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Life
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Advanced Endoscopy in the Treatment of Complications after Gastrointestinal Surgery
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Advanced Endoscopy in the Treatment of Complications after Gastrointestinal Surgery

A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Medical Research".

Deadline for manuscript submissions: closed (31 October 2024) | Viewed by 5215

Special Issue Editors

Dr. Francesco Vito Mandarino

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Guest Editor
Department of Gastroenterology and Gastrointestinal Endoscopy, IRCCS San Raffaele Hospital, Vita-Salute San Raffaele University, Scientific Institute San Raffaele, 20132 Milan, Italy
Interests: operative endoscopy; luminal endoscopy; gastroparesis; post-surgical endoscopic treatment; sedation; surgical endoscopy
Special Issues, Collections and Topics in MDPI journals
Dr. Emanuele Sinagra

E-Mail Website
Guest Editor
Gastroenterology and Endoscopy Unit, Fondazione Istituto Giuseppe Giglio, Contrada Pietra Pollastra Pisciotto, 90015 Cefalù, Italy
Interests: gastroenterology; gastrointestinal endoscopy; irritable bowel syndrome; inflammatory bowel disease; ERCP; EUS
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

In recent years, advanced endoscopy has emerged as an effective and minimally invasive treatment for complications following major gastrointestinal surgery. The integration of endoscopic vacuum therapy, stents and OTSC into clinical practice has shown promising results in managing anastomotic leaks in both the lower and upper digestive tracts. Presently, there is a need for additional data to validate the existing evidence and develop precise treatment algorithms. This Special Issue is calling for paper submissions focusing on the endoscopic treatment of gastrointestinal post-surgical complications, including leaks and bleeding. The objective is to present further evidence and reinforce the notion of endoscopy as a frontline approach in treating such complications, thereby enhancing patient outcomes.

You may choose our Joint Special Issue in Gastroenterology Insights.

Dr. Francesco Vito Mandarino
Dr. Emanuele Sinagra
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Life is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • advanced endoscopy
  • complications
  • surgery
  • anastomotic leak

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Related Special Issue

Published Papers (3 papers)

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Editorial

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4 pages, 184 KiB  
Editorial
The Triple-S Advantage of Endoscopic Management in Gastrointestinal Surgery Complications: Safe, Successful, and Savings-Driven
by Francesco Vito Mandarino, Emanuele Sinagra, Alberto Barchi and Silvio Danese
Life 2024, 14(1), 122; https://doi.org/10.3390/life14010122 - 15 Jan 2024
Cited by 1 | Viewed by 1148
Abstract
Despite advances in gastrointestinal (GI) surgery, post-operative complications are not entirely avoidable [...] Full article
(This article belongs to the Special Issue Advanced Endoscopy in the Treatment of Complications after Gastrointestinal Surgery)

Review

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10 pages, 764 KiB  
Review
VacStent as an Innovative Approach in the Treatment of Anastomotic Insufficiencies and Leakages in the Gastrointestinal Tract—Review and Outlook
by Alexander Yohannes, Judith Knievel, Jonas Lange, Arno J. Dormann, Ulrich Hügle, Claus F. Eisenberger and Markus M. Heiss
Life 2024, 14(7), 821; https://doi.org/10.3390/life14070821 - 27 Jun 2024
Viewed by 1157
Abstract
Anastomotic insufficiencies are severe complications of abdominal surgery, often leading to prolonged hospitalization, serious tissue inflammation, and even sepsis, along with the need for recurrent surgery. Current non-surgical treatments such as self-expanding metal stents (SEMSs) and endoscopic vacuum therapy (EVT) have limitations, including [...] Read more.
Anastomotic insufficiencies are severe complications of abdominal surgery, often leading to prolonged hospitalization, serious tissue inflammation, and even sepsis, along with the need for recurrent surgery. Current non-surgical treatments such as self-expanding metal stents (SEMSs) and endoscopic vacuum therapy (EVT) have limitations, including stent migration or perforation. This review evaluates the effectiveness of the VacStent GITM (Möller Medical GmbH, Fulda, Germany), a novel medical device combining SEMS and negative-pressure wound therapy in treating gastrointestinal leaks. Data were gathered from four prospective studies and compared with existing treatments. Studies on the VacStent GITM application demonstrate technical success and competitive closure rates in upper gastrointestinal leaks, with minimal complications reported. Comparative analyses with SEMS and EVT reveal promising and most importantly equally good outcomes while maintaining the possibility for sustained enteral nutrition and reducing the risk of stent migration. The VacStent GITM presents a promising alternative to current non-surgical treatments. Ongoing research aims to validate its efficacy in lower gastrointestinal leaks and comprehensively establish its role in leak management. Further investigation is necessary to confirm these findings and optimize treatment protocols. Future usages of the VacStent GITM in colonic anastomotic insufficiencies promise an effective approach and might be able to lower the rates of necessary implementations of a stoma. Full article
(This article belongs to the Special Issue Advanced Endoscopy in the Treatment of Complications after Gastrointestinal Surgery)
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Other

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14 pages, 1316 KiB  
Systematic Review
Hiatal Hernias Revisited—A Systematic Review of Definitions, Classifications, and Applications
by Karl Hermann Fuchs, Ioannis Kafetzis, Alexander Hann and Alexander Meining
Life 2024, 14(9), 1145; https://doi.org/10.3390/life14091145 - 11 Sep 2024
Cited by 1 | Viewed by 2366
Abstract
Introduction: A hiatal hernia (HH) can be defined as a condition in which elements from the abdominal cavity herniate through the oesophageal hiatus in the mediastinum and, in the majority of cases, parts of the proximal stomach. Today, the role of HHs within [...] Read more.
Introduction: A hiatal hernia (HH) can be defined as a condition in which elements from the abdominal cavity herniate through the oesophageal hiatus in the mediastinum and, in the majority of cases, parts of the proximal stomach. Today, the role of HHs within the complex entity of gastroesophageal reflux disease (GERD) is very important with regard to its pathophysiology, severity, and therapeutic and prognostic options. Despite this, the application and stringent use of the worldwide accepted classification (Skinner and Belsey: Types I–IV) are lacking. The aim of this study was to carry out a systematic review of the clinical applications of HH classifications and scientific documentation over time, considering their value in diagnosis and treatment. Methods: Following the PRISMA concept, all abstracts published on pubmed.gov until 12/2023 (hiatal hernia) were reviewed, and those with a focus and clear description of the application of the current HH classification in the full-text version were analysed to determine the level of classification and its use within the therapeutic context. Results: In total, 9342 abstracts were screened. In 9199 of the abstracts, the reports had a different focus than HH, or the HH classification was not used or was incompletely applied. After further investigation, 60 papers were used for a detailed analysis, which included more than 12,000 patient datapoints. Among the 8904 patients, 83% had a Type I HH; 4% had Type II; 11% had Type III; and 1% had Type IV. Further subgroup analyses were performed. Overall, the precise application of the HH classification has been insufficient, considering that only 1% of all papers and only 54% of those with a special focus on HH have documented its use. Conclusions: The application and documentation of a precise HH classification in clinical practice and scientific reports are decreasing, which should be rectified for the purpose of scientific comparability. Full article
(This article belongs to the Special Issue Advanced Endoscopy in the Treatment of Complications after Gastrointestinal Surgery)
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