Imaging in Retinal Diseases

A special issue of Medicina (ISSN 1648-9144).

Deadline for manuscript submissions: closed (31 December 2020) | Viewed by 3276

Special Issue Editor

Ophthalmology Clinic, Department of Medicine and Science of Ageing, University G. D’Annunzio Chieti-Pescara, Chieti, Via dei Vestini 31, 66100 Chieti, Italy
Interests: optical coherence tomography; optical coherence tomography angiography; retinal diseases; retinal imaging; cataract surgery
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Special Issue Information

Dear Colleagues,

Retinal imaging has evolved considerably in the most recent years, enabling a better understanding of retinal anatomy in physiological conditions, the identification of retinal changes in the early stages of the diseases, and the signs of disease progression, as well as the recognition of imaging biomarkers of retinal response after pharmacological and surgical treatments.

Optical coherence tomography (OCT), OCT angiography, and widefield retinal imaging are innovative imaging techniques in the armamentarium of retinal specialists that have broadened their understanding of retinal pathology and enhanced patient care.

This Special Issue explores the latest developments in the field of imaging of retinal diseases and its clinical applications.

Dr. Lisa Toto
Guest Editor

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Keywords

  • optical coherence tomography
  • optical coherence tomography angiography
  • retinal diseases
  • retinal imaging
  • pharmacological treatment of retinal diseases
  • surgical treatment of retinal disease

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Published Papers (1 paper)

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Research

9 pages, 1659 KiB  
Article
Functional and Structural Reliability of Optic Nerve Head Measurements in Healthy Eyes by Means of Optical Coherence Tomography Angiography
by Rodolfo Mastropasqua, Rossella D’Aloisio, Luca Agnifili, Eduardo Zuppardi, Guido Di Marzio, Marta Di Nicola, Annamaria Porreca, Daniele Guarini, Michele Totta, Lorenza Brescia and Luca Di Antonio
Medicina 2020, 56(1), 44; https://doi.org/10.3390/medicina56010044 - 20 Jan 2020
Cited by 6 | Viewed by 2716
Abstract
Background and Objectives: the aim of the study was to evaluate the repeatability and reproducibility of optical microangiography (OMAG)-based optical coherence tomography angiography (OCTA) in the optic nerve head (ONH) and radial peripapillary capillary (RPC) perfusion assessment of healthy eyes. Materials and [...] Read more.
Background and Objectives: the aim of the study was to evaluate the repeatability and reproducibility of optical microangiography (OMAG)-based optical coherence tomography angiography (OCTA) in the optic nerve head (ONH) and radial peripapillary capillary (RPC) perfusion assessment of healthy eyes. Materials and Methods: in this observational study, a total of 40 healthy subjects underwent ONH evaluation, using an OMAG-based OCTA system at baseline (T0), after 30 min (T1), and after 7 days (T2). The main outcome measures were the vessel density (VD) and flux index (FI) of the RPCs, as well as peri-papillary retinal nerve fibre layer (pRNFL) thickness. The analysis was performed by two observers independently. The coefficient of repeatability (CR), within the subject coefficient of variation (CVw) and intrasession correlation coefficient (ICC), to evaluate intrasession repeatability of measurements was calculated for each observer. Results: the high intrasession and intersession repeatability and reproducibility were assessed in the two observers for all three outcome measures. Of note, the CRs for the first and the second observer were 0.011 (95% confidence interval (CI) 0.009–0.014) and 0.016 (95% CI 0.013–0.020) for FI, 0.016 (95% CI 0.013–0.021) and 0.017 (95% CI 0.014–0.021) for VD, and 2.400 (95% CI 1.948–3.092) and 3.732 (95% CI 3.064–4.775) for pRNFL thickness, respectively. The agreement between them was excellent for pRNFL assessment and very good for FI and VD. Conclusion: OCTA has a great potential in the accurate assessment of ONH and peri-papillary microcirculation. It allows for repeated and reproducible measurements without multiple scans-related bias, thus guaranteeing an independent operator analysis with good reproducibility and repeatability. Full article
(This article belongs to the Special Issue Imaging in Retinal Diseases)
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