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Veterinary Pathology and Veterinary Anatomy: 2nd Edition
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Veterinary Pathology and Veterinary Anatomy: 2nd Edition

A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Animal Science".

Deadline for manuscript submissions: closed (31 October 2024) | Viewed by 12526

Special Issue Editors

Prof. Dr. Carmen Solcan

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Guest Editor
Histology and Molecular Biology, Department of Preclinics, Ion Ionescu de la Brad University of Life Sciences, Mihail Sadoveanu Alley, No. 8, 700489 Iasi, Romania
Interests: veterinary medicine; veterinary pathology; veterinary anatomy; animals
Special Issues, Collections and Topics in MDPI journals
Prof. Dr. Gheorghe Solcan

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Guest Editor
Internal Medicine Unit, Clinics Department, Faculty of Veterinary Medicine, Iași University of Life Sciences Ion Ionescu de la Brad, Iasi, Romania
Interests: veterinary medicine; internal medicine; toxicology; dermatology
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

This second volume of the Special Issue “Veterinary Pathology and Veterinary Anatomy” builds upon the success of the first. Authors are encouraged to submit their research for publication in this edition (https://www.mdpi.com/journal/life/special_issues/S5REQE7J13).

This Special Issue of Life titled “Veterinary Pathology and Veterinary Anatomy” is dedicated to the study of veterinary disease and physiology and encompasses various aspects of pathology in domestic and wild animals, such as the following:

- New challenges for veterinary pathology in the context of the SARS-CoV2 pandemic; animals as potential reservoirs for SARS-CoV2 and for other potential pandemics;
- New challenges for veterinary pathology induced by climate change and the spread of tropical diseases in the northern hemisphere;
- Challenges for pathology induced by armed conflicts;
- Diseases transmissible from animals to humans and from wild to domestic animals and means of prevention. Animal pandemics have major economic and social impacts: African Swine Fever, Avian Influenza, Ruminant Pest, etc.
- Diseases caused by industrial toxins, environmental pollution, and mycotoxins (current state of pathogenetic mechanisms, diagnosis, and means of prevention);
- Epidemiology of non-communicable diseases concerning environmental pollution (allergies, cancer, and degenerative diseases).

This Special Issue also focuses on new developments in diagnosing and treating animal diseases. Original manuscripts covering various aspects of veterinary pathology are requested. Papers reporting new solutions to common problems and new descriptions of lesser-recognized conditions are particularly welcome. In addition, we encourage papers detailing advanced diagnostic techniques, the use of microscopic anatomy in diagnosis, and computer modeling of pathological processes.

Prof. Dr. Carmen Solcan
Prof. Dr. Gheorghe Solcan
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Life is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • veterinary pathology
  • veterinary anatomy
  • SARS-CoV2 pandemic
  • climate change
  • environmental pollution
  • diagnosis and treatment of animal diseases
  • computer modeling of pathological processes

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Published Papers (12 papers)

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13 pages, 2474 KiB  
Article
Thermographic Scan of the Thoracolumbar Area in Dogs with Acute Intervertebral Disc Extrusion (IVDE): A Retrospective Study
by Cristian Zaha, Liliana Cărpinișan, Larisa Schuszler, Nistor Paula, Tudor Căsălean, Tiana Florea, Văduva Cristina, Bogdan Sicoe, Ciprian Rujescu and Roxana Dascălu
Life 2025, 15(1), 68; https://doi.org/10.3390/life15010068 - 9 Jan 2025
Viewed by 751
Abstract
Background: several authors have documented variations in local temperature in both horses and dogs presenting acute intervertebral disc extrusion (IVDE) along the entire spinal column. However, none have demonstrated distinct temperature differences between healthy animals and those with IVDE. A retrospective study was [...] Read more.
Background: several authors have documented variations in local temperature in both horses and dogs presenting acute intervertebral disc extrusion (IVDE) along the entire spinal column. However, none have demonstrated distinct temperature differences between healthy animals and those with IVDE. A retrospective study was conducted to assess the efficacy of thermography at evaluating local temperature and thermal patterns in healthy dogs as well in those with IVDE across the T11–L3 area. Methods: the study included 20 healthy dogs and 32 dogs with IVDE. For both groups of dogs, the thoracolumbar region was trimmed and, subsequently, scanned using the Flir E50 thermography device. The Flir Tool software was used to analyze three designated areas (Bx1, Bx2, Bx3) within the thoracolumbar region by comparing the average temperature of the minimum, maximum, and mean temperature recordings between the two groups. Results: the thermal pattern and the local temperature of the thoracolumbar area present differences between healthy dogs and those with IVDE. Conclusions: we recommend thermographic scanning of the thoracolumbar area to find differences in local temperature between healthy dogs and those with intervertebral disc extrusion. Further investigations are required to differentiate between disc extrusion that exhibits lateralization to the right or left. Full article
(This article belongs to the Special Issue Veterinary Pathology and Veterinary Anatomy: 2nd Edition)
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10 pages, 1810 KiB  
Article
Ureteral Closure Using Advanced Bipolar Vessel Sealing Devices During Laparoscopic Nephrectomy in Dogs and Cats: A Pilot Series of Clinical Cases
by Przemysław Prządka, Bartłomiej Liszka, Kamil Suliga, Agnieszka Antończyk, Zdzisław Kiełbowicz, Dominika Kubiak-Nowak, Stanisław Dzimira, Adam Skalski and Ludwika Gąsior
Life 2024, 14(12), 1681; https://doi.org/10.3390/life14121681 - 18 Dec 2024
Viewed by 580
Abstract
Recently, laparoscopic nephrectomy has become more popular in veterinary medicine. In the majority of these procedures, vascular sealing devices (VSDs) are used. These allow for the closure of renal vessels with advanced bipolar coagulation. However, until now, closure of the ureter was performed [...] Read more.
Recently, laparoscopic nephrectomy has become more popular in veterinary medicine. In the majority of these procedures, vascular sealing devices (VSDs) are used. These allow for the closure of renal vessels with advanced bipolar coagulation. However, until now, closure of the ureter was performed with mechanical clips or suturing. There is a lack of information in the literature about the possibility of VSDs being used for ureter closure. This article presents the possibility of renal vessels and ureter closure in cats and dogs with vascular sealing devices. Laparoscopic nephrectomy in dogs and cats was performed entirely with VSDs. Patients with unilateral hydronephrosis qualified for the procedure. The nephrectomies were completely performed using a laparoscopic approach. Both renal vasculature and ureter were closed with VSDs. Additionally, two resected ureters from operated cats underwent histopathological evaluation. Among the operated animals, there were no postoperative complications or signs in the urinary tract. Histopathological evaluation of two cats’ ureters showed lumen closure on the coagulation places. Vascular sealing devices, during laparoscopic nephrectomy, allow for closure of not only the renal vessels but also ureters. Full article
(This article belongs to the Special Issue Veterinary Pathology and Veterinary Anatomy: 2nd Edition)
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7 pages, 2949 KiB  
Article
Effect of Hot Water Bottle and Cloth Blanket on Rectal Temperature During Magnetic Resonance Imaging of the Head in Cats Under General Anesthesia
by Ruxandra Pavel, Cristina Fernoagă, Alexandru Gabriel Neagu and Ruxandra Costea
Life 2024, 14(12), 1646; https://doi.org/10.3390/life14121646 - 11 Dec 2024
Viewed by 605
Abstract
Maintaining an animal’s body temperature during magnetic resonance imaging (MRI) poses great challenges, as many temperature measuring devices and warming systems are incompatible with the MRI machine. The aim of this study was to examine body temperature changes and evaluate the impact of [...] Read more.
Maintaining an animal’s body temperature during magnetic resonance imaging (MRI) poses great challenges, as many temperature measuring devices and warming systems are incompatible with the MRI machine. The aim of this study was to examine body temperature changes and evaluate the impact of using a hot water bottle and a cloth blanket on rectal temperature during magnetic resonance imaging in cats. We included in this study 30 cats from different breeds that underwent magnetic resonance imaging for 60 min that were randomly divided into a passively insulated group (G1) covered with a blanket (n = 15) and a positively heated group (G2) using a silicone hot water bottle under the abdomen and the same cloth blanket over the cat (n = 15). The body temperature was measured before premedication, before induction of anesthesia, and after the MRI examination. Body temperature decreased slightly but significantly (p < 0.05) after premedication. At the end of the MRI, body temperature had decreased more in G1 than G2 (p = 0.033) to 37.0 (36.5–37.5) °C and 38 (37.9–38.2) °C, respectively. This study provides clinical evidence that cats needing magnetic resonance imaging of the head can be protected from hypothermia by using a hot water bottle placed underneath their abdomen and a cloth blanket covering their full body. Full article
(This article belongs to the Special Issue Veterinary Pathology and Veterinary Anatomy: 2nd Edition)
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14 pages, 1972 KiB  
Article
Detection of Ochratoxin A in Maize and Its Potential Impact on Avian Pathology in Romanian Farms
by Silviu-Ionut Beia, Violeta Alexandra Ion, Elvira Gagniuc, Oana-Crina Bujor, Elena Ştefania Ivan, Andreea Barbu, Elena Pitoiu, Violeta Elena Beia and Liliana Bădulescu
Life 2024, 14(11), 1477; https://doi.org/10.3390/life14111477 - 13 Nov 2024
Viewed by 740
Abstract
Ochratoxin A (OTA) is a nephrotoxic mycotoxin that commonly contaminates maize, posing significant health risks to both poultry and humans. In this study, a rapid and sensitive method utilizing ultra-performance liquid chromatography coupled with fluorescence detection (UPLC-FLD) was developed for the quantification of [...] Read more.
Ochratoxin A (OTA) is a nephrotoxic mycotoxin that commonly contaminates maize, posing significant health risks to both poultry and humans. In this study, a rapid and sensitive method utilizing ultra-performance liquid chromatography coupled with fluorescence detection (UPLC-FLD) was developed for the quantification of OTA levels in maize. The method utilizes immunoaffinity column purification for improved specificity. Accuracy and precision were validated in line with European Union Reference Laboratory (EURL-MP) guidelines, meeting regulatory standards for linearity, trueness, detection and quantification limits, precision, and uncertainty, as per European Commission Regulation (EC) No. 401/2006 and its amendments. The method demonstrated an average recovery rate of 116.78% for maize, with RSDwR values (within-laboratory reproducibility) of 12.72%. Furthermore, OTA occurrence and its possible effects were investigated in several farms in South Romania, where necropsy and histopathological analyses of poultry revealed severe kidney damage, including renal tubular degeneration. Full article
(This article belongs to the Special Issue Veterinary Pathology and Veterinary Anatomy: 2nd Edition)
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10 pages, 1597 KiB  
Article
Correlation Between Hyperlipidemia-Related Diseases and Thorax/Thigh Circumference Ratio Along with Body Condition Score in Dogs Focusing on Molecular Mechanism: A Pilot Study and Literature Review
by Kyuhyung Choi
Life 2024, 14(11), 1441; https://doi.org/10.3390/life14111441 - 7 Nov 2024
Viewed by 903
Abstract
There are some limitations to using the body condition score (BCS) for client education to prevent obesity, hyperlipidemia-related diseases, and orthopedic diseases in dogs because it is hard to quantify in detail. Especially in small dogs, patellar luxation is a common orthopedic disease [...] Read more.
There are some limitations to using the body condition score (BCS) for client education to prevent obesity, hyperlipidemia-related diseases, and orthopedic diseases in dogs because it is hard to quantify in detail. Especially in small dogs, patellar luxation is a common orthopedic disease that is related to obesity and the hind leg muscle. In this pilot study, the author evaluated the thorax/thigh circumference ratio as a prognostic evaluation index, along with the BCS, for assessing patellar dislocation and other hyperlipidemia-related diseases and states such as hypertriglyceridemia and obesity-related orthopedic disease in small dogs. Eleven client-owned dogs were selected randomly among patients that visited Bundang New York Animal Hospital, South Korea from June 2021 to August 2024. According to the results, triglycerides (TG) showed a negative correlation with thorax/thigh value (R = −0.585, p-value = 0.059) and a strong positive correlation with thigh circumference (R = 0.749, p-value = 0.008). Total cholesterol (TC) showed a strong positive correlation with thigh circumference (R = 0.776, p-value = 0.005), whereas the thorax/thigh value showed a negative correlation with the medial patella luxation (MPL) grade with low significance (R = −0.343, p-value = 0.302). These data indicate that thigh circumference can be an excellent negative indicator for hyperlipidemia and thorax/thigh value shows no correlation with medial patella luxation, which has many factors such as varus and trochlear groove. Despite the limitations of this study due to the small sample size, this pilot study is significant as it is the first trial to introduce a new indicator for monitoring hyperlipidemia at home by using a simple tape measure. Also, the author reviews molecular pathways including the ApoA-1, ApoE, and LPL genes, which are related to hyperlipidemia, to explain the results. Full article
(This article belongs to the Special Issue Veterinary Pathology and Veterinary Anatomy: 2nd Edition)
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23 pages, 7262 KiB  
Article
The Gross Anatomical and Histological Features of the Humerus in African Green Monkeys (Chlorocebus sabaeus) from Saint Kitts and Nevis, West Indies
by Cristian Olimpiu Martonos, Alexandru Ion Gudea, William Brady Little, Florin Gheorghe Stan, Călin Lațiu, Pompei Bolfa and Cristian Constantin Dezdrobitu
Life 2024, 14(10), 1295; https://doi.org/10.3390/life14101295 - 12 Oct 2024
Cited by 1 | Viewed by 889
Abstract
This paper presents a detailed gross description of all anatomical elements of the humerus in the African green monkey and provides comparative and differential elements on monkey osteology. The osteometric investigation adds value to the gross morphological investigation, adjoining metric data to the [...] Read more.
This paper presents a detailed gross description of all anatomical elements of the humerus in the African green monkey and provides comparative and differential elements on monkey osteology. The osteometric investigation adds value to the gross morphological investigation, adjoining metric data to the gross descriptive data set. An in-depth investigation of the microstructural aspects of the humeral bone tissue is provided, with qualitative and quantitative details and potential for diagnostic applications. Of the gross morphological elements described, several unique features specific to this species include the humeral head shape that presents with distinctive low convexity and caudal placement, the shape of the intertubercular groove, the less developed greater tubercle, and the disposition of the rotator cuff muscle insertion. Furthermore, the overall cranio-lateral curvature of the bone shaft was found to have a distinctive 154–155 degree of angulation of the diaphysis, and the well-developed medial epicondyle was observed with its distinctive medio-caudal retroflexion. The histological investigation was more indicative of a typical non-primate organization of the bone tissue, with laminar vascular and avascular structures combined with the presence of the secondary Haversian system involving a mixture of scattered and dense unorganized secondary osteonal structures. The histomorphometric investigation yielded metrical data for the secondary osteonal structures in terms of area (20,331 ± 5105 µm2), perimeter, and vascular canal area (64,769 ± 257 µm2). Full article
(This article belongs to the Special Issue Veterinary Pathology and Veterinary Anatomy: 2nd Edition)
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9 pages, 1228 KiB  
Article
Computed Tomography and Fluorescence Spectroscopy Blood Plasma Analysis Study for Kynurenic Acid as a Diagnostic Approach to Chronic Coenurosis in Sheep
by Loredana Elena Olar, Vasile Daniel Tomoiagă, Sorin Marian Mârza, Ionel Papuc, Ioan Florin Beteg, Petru Cosmin Peștean, Mihai Musteață, Caroline Maria Lăcătuș, Raluca Marica, Paula Maria Pașca, Robert Cristian Purdoiu and Radu Lăcătuș
Life 2024, 14(9), 1121; https://doi.org/10.3390/life14091121 - 5 Sep 2024
Viewed by 1046
Abstract
Coenurosis is a parasitic disease caused by the larval stage of Taenia multiceps, Coenurus cerebralis, typically found in the central nervous system of different livestock such as sheep and goats. The blood plasma from fifteen clinically healthy sheep and six sheep [...] Read more.
Coenurosis is a parasitic disease caused by the larval stage of Taenia multiceps, Coenurus cerebralis, typically found in the central nervous system of different livestock such as sheep and goats. The blood plasma from fifteen clinically healthy sheep and six sheep with neurological symptoms was studied by fluorescence spectroscopy in order to establish the contribution of kynurenic acid (KYNA), the neuroprotective metabolite of the kynurenine pathway, to the total fluorescence of the plasma. CT scans were used to confirm the presence of cysts in the central nervous system of sheep with neurological symptoms. The fluorescence spectroscopy analysis and further spectra deconvolution process revealed some significantly lower KYNA contributions to the total plasma fluorescence in sheep with coenurosis compared to healthy controls. Our results indicate that KYNA emission parameters could serve as valuable diagnostic markers, particularly for detecting preclinical cases of coenurosis, thus allowing for improved farm management practices. Full article
(This article belongs to the Special Issue Veterinary Pathology and Veterinary Anatomy: 2nd Edition)
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21 pages, 6002 KiB  
Article
Evaluation of Biocomposite Cements for Bone Defect Repair in Rat Models
by Alina Ioana Ardelean, Sorin Marian Mârza, Raluca Marica, Mădălina Florina Dragomir, Alina Oana Rusu-Moldovan, Mărioara Moldovan, Paula Maria Pașca and Liviu Oana
Life 2024, 14(9), 1097; https://doi.org/10.3390/life14091097 - 30 Aug 2024
Viewed by 843
Abstract
Repairing or reconstructing significant bone defects is typically challenging. In the present study, two composite cements were used as scaffolds in a sub-critical femoral defect in rats. A control group and two experimental batches were used to compare the outcomes. This research aimed [...] Read more.
Repairing or reconstructing significant bone defects is typically challenging. In the present study, two composite cements were used as scaffolds in a sub-critical femoral defect in rats. A control group and two experimental batches were used to compare the outcomes. This research aimed to investigate the osteogenic potential and toxicological tolerance of the bioproducts through histopathology and computed tomography imaging analysis at 14, 28, 56, and 90 days post-implantation. The biomaterials used in the investigation consisted of a 65% bioactive salinized inorganic filler and a 25% weight organic matrix. The organic part of the biomaterial was composed of Bis-GMA (bisphenol A-glycidyl methacrylate), UDMA (urethane dimethacrylate), HEMA (2-Hydroxyethyl methacrylate), and TEGDMA (triethylene glycol dimethacrylate), while the inorganic filler was composed of silica, barium glass, hydroxyapatite, and fluor aluminosilicate glass. The first findings of this research are encouraging, revealing that there is a slight difference between the groups treated with biomaterials, but it might be an effective approach for managing bone abnormalities. Material C1 exhibited a faster bone defect healing time compared to material C2, where bone fractures occurred in some individuals. It is unclear if the fractures were caused by the presence of the biomaterial C2 or whether additional variables were to blame. By the end of the research, the mice appeared to tolerate the biomaterials without exhibiting any inflammatory or rejection responses. Full article
(This article belongs to the Special Issue Veterinary Pathology and Veterinary Anatomy: 2nd Edition)
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11 pages, 8469 KiB  
Article
Exploring Lacrimal Gland Tear Production in Sheep under General Anesthesia: Examining the Potential Impact of Utilizing 1% Hyaluronic Acid Ophthalmic Gel
by Ruxandra Pavel, Ioana Ene and Ruxandra Costea
Life 2024, 14(8), 1038; https://doi.org/10.3390/life14081038 - 20 Aug 2024
Cited by 2 | Viewed by 775
Abstract
The aim of the study is to assess the lacrimal gland tear production, using the Schirmer Tear Test (STT), in healthy sheep under general anesthesia and to explore the effects of applying 1% hyaluronic acid ophthalmic gel during general anesthesia. While STT values [...] Read more.
The aim of the study is to assess the lacrimal gland tear production, using the Schirmer Tear Test (STT), in healthy sheep under general anesthesia and to explore the effects of applying 1% hyaluronic acid ophthalmic gel during general anesthesia. While STT values during anesthesia have been well documented in small animals such as cats and dogs, there seems to be a lack of information available for ruminants like sheep. This gap in the literature highlights the need for further research and exploration into tear production in sheep under anesthesia. The experimental research conducted on twelve adults female sheep provided valuable insights into tear production under anesthesia. By assessing tear production at various key time points the study was able to capture the changes in tear production throughout anesthesia and revealed a significant decrease in Schirmer Tear Test values in all sheep, following general anesthesia. The results showed that closing and taping the eye yielded determined better outcomes compared to administering a 1% lubricant ophthalmic gel. This finding suggests that eye care during anesthesia can impact tear production in sheep. Full article
(This article belongs to the Special Issue Veterinary Pathology and Veterinary Anatomy: 2nd Edition)
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11 pages, 10214 KiB  
Case Report
Electroencephalographic Features of Presumed Hepatic Encephalopathy in a Pediatric Dog with a Portosystemic Shunt—A Case Report
by Raluca Adriana Ștefănescu, Vasile Boghian, Gheorghe Solcan, Mario Darius Codreanu and Mihai Musteata
Life 2025, 15(1), 107; https://doi.org/10.3390/life15010107 - 16 Jan 2025
Viewed by 465
Abstract
Hepatic encephalopathy (HE) in dogs is a metabolic disorder of the central nervous system that occurs secondarily to liver dysfunctions, whether due to acquired or congenital causes. A portosystemic shunt is the presence of abnormal communications between the hepatic vessels (portal and suprahepatic [...] Read more.
Hepatic encephalopathy (HE) in dogs is a metabolic disorder of the central nervous system that occurs secondarily to liver dysfunctions, whether due to acquired or congenital causes. A portosystemic shunt is the presence of abnormal communications between the hepatic vessels (portal and suprahepatic veins). As a result of this, the blood brought from the digestive tract through the portal vein bypasses the liver, and the unmetabolized components of the portal bloodstream enter directly into systemic circulation, causing clinical symptoms of metabolic encephalopathy (HE). A 3-month-old Bichon canine patient with a history of seizures secondarily to a portosystemic shunt (PS), confirmed through color Doppler ultrasound exam and computed tomography, was presented for evaluation. The typical electroencephalographic (EEG) traces recorded were characterized by the presence of bilateral symmetrical triphasic waves, resembling non-convulsive status epilepticus. The presence of this EEG pattern is useful in choosing the best therapeutic option in order to not accentuate the HE sings and, consequently, to decrease the mortality risk due to a prolonged status epilepticus. Full article
(This article belongs to the Special Issue Veterinary Pathology and Veterinary Anatomy: 2nd Edition)
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7 pages, 5576 KiB  
Case Report
Chronic Copper Bilysinate Poisoning in Five Texel Sheep: A Case Report
by Dalma Pivariu, Adrian Nechita Oros, Alexandru Tabaran, Francesca Caloni, Pompei Bolfa and Andras-Laszlo Nagy
Life 2024, 14(11), 1363; https://doi.org/10.3390/life14111363 - 24 Oct 2024
Viewed by 824
Abstract
Copper is an essential trace element but becomes toxic in overexposed animals. Sheep are the domestic species most prone to chronic copper poisoning, as a slight increase in the dietary concentration can lead to liver accumulation and the development of clinical signs in [...] Read more.
Copper is an essential trace element but becomes toxic in overexposed animals. Sheep are the domestic species most prone to chronic copper poisoning, as a slight increase in the dietary concentration can lead to liver accumulation and the development of clinical signs in this species. Common sources of copper in the diet are feed additives and mineral supplements, which are commonly used in pigs and poultry. Recently, new copper supplements were registered for animal nutrition, including copper bilysinate. This study describes an episode of presumed chronic copper poisoning in Five Texel sheep, which were exposed to a compound feed containing copper bilysinate. Four weeks after the introduction of the compound feed into the diet, the first animal started to show typical clinical signs of chronic copper poisoning and died, followed by another animal a week later. Despite removing the compound feed from the diet, a third sheep died 3 weeks later. Two animals survived and fully recovered. Necropsy and histology showed characteristic gross and microscopical lesions typical of copper poisoning. The case report highlights the potential toxic effect of copper bilysinate in sheep. Full article
(This article belongs to the Special Issue Veterinary Pathology and Veterinary Anatomy: 2nd Edition)
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10 pages, 4587 KiB  
Case Report
Non-Invasive Paraclinical Diagnosis of Hepatocutaneous Syndrome in a Dog
by Anamaria-Hortensia Strichea, Ștefania Livia Hreniuc and Gheorghe Solcan
Life 2024, 14(7), 853; https://doi.org/10.3390/life14070853 - 8 Jul 2024
Viewed by 2217
Abstract
A 14-year-old, female spayed Bichon Maltese with no other known previous pathologies was presented for dermatological examination after being referred from a private clinic with the suspicion of generalized, treatment-resistant demodicosis. Upon presentation and clinical examination, multiple deep skin scrapings were performed, returning [...] Read more.
A 14-year-old, female spayed Bichon Maltese with no other known previous pathologies was presented for dermatological examination after being referred from a private clinic with the suspicion of generalized, treatment-resistant demodicosis. Upon presentation and clinical examination, multiple deep skin scrapings were performed, returning negative parasitological results. Complete blood count and serum biochemistry revealed mild hepatic damage. Abdominal ultrasound revealed an abnormal echostructure of the liver displaying a honeycomb or Swiss cheese-like pattern, reported as pathognomonic for hepatocutaneous syndrome. The owner declined any further paraclinical examination, including skin biopsy and histopathological examination, requesting a treatment protocol that could be pursued at home, considering the age of the dog and its reactive behavior during the examination. The present case report highlights a non-invasive method of diagnosing the hepatocutaneous syndrome in a dog by clinical examination, routine blood testing, and ultrasound assessment of the abdomen, in the absence of the possibility of doing a histopathological diagnosis. Full article
(This article belongs to the Special Issue Veterinary Pathology and Veterinary Anatomy: 2nd Edition)
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