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Life
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Recent Advances in Shockwave Therapy for Musculoskeletal and Soft-Tissue Disorders
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Recent Advances in Shockwave Therapy for Musculoskeletal and Soft-Tissue Disorders

A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Medical Research".

Deadline for manuscript submissions: 31 December 2024 | Viewed by 2145

Special Issue Editors

Prof. Dr. Marco Gesi

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Guest Editor
1. Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, 56126 Pisa, Italy
2. Center for Rehabilitative Medicine “Sport and Anatomy”, University of Pisa, 56126 Pisa, Italy
Interests: rehabilitation and sports physiotherapy; virtual reality; mixed/augmented reality; shock wave therapy; shockwave treatment
Special Issues, Collections and Topics in MDPI journals
Prof. Dr. Mario Vetrano

E-Mail Website1 Website2
Guest Editor
1. Department of Medical-Surgical and Translational Medicine Sciences, Sapienza University of Rome, 00189 Rome, Italy
2. Physical Medicine and Rehabilitation Unit, Sant’Andrea Hospital, Sapienza University of Rome, 00189 Rome, Italy
Interests: orthopaedic sports medicine
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Prof. Dr. Maria Chiara Vulpiani

E-Mail Website
Guest Editor
Department of Medical-Surgical and Translational Medicine Sciences, La Sapienza University of Rome, 00185 Rome, Italy
Interests: orthopaedic sports medicine; shockwaves therapy; tendon pathology; musculoskeletal pathologies
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Dr. Maria Cristina D'Agostino

E-Mail Website
Guest Editor
Shock Waves Center, Ortho-Rehabilitation Department, IRCCS Humanitas Research Hospital and Humanitas University, 20048 Rozzano, Italy
Interests: shockwaves therapy; regenerative medicine; orthopedic sports medicine; tendon patology; musculo-skeletal patologies; rehabilitation; orthopedic medicine
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Dr. Larisa Ryskalin

E-Mail Website
Guest Editor
1. Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, 56126 Pisa, Italy
2. Center for Rehabilitative Medicine “Sport and Anatomy”, University of Pisa, 56126 Pisa, Italy
Interests: transmission electron microscopy; fascia; cell signaling; anatomy; autophagy; immunocytochemistry; cellular biology
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Dr. Federica Fulceri

E-Mail Website
Guest Editor
1. Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, 56126 Pisa, Italy
2. Center for Rehabilitative Medicine “Sport and Anatomy”, University of Pisa, 56126 Pisa, Italy
Interests: human anatomy; transmission electron microscopy; immunocitochemistry; physical therapy and rehabilitation; murine motor and behavioural tests
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

This Special Issue, which is titled "Recent Advances in Shockwave Therapy for Musculoskeletal and Soft-Tissue Disorders", presents a comprehensive overview of research highlighting the latest breakthroughs in the application of shockwave therapy for the treatment of a variety of physical problems and pathological conditions involving the musculoskeletal system.

Being first introduced into routine clinical practice in the 1980s for treating urinary stones (lithotripsy), the application of extracorporeal shock wave therapy (ESWT) has rapidly expanded across a wide range of medical specialties, yielding  promising outcomes for bones and soft-tissue healing, pain relief, and functional recovery. Due to the negligible side effects, such as pain during ESWT sessions and minor hematoma, this therapy represents a safe, advantageous, and well-tolerated approach without surgical risks or severe complications. Therefore, ESWT has gained increasing popularity for treating different musculoskeletal disorders and soft-tissue injuries.

Although increasing evidence indicates that the application of ESWT to the locomotor system may lead to various benefits beyond a mere mechanical disintegrative effect, the precise cellular and molecular mechanisms of shock waves are still largely unknown. At the same time, different forms of ESWT (i.e., radial and focal ESWT) and treatment protocols may have substantial influences on achieving therapeutic effects and thus good clinical outcomes. Therefore, further studies are needed to identify the optimal treatment protocol and appropriate setup parameters (i.e., dosage, interval of treatments, number of sessions) for target patient populations.

This Special Issue brings together review and original articles that delve into various aspects of ESWT to provide current evidence on novel treatment indications for shockwave therapy, the advantages/disadvantages of ESWT protocols, and controversies regarding ESWT, clinical indications, biological principles, and mechanisms of action.

You may choose our Joint Special Issue in Biomedicines.

Prof. Dr. Marco Gesi
Prof. Dr. Mario Vetrano
Prof. Dr. Maria Chiara Vulpiani
Dr. Maria Cristina D'Agostino
Dr. Larisa Ryskalin
Dr. Federica Fulceri
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Life is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • shockwave
  • tissue regeneration
  • pain
  • functional recovery and healing
  • physical medicine and rehabilitation
  • clinical applications
  • imaging

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Further information on MDPI's Special Issue polices can be found here.

Published Papers (2 papers)

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Research

15 pages, 923 KiB  
Article
Extracorporeal Shock Wave Therapy (ESWT) vs. Exercise in Thumb Osteoarthritis (SWEX-TO): Prospective Clinical Trial at 6 Months
by Ilaria Covelli, Silvana De Giorgi, Antonio Di Lorenzo, Angelo Pavone, Fabrizio Salvato, Francesco Rifino, Biagio Moretti, Giuseppe Solarino and Angela Notarnicola
Life 2024, 14(11), 1453; https://doi.org/10.3390/life14111453 - 8 Nov 2024
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Abstract
Rhizarthrosis is the most frequent form of osteoarthritis and is responsible for pain, disability and reduced functionality. The aim of the study is to investigate the clinical effects of shock wave treatment in patients suffering from arthritis of the first finger. A prospective [...] Read more.
Rhizarthrosis is the most frequent form of osteoarthritis and is responsible for pain, disability and reduced functionality. The aim of the study is to investigate the clinical effects of shock wave treatment in patients suffering from arthritis of the first finger. A prospective clinical study was designed, in which 72 patients affected by rhizarthrosis were randomized to treatment with shock waves or exercises; in both groups an immobilization brace was used on the first finger. At recruitment and at 1, 3 and 6 months, patients received assessments of pain (VAS), functionality (FIHOA) and disability (DASH); furthermore, the perception of improvement was monitored during follow-ups (Roles and Maudsley Score). In both groups there was a significant improvement in all scores in the comparison between recruitment and 6 months. The perception of improvement was statistically better in the shock wave group than in the exercise group at 1, 3 and 6 months. The regression analysis showed that the reduction of VAS and DASH were statistically influenced by shock wave treatment (p < 0.001). Both therapies are effective in managing patients suffering from arthritis of the first finger, but the shock wave treatment could ensure greater persistence of improvements. Full article
(This article belongs to the Special Issue Recent Advances in Shockwave Therapy for Musculoskeletal and Soft-Tissue Disorders)
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12 pages, 585 KiB  
Article
Predictive Prognostic Factors in Non-Calcific Supraspinatus Tendinopathy Treated with Focused Extracorporeal Shock Wave Therapy: An Artificial Neural Network Approach
by Gabriele Santilli, Mario Vetrano, Massimiliano Mangone, Francesco Agostini, Andrea Bernetti, Daniele Coraci, Marco Paoloni, Alessandro de Sire, Teresa Paolucci, Eleonora Latini, Flavia Santoboni, Sveva Maria Nusca and Maria Chiara Vulpiani
Life 2024, 14(6), 681; https://doi.org/10.3390/life14060681 - 25 May 2024
Cited by 2 | Viewed by 957
Abstract
The supraspinatus tendon is one of the most involved tendons in the development of shoulder pain. Extracorporeal shockwave therapy (ESWT) has been recognized as a valid and safe treatment. Sometimes the symptoms cannot be relieved, or a relapse develops, affecting the patient’s quality [...] Read more.
The supraspinatus tendon is one of the most involved tendons in the development of shoulder pain. Extracorporeal shockwave therapy (ESWT) has been recognized as a valid and safe treatment. Sometimes the symptoms cannot be relieved, or a relapse develops, affecting the patient’s quality of life. Therefore, a prediction protocol could be a powerful tool aiding our clinical decisions. An artificial neural network was run, in particular a multilayer perceptron model incorporating input information such as the VAS and Constant–Murley score, administered at T0 and at T1 after six months. It showed a model sensitivity of 80.7%, and the area under the ROC curve was 0.701, which demonstrates good discrimination. The aim of our study was to identify predictive factors for minimal clinically successful therapy (MCST), defined as a reduction of ≥40% in VAS score at T1 following ESWT for chronic non-calcific supraspinatus tendinopathy (SNCCT). From the male gender, we expect greater and more frequent clinical success. The more severe the patient’s initial condition, the greater the possibility that clinical success will decrease. The Constant and Murley score, Roles and Maudsley score, and VAS are not just evaluation tools to verify an improvement; they are also prognostic factors to be taken into consideration in the assessment of achieving clinical success. Due to the lower clinical improvement observed in older patients and those with worse clinical and functional scales, it would be preferable to also provide these patients with the possibility of combined treatments. The ANN predictive model is reasonable and accurate in studying the influence of prognostic factors and achieving clinical success in patients with chronic non-calcific tendinopathy of the supraspinatus treated with ESWT. Full article
(This article belongs to the Special Issue Recent Advances in Shockwave Therapy for Musculoskeletal and Soft-Tissue Disorders)
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