Oxidative Stress and Antioxidants: Impact on Reproduction
A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Reproductive and Developmental Biology".
Deadline for manuscript submissions: closed (11 November 2021) | Viewed by 3600
Special Issue Editors
Interests: oxidative stress; animal reproduction; nutraceuticals; phytotherapy; animal welfare
Special Issues, Collections and Topics in MDPI journals
Interests: veterinary phisiology; animal welfare; oxidative stress; human-animal relationship; reproductive behavior
Special Issue Information
Dear Colleagues,
The role of oxidative stress in reproductive systems is still matter of scientific debate. Oxidative stress is a state characterized by an impaired modulation of free radicals that cause many events related to infertility both in humans and animals. Meanwhile, the presence of oxidant species is a prerequisite for various metabolic and physiological functions (e.g., mitochondrial respiration, oxidase catalyzed reactions), as long as low free radical concentrations are maintained. Mammals have evolved antioxidant defense systems, composed either by endogenous or exogenous compounds, which play a role in preventing free radical generation, inactivating oxidants and limiting the deleterious effects of oxidants by allowing repair of oxidative damage. It seems that a deficiency in any part of the antioxidant defense system can cause a decrease in total antioxidant capability. The manipulation of the antioxidant mechanisms has been proposed as strategy to reduce oxidative stress and thereby to improve in vivo or in vitro fertilization success rates.
This Special Issue of Life aims to collect the most significant and recent research regarding the effect of oxidative stress in reproduction and the use of antioxidants (e.g., diet, extender, medium, gamete and blastocyst cooling, gamete and blastocyst cryopreservation) to achieve fertilization and pregnancy. Authors are invited to submit relevant research studies, review articles, and case reports about the physiological roles of free radicals, as well as their negative effects on the reproductive processes and about the different strategies adopted to counteract free radicals by specific antioxidants.
Dr. Francesca Ciani
Dr. Danila d’Angelo
Dr. Chiara Del Prete
Guest Editors
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