New Insights into Allergic Eye Diseases
A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Medical Research".
Deadline for manuscript submissions: 30 June 2025 | Viewed by 7378
Special Issue Editors
Interests: ocular immunology; ocular microbiology; ocular disease
Interests: ophthalmology; ocular ultrasound; medical retina; retinal diseases; glaucoma
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The ocular surface is constantly exposed to environmental allergens. Allergic eye diseases are common ophthalmic disorders that affect millions globally. The forms of ocular disorders range in severity from mild to sight-threatening. The usual clinical manifestations of allergic eye diseases include itching, eyelid edema, conjunctival hyperemia, chemosis, conjunctival fibroproliferative lesions, and keratitis. Allergic eye disease is an inflammation of the ocular surface mediated by IgE-dependent and/or IgE-independent immunopathogenic mechanisms. Seasonal and perennial variants of allergic conjunctivitis are IgE-dependent hypersensitivity immune reactions. Vermal keratoconjunctivitis and atopic keratoconjunctivitis involve IgE-dependent and IgE-independent immunopathological mechanisms. The pathology of giant papillary conjunctivitis involves immune and non-immune mechanisms.
Immune and pathological mechanisms play a vital role in allergic eye diseases; however, our understanding of the molecular and cellular aspects of immune and pathological mechanisms is not fully elucidated. Nevertheless, innovations in the area of immune and pathological mechanisms of allergic eye diseases will provide breakthroughs in potential therapeutic targets in allergic eye diseases. Targeted therapy that controls and suppresses allergic reactions have become readily available; however, there is ongoing research focused on developing innovative therapy aimed at inhibiting immune cells, mediators, and cellular receptors that facilitate the immunopathogenesis and immunopathology of allergic eye diseases. There is also ongoing research that is focused on developing enhanced delivery methods of anti-allergic therapeutics.
The purpose of this Special Issue is to highlight current research on the cellular and molecular aspects of immune and pathological mechanisms of allergic eye diseases. This Special Issue will also highlight breakthroughs in potential therapeutic targets that will go a long way towards developing targeted therapies with enhanced benefits. You are encouraged to submit original research or review articles for consideration to broaden our current understanding of immunopathogenesis, immunopathology, and management of allergic eye diseases.
Prof. Dr. De Gaulle I. Chigbu
Dr. Livio Vitiello
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Life is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- allergy
- IgE
- IL-4
- IL-5
- IL-13
- TNF-alpha
- mast cells
- eosinophils
- Th1 cells
- Th2 cells
- therapeutics
- immunopathogenesis
- immunopathology
- conjunctivitis
- keratoconjunctivitis
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