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Life
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Advances in Thoracic Medicine and Thoracic Surgery
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Advances in Thoracic Medicine and Thoracic Surgery

A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Medical Research".

Deadline for manuscript submissions: closed (29 February 2024) | Viewed by 2254

Special Issue Editors

Dr. Shih-Chun Lee

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Guest Editor
Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan
Interests: lung cancer; esophageal cancer; mediastinal tumor; thoracic surgery
Dr. Yuan-Ming Tsai

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Guest Editor
Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan
Interests: lung cancer; esophageal cancer; thoracic surgery; robotic surgery; VATS; medical education; calcium imaging

Special Issue Information

Dear Colleagues,

Lung cancer surgery is currently experiencing a significant transformation on multiple fronts. First, there has been remarkable progress in minimally invasive surgery, exemplified by advancements like robot-assisted thoracic surgery (RATS) and uniportal-video-assisted thoracic surgery (UVATS). Second, recent advancements in interventional bronchoscopy have been made to screen, diagnose, and treat pulmonary lesions. However, these new techniques require further studies to establish their utility in clinical practice. Third, perioperative treatments involving molecularly targeted drugs and immune checkpoint inhibitors have begun to be integrated into the management of patients with resectable locally advanced lung cancer. Yet, there are still many unresolved issues to contend with, such as selecting the right patients for these treatments and determining the optimal timing of treatment administration. This Special Issue seeks to delve into these diverse issues and advancements, offering valuable insights into the field of lung cancer surgery.

Dr. Shih-Chun Lee
Dr. Yuan-Ming Tsai
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Life is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • lung cancer
  • video-associated thoracic surgery
  • robotic
  • uniportal
  • interventional pulmonology
  • navigational bronchoscopy
  • immune checkpoint inhibitor
  • molecular-targeted drug

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Published Papers (1 paper)

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Research

13 pages, 1345 KiB  
Article
Comparison of Early Postoperative Diaphragm Muscle Function after Lobectomy via VATS and Open Thoracotomy: A Sonographic Study
by Janusz Kocjan, Mateusz Rydel, Damian Czyżewski and Mariusz Adamek
Life 2024, 14(4), 487; https://doi.org/10.3390/life14040487 - 9 Apr 2024
Viewed by 1006
Abstract
Although a growing body of evidence emphasizes the superiority of VATS over conventional thoracotomy, little is still known about early postoperative diaphragm muscle function after lobectomy via these two approaches. To fill the gap in existing literature, we conducted a comparative study between [...] Read more.
Although a growing body of evidence emphasizes the superiority of VATS over conventional thoracotomy, little is still known about early postoperative diaphragm muscle function after lobectomy via these two approaches. To fill the gap in existing literature, we conducted a comparative study between VATS and conventional thoracotomy in terms of postoperative diaphragm muscle function, assessing its contractility, strength, the magnitude of effort and potential risk of dysfunction such as atrophy and paralysis. A total of 59 patients (30 after VATS), who underwent anatomical pulmonary resection at our institution, were enrolled in this study. The control group consisted of 28 health subjects without medical conditions that could contribute to diaphragm dysfunction. Diaphragm muscle was assessed before and after surgery using ultrasonography. We found that both surgical approaches were associated with postoperative impairment of diaphragm muscle function—compared to baseline data. Postoperative reduction in diaphragm contraction was demonstrated in most of the 59 patients. In the case of the control group, the differences between measurements were not observed. We noted that lobectomy via thoracotomy was linked with a greater percentage of patients with diaphragm paralysis and/or atrophy than VATS. Similar findings were observed in referring to diaphragm magnitude effort, as well as diaphragm contraction strength, where minimally invasive surgery was associated with better diaphragm function parameters—in comparison to thoracotomy. Disturbance of diaphragm work was reported both at the operated and non-operated side. Upper-right and left lobectomy were connected with greater diaphragm function impairment than other segments. In conclusion, the VATS technique seems to be less invasive than conventional thoracotomy providing a better postoperative function of the main respiratory muscle. Full article
(This article belongs to the Special Issue Advances in Thoracic Medicine and Thoracic Surgery)
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