Cervino
Dr. Riccardo Nocini
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Personalized Medicine is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

 

Keywords

  • head and neck surgery
  • oral surgery
  • multidisciplinary approach
  • Oral Maxillo Facial surgery
  • Rehabilitative strategies
  • oral oncology
  • oral cancers
  • trauma
  • ENT durgery
  • OSAS
  • dento-facial deformities
  • orthognatic surgery

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Published Papers (3 papers)

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Research

13 pages, 3593 KiB  
Article
Pretreatment Tumor Volume and Tumor Sphericity as Prognostic Factors in Patients with Oral Cavity Squamous Cell Carcinoma: A Prospective Clinical Study in 95 Patients
by Elisabetta Lucchi, Laura Cercenelli, Vincenzo Maiolo, Barbara Bortolani, Emanuela Marcelli and Achille Tarsitano
J. Pers. Med. 2023, 13(11), 1601; https://doi.org/10.3390/jpm13111601 - 13 Nov 2023
Viewed by 1042
Abstract
The prognostic impact of tumor volume and tumor sphericity was analyzed in 95 patients affected by oral cancer. The pre-operative computed tomography (CT) scans were used to segment the tumor mass with threshold tools, obtaining the corresponding volume and sphericity. Events of recurrence [...] Read more.
The prognostic impact of tumor volume and tumor sphericity was analyzed in 95 patients affected by oral cancer. The pre-operative computed tomography (CT) scans were used to segment the tumor mass with threshold tools, obtaining the corresponding volume and sphericity. Events of recurrence and tumor-related death were detected for each patient. The mean follow-up time was 31 months. A p-value of 0.05 was adopted. Mean tumor volume resulted higher in patients with recurrence or tumor-related death at the Student’s t-test (respectively, 19.8 cm3 vs. 11.1 cm3, p = 0.03; 23.3 cm3 vs. 11.7 cm3, p = 0.02). Mean tumor sphericity was higher in disease-free patients (0.65 vs. 0.59, p = 0.04). Recurrence-free survival and disease-specific survival were greater for patients with a tumor volume inferior to the cut-off values of 21.1 cm3 (72 vs. 21 months, p < 0.01) and 22.4 cm3 (85 vs. 32 months, p < 0.01). Recurrence-free survival and disease-specific survival were higher for patients with a tumor sphericity superior to the cut-off value of 0.57 (respectively, 49 vs. 33 months, p < 0.01; 56 vs. 51 months, p = 0.01). To conclude, tumor volume and sphericity, three-dimensional parameters, could add useful information for better stratification of prognosis in oral cancer. Full article
(This article belongs to the Special Issue Multidisciplinary Therapeutic Strategies in Head and Neck Surgery)
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14 pages, 7438 KiB  
Article
Tongue Reconstruction with Buccinator Myomucosal Island Flaps: Technical Considerations, Oncologic Safety, Functional Outcomes and QoL Assessment—A Retrospective Observational Study
by Olindo Massarelli, Luigi Angelo Vaira, Salvatore Crimi, Giovanni Salzano, Linda Latini, Alberto Bianchi, Paolo Gennaro and Giacomo De Riu
J. Pers. Med. 2023, 13(6), 879; https://doi.org/10.3390/jpm13060879 - 23 May 2023
Cited by 2 | Viewed by 2590
Abstract
The objective of this study was to investigate the effectiveness of buccinator myomucosal island flaps for tongue reconstruction following malignant tumor resections. A retrospective study was performed on 52 patients who underwent tongue reconstructions with buccinator myomucosal island flaps between 2012 and 2020. [...] Read more.
The objective of this study was to investigate the effectiveness of buccinator myomucosal island flaps for tongue reconstruction following malignant tumor resections. A retrospective study was performed on 52 patients who underwent tongue reconstructions with buccinator myomucosal island flaps between 2012 and 2020. We reviewed the flap type and size, harvesting time, recipient- and donor-site complications, postoperative oncologic outcomes, functional recovery and QoL assessment. All of the flaps were transposed successfully without any total flap loss. Neither in the primary site nor in the neck were cancer relapses observed. An evaluation of the sensitivity revealed that 96.1% of patients experienced a recovery of touch, two-point and pain sensations. There were significant differences between the flap and the native mucosa in terms of the tactile (p < 0.001), pain (p < 0.001) and two-point (p < 0.001) thresholds. The average swallowing score recorded was 6.1 out of 7, with only minor complaints. The quality of life assessments demonstrated high scores across physical (24.5 out of 28), social (25.8 out of 28), emotional (20.3 out of 24) and functional (25 out of 28) aspects. The present study showed how buccinator myomucosal island flaps represent an effective and functional tongue reconstructive option, requiring a short operative time with a low rate of donor site morbidity, and with evidence of long-term oncologic safety and high quality of life. Full article
(This article belongs to the Special Issue Multidisciplinary Therapeutic Strategies in Head and Neck Surgery)
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12 pages, 1056 KiB  
Article
A Single-Center Retrospective Analysis of 14 Head and Neck AVMs Cases Treated with a Single-Day Combined Endovascular and Surgical Approach
by Paolo Gennaro, Samuele Cioni, Sandra Bracco, Flavia Cascino, Linda Latini, Manfredi Abbagnato, Olindo Massarelli and Guido Gabriele
J. Pers. Med. 2023, 13(5), 757; https://doi.org/10.3390/jpm13050757 - 28 Apr 2023
Cited by 2 | Viewed by 2468
Abstract
Arteriovenous malformations (AVMs) are rare congenital defects of vascular development whose treatment remains challenging. The paper presents a retrospective single-center study of 14 patients with AVMs of the head and neck region undergoing combined endovascular and surgical treatment in a single day. AVM [...] Read more.
Arteriovenous malformations (AVMs) are rare congenital defects of vascular development whose treatment remains challenging. The paper presents a retrospective single-center study of 14 patients with AVMs of the head and neck region undergoing combined endovascular and surgical treatment in a single day. AVM architecture and therapeutic strategies were determined on the basis of angiographic studies, while the psychological involvement of each patient was assessed by means of a questionnaire. Most of the 14 patients achieved satisfactory clinical results with no recurrences, good aesthetic and functional results, and most patients reported improved quality of life. The combined endovascular and surgical approach is an effective treatment for AVMs of the head and neck and performing it on the same day is a possible option often accepted by patients which guarantees operative advantages for the surgeon. Full article
(This article belongs to the Special Issue Multidisciplinary Therapeutic Strategies in Head and Neck Surgery)
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