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Life
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Advances and Applications of Cardiac Surgery
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Advances and Applications of Cardiac Surgery

A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Medical Research".

Deadline for manuscript submissions: closed (31 August 2023) | Viewed by 4970

Special Issue Editors

Dr. Vladimir Shvartz

E-Mail Website
Guest Editor
Bakoulev Scientific Center for Cardiovascular Surgery, Department of Surgical Treatment for Interactive Pathology, Moscow, Russia
Interests: coronary heart disease; coronary artery bypass surgery; aortic valve disease; mitral valve disease; arrhythmias
Dr. Alexander M. Cherniavskiy

E-Mail Website
Guest Editor
E.N. Meshalkin National Medical Research Center, Novosibirsk, Russia
Interests: coronary heart disease; cardiac surgery; atrial fibrillation; heart failure
Dr. Soslan T. Enginoev

E-Mail Website
Guest Editor
1. Federal Center for Cardiovascular Surgery of the Russian Federation Ministry of Healthcare (Astrakhan), 414011 Astrakhan, Russia
2. Astrakhan State Medical University of the Russian Federation Ministry of Healthcare, 414000 Astrakhan, Russia
Interests: coronary artery bypass surgery; aortic valve replacement; mitral valve repair; procedure Ross; operations David and Bentall De Bono
Dr. Alim M. Namitokov

E-Mail Website
Guest Editor
1. Scientific Research Institute – Regional Clinical Hospital №1, Krasnodar, Russia
2. Therapeutic Department #1, Kuban State Medical University, Krasnodar, Russia
Interests: lipidology; acute coronary syndrome; aortic valve disease; heart failure

Special Issue Information

Dear Colleagues,

Nowadays, the development of advanced technologies in medicine leads to an increasing minimization of surgery, particularly cardiovascular surgery. Nevertheless, such classical operations as coronary artery bypass grafting, heart valve replacement, etc., remain relevant to this day. This Special Issue will contain a selection of articles covering current and controversial issues in the field of cardiovascular surgery.

This Special Issue, "Advances and Applications of Cardiac Surgery", is devoted to recent achievements in the field of cardiovascular surgery across a wide range of pathologies (congenital heart and vascular diseases, aortic, mitral and tricuspid valve diseases, coronary heart disease, cardiomyopathy, various cardiac arrhythmias and chronic heart failure). Issues related to the etiology, pathogenesis, clinic, diagnostics and surgical treatment of these diseases will be covered. Research devoted to cardiovascular surgery and comorbid pathologies and scientific research concerning heart transplantation are also welcome. Pathoanatomic research related to cardiac surgery can also be covered in this Special Issue.

We welcome the submission of original research (fundamental and clinical), clinical cases and review manuscripts.

Dr. Vladimir Shvartz
Dr. Alexander M. Cherniavskiy
Dr. Soslan T. Enginoev
Dr. Alim M. Namitokov
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Life is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • congenital heart diseases
  • surgical treatment
  • coronary artery bypass surgery
  • coronary heart disease
  • aortic valve disease
  • mitral valve disease
  • arrhythmias
  • hybrid approach
  • cardiomyopathy
  • radiofrequency ablation

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Further information on MDPI's Special Issue polices can be found here.

Published Papers (3 papers)

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Research

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13 pages, 634 KiB  
Article
The Role of «Novel» Biomarkers of Systemic Inflammation in the Development of Early Hospital Events after Aortic Valve Replacement in Patients with Aortic Stenosis
by Vladimir Shvartz, Maria Sokolskaya, Artak Ispiryan, Madina Basieva, Polina Kazanova, Elena Shvartz, Sayali Talibova, Andrey Petrosyan, Teymuraz Kanametov, Sergey Donakanyan, Leo Bockeria and Elena Golukhova
Life 2023, 13(6), 1395; https://doi.org/10.3390/life13061395 - 14 Jun 2023
Cited by 4 | Viewed by 1921
Abstract
Introduction. The pathogenesis of aortic stenosis includes the processes of chronic inflammation, calcification, lipid metabolism disorders, and congenital structural changes. The goal of our study was to determine the predictive value of novel biomarkers of systemic inflammation and some hematological indices based on [...] Read more.
Introduction. The pathogenesis of aortic stenosis includes the processes of chronic inflammation, calcification, lipid metabolism disorders, and congenital structural changes. The goal of our study was to determine the predictive value of novel biomarkers of systemic inflammation and some hematological indices based on the numbers of leukocytes and their subtypes in the development of early hospital medical conditions after mechanical aortic valve replacement in patients with aortic stenosis. Materials and methods. This was a cohort study involving 363 patients who underwent surgical intervention for aortic valve pathology between 2014 and 2020. The following markers of systemic inflammation and hematological indices were studied: SIRI (Systemic Inflammation Response Index), SII (Systemic Inflammation Index), AISI (Aggregate Index of Systemic Inflammation), NLR (Neutrophil/Lymphocyte Ratio), PLR (Platelet/Lymphocyte Ratio), and MLR (Monocyte/Lymphocyte Ratio). Associations of the levels of these biomarkers and indices with the development of in-hospital death, acute kidney injury, postoperative atrial fibrillation, stroke/acute cerebrovascular accident, and bleeding were calculated. Results. According to an ROC analysis, an SIRI > 1.5 (p < 0.001), an SII > 718 (p = 0.002), an AISI > 593 (p < 0.001), an NLR > 2.48 (p < 0.001), a PLR > 132 (p = 0.004), and an MLR > 0.332 (p < 0.001) were statistically significantly associated with in-hospital death. Additionally, an SIRI > 1.5 (p < 0.001), an NLR > 2.8 (p < 0.001), and an MLR > 0.392 (p < 0.001) were associated with bleeding in the postoperative period. In a univariate logistic regression, SIRI, SII, AISI, and NLR were statistically significant independent factors associated with in-hospital death. In a multivariate logistic regression model, SIRI was the most powerful marker of systemic inflammation. Conclusion. SIRI, SII, AISI, and NLR as novel biomarkers of systemic inflammation were associated with in-hospital mortality. Of all markers and indices of systemic inflammation in our study, SIRI was the strongest predictor of a poor outcome in the multivariate regression model. Full article
(This article belongs to the Special Issue Advances and Applications of Cardiac Surgery)
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Review

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23 pages, 2006 KiB  
Review
A Literature Review on the Use of Aortic Allografts in Modern Cardiac Surgery for the Treatment of Infective Endocarditis: Is There Clear Evidence or Is It Merely a Perception?
by Francesco Nappi, Thibaut Schoell, Cristiano Spadaccio, Christophe Acar and Francisco Diniz Affonso da Costa
Life 2023, 13(10), 1980; https://doi.org/10.3390/life13101980 - 28 Sep 2023
Cited by 2 | Viewed by 1214
Abstract
Infective valve endocarditis is caused by different pathogens and 60% of those involve the aortic valve with valve failure. Although S. aureus is recognized as the most frequently isolated causative bacterium associated with IE in high-income countries, Gram-positive cocci nevertheless play a crucial [...] Read more.
Infective valve endocarditis is caused by different pathogens and 60% of those involve the aortic valve with valve failure. Although S. aureus is recognized as the most frequently isolated causative bacterium associated with IE in high-income countries, Gram-positive cocci nevertheless play a crucial role in promoting infection in relation to their adhesive matrix molecules. The presence of pili on the surface of Gram-positive bacteria such as in different strains of Enterococcus faecalis and Streptococcus spp., grants these causative pathogens a great offensive capacity due to the formation of biofilms and resistance to antibiotics. The indications and timing of surgery in endocarditis are debated as well as the choice of the ideal valve substitute to replace the diseased valve(s) when repair is not possible. We reviewed the literature and elaborated a systematic approach to endocarditis management based on clinical, microbiological, and anatomopathological variables known to affect postoperative outcomes with the aim to stratify the patients and orient decision making. From this review emerges significant findings on the risk of infection in the allograft used in patients with endocarditis and no endocarditis etiology suggesting that the use of allografts has proved safety and effectiveness in patients with both pathologies. Full article
(This article belongs to the Special Issue Advances and Applications of Cardiac Surgery)
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Other

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13 pages, 1573 KiB  
Case Report
Transapical Approach to Septal Myectomy for Hypertrophic Cardiomyopathy
by Alexander Afanasyev, Alexander Bogachev-Prokophiev, Sergei Zheleznev, Mikhail Ovcharov, Anton Zalesov, Ravil Sharifulin, Igor’ Demin, Bashir Tsaroev, Vladimir Nazarov and Alexander Chernyavskiy
Life 2024, 14(1), 125; https://doi.org/10.3390/life14010125 - 15 Jan 2024
Cited by 1 | Viewed by 1203
Abstract
A 63-year-old symptomatic female with apical hypertrophic cardiomyopathy and diastolic disfunction was admitted to the hospital. What is the best way to manage this patient? This study is a literature review that was performed to answer this question. The following PubMed search strategy [...] Read more.
A 63-year-old symptomatic female with apical hypertrophic cardiomyopathy and diastolic disfunction was admitted to the hospital. What is the best way to manage this patient? This study is a literature review that was performed to answer this question. The following PubMed search strategy was used: ‘Hypertrophic obstructive cardiomyopathy’ [All Fields] OR ‘apical myectomy’ [All Fields], NOT ‘animal [mh]’ NOT ‘human [mh]’ NOT ‘comment [All Fields]’ OR ‘editorial [All Fields]’ OR ‘meta-analysis [All Fields]’ OR ‘practice-guideline [All Fields]’ OR ‘review [All Fields]’ OR ‘pediatrics [mh]’. The natural history of the disease has a benign prognosis; however, a watchful strategy was associated with the risk of adverse cardiovacular events. Contrastingly, transapical myectomy was associated with low surgical risk and acceptable outcomes. In our case, the patient underwent transapical myectomy with an unconventional post-operative period. Control echocardiography showed marked left ventricular (LV) cavity enlargement: LV end-diastolic volume, 74 mL; LV ejection fraction, 65%; and LV stroke volume index increased to 27 mL/m2. The patient was discharged 7 days after myectomy. At 6 months post-operation, the patient was NYHA Class I, with a 6 min walk test score of 420 m. Therefore, transapical myectomy may be considered as a feasible procedure in patients with apical hypertrophic cardiomyopathy and progressive heart failure. Full article
(This article belongs to the Special Issue Advances and Applications of Cardiac Surgery)
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