New Diagnostic and Therapeutic Developments in Eye and Systemic Diseases

A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Medical Research".

Deadline for manuscript submissions: 30 April 2025 | Viewed by 958

Special Issue Editor


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Guest Editor
Doheny Image Analysis Laboratory, Doheny Eye Institute, Pasadena, CA 91103, USA
Interests: artificial intelligence (AI); machine learning; deep learning; computer vision in the fields of automated screening and classification; novel biomarkers’ discovery; quantitative prediction of progressive growth; image segmentation and registration on 2D and 3D images with various eye diseases

Special Issue Information

Dear Colleagues,

Ophthalmology has been at the forefront of medical innovation due to its unique demand for device-assisted diagnostics and microsurgery. Recent technological developments have radically impacted the daily practices of ophthalmologists thanks to the advent of novel diagnostic and therapeutic tools that facilitate the early diagnosis of eye diseases and systemic diseases (i.e., oculomics), allowing for the better management of not only ocular disorders but also systemic disorders affecting the entire body. The use of modern devices not only permits the earlier detection of eye diseases and systemic diseases but also allows ophthalmologists to offer more individualized treatment to their patients. For this Special Issue, we request research including new findings in the fields of diagnostic and therapeutic developments in eye diseases and systemic diseases. Our goal is to discuss, amongst others, diagnostic imaging, molecular pathology diagnosis (biomarkers), artificial intelligence diagnosis, and innovative treatment options in the field of ophthalmology.

Primarily, we welcome submissions of high-quality original research articles showcasing new developments and innovative findings on these topics. Secondarily, we will consider high-interest review articles and case series of exceptional quality.

Dr. Zhihong Jewel Hu
Guest Editor

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Keywords

  • eye diseases
  • systemic diseases
  • oculomics
  • ocular imaging
  • eye surgery
  • retina
  • cornea
  • glaucoma
  • refractive surgery
  • OCT
  • OCTA

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Published Papers (1 paper)

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Research

11 pages, 2104 KiB  
Article
Short-Term Visual and Refractive Outcomes of Single-Step Transepithelial Photorefractive Keratectomy with Amaris 750S and SmartSurfACE in Myopia and Astigmatism: A 6-Month Follow-Up Study
by Daiana-Andreea Margarit, Horia Tudor Stanca, Valeria Mocanu, Mihnea Munteanu, Suta Marius and Suta Gheorghita
Life 2024, 14(10), 1288; https://doi.org/10.3390/life14101288 - 11 Oct 2024
Viewed by 762
Abstract
Background: Single-step transepithelial photorefractive keratectomy (TPRK) is a modern refractive surgery technique that offers a no-touch approach for correcting myopia and astigmatism. This study aims to evaluate the short-term visual and refractive outcomes of TPRK in patients with myopia and astigmatism over a [...] Read more.
Background: Single-step transepithelial photorefractive keratectomy (TPRK) is a modern refractive surgery technique that offers a no-touch approach for correcting myopia and astigmatism. This study aims to evaluate the short-term visual and refractive outcomes of TPRK in patients with myopia and astigmatism over a 6-month follow-up period. Methods: This retrospective cohort study included patients who underwent single-step TPRK using the Amaris 750S laser platform with SmartSurfACE and SmartPulse® technologies, targeting a plano refraction. Procedures were performed with aspheric, non-wavefront-guided profiles, and outcomes were assessed postoperatively. Results: 96% of eyes achieved 20/20 or better uncorrected distance visual acuity (UDVA), with 98% reaching 20/25 or better, and 100% achieving 20/32 or better. UDVA was the same or better than preoperative corrected distance visual acuity (CDVA) in 96% of eyes, and no eyes lost two or more Snellen lines. Refractive outcomes showed strong precision, with 93% of eyes within ±1.00 D of the target. Astigmatism correction was accurate, with 100% of eyes having ≤1.00 D of astigmatism, and 80% achieving a precise astigmatism angle of error between −5° and 5°. Conclusion: Single-step TPRK with SmartSurfACE and SmartPulse® technologies provides highly effective and predictable visual and refractive outcomes for myopia and astigmatism. The procedure consistently delivers precise corrections with minimal complications, making it a reliable option for refractive surgery. Full article
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