Metabolic Health and Weight

A special issue of Metabolites (ISSN 2218-1989). This special issue belongs to the section "Endocrinology and Clinical Metabolic Research".

Deadline for manuscript submissions: closed (30 November 2019) | Viewed by 13574

Special Issue Editor


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Guest Editor
1. Unidad de Gestión Clínica de Endocrinología y Nutrición del Hospital Virgen de la Victoria, Instituto de Investigación Biomédica de Málaga (IBIMA), Universidad de Málaga, 29010 Málaga, Spain
2. Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y la Nutrición, CIBERobn, 28029 Madrid, Spain
Interests: obesity; adipose tissue; gut microbiota; diet; bariatric surgery
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Special Issue Information

Dear Colleagues,

Obesity and its comorbidities are a worldwide problem. Weight variation implies a loss in homeostasis and the causes are diverse, not only an imbalance in what we eat and what we burn. Multiple aspects are implied, with a key role played by adipose tissue. Based on the complex network of the body’s metabolism, metabolites have become an essential part of exploring metabolic health and weight. This Special Issue of Metabolites, "Metabolic Health and Weight," will be dedicated to any aspect related to weight maintenance and homeostasis. The topics that will be covered by this Special Issue include, but are not limited to the identification of metabolites with biological and/or clinical relevance in obesity and its comorbidities, with a special interest in adipose tissue metabolites and metabolites derived from gut microbiota. Weight variations (weight gain and especially weight loss interventions) and their implications for the weight management and metabolic health are particularly of interest. Manuscripts dealing with other pertinent challenging issues are also highly desired.

Dr. Isabel Moreno-Indias
Guest Editor

Manuscript Submission Information

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Keywords

  • Adipose tissue
  • Gut microbiota
  • Obesity
  • Weight management

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Published Papers (2 papers)

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Review

26 pages, 815 KiB  
Review
Adipokines and Adipose Tissue-Related Metabolites, Nuts and Cardiovascular Disease
by Camila Weschenfelder, Alexandre Schaan de Quadros, Julia Lorenzon dos Santos, Silvia Bueno Garofallo and Aline Marcadenti
Metabolites 2020, 10(1), 32; https://doi.org/10.3390/metabo10010032 - 11 Jan 2020
Cited by 25 | Viewed by 5790
Abstract
Adipose tissue is a complex structure responsible for fat storage and releasing polypeptides (adipokines) and metabolites, with systemic actions including body weight balance, appetite regulation, glucose homeostasis, and blood pressure control. Signals sent from different tissues are generated and integrated in adipose tissue; [...] Read more.
Adipose tissue is a complex structure responsible for fat storage and releasing polypeptides (adipokines) and metabolites, with systemic actions including body weight balance, appetite regulation, glucose homeostasis, and blood pressure control. Signals sent from different tissues are generated and integrated in adipose tissue; thus, there is a close connection between this endocrine organ and different organs and systems such as the gut and the cardiovascular system. It is known that functional foods, especially different nuts, may be related to a net of molecular mechanisms contributing to cardiometabolic health. Despite being energy-dense foods, nut consumption has been associated with no weight gain, weight loss, and lower risk of becoming overweight or obese. Several studies have reported beneficial effects after nut consumption on glucose control, appetite suppression, metabolites related to adipose tissue and gut microbiota, and on adipokines due to their fatty acid profile, vegetable proteins, l-arginine, dietary fibers, vitamins, minerals, and phytosterols. The aim of this review is to briefly describe possible mechanisms implicated in weight homeostasis related to different nuts, as well as studies that have evaluated the effects of nut consumption on adipokines and metabolites related to adipose tissue and gut microbiota in animal models, healthy individuals, and primary and secondary cardiovascular prevention. Full article
(This article belongs to the Special Issue Metabolic Health and Weight)
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14 pages, 255 KiB  
Review
A New Perspective on the Health Benefits of Moderate Beer Consumption: Involvement of the Gut Microbiota
by Mar Quesada-Molina, Araceli Muñoz-Garach, Francisco J. Tinahones and Isabel Moreno-Indias
Metabolites 2019, 9(11), 272; https://doi.org/10.3390/metabo9110272 - 9 Nov 2019
Cited by 29 | Viewed by 7348
Abstract
Beer is the most widely consumed fermented beverage in the world. A moderate consumption of beer has been related to important healthy outcomes, although the mechanisms have not been fully understood. Beer contains only a few raw ingredients but transformations that occur during [...] Read more.
Beer is the most widely consumed fermented beverage in the world. A moderate consumption of beer has been related to important healthy outcomes, although the mechanisms have not been fully understood. Beer contains only a few raw ingredients but transformations that occur during the brewing process turn beer into a beverage that is enriched in micronutrients. Beer also contains an important number of phenolic compounds and it could be considered to be a source of dietary polyphenols. On the other hand, gut microbiota is now attracting special attention due to its metabolic effects and as because polyphenols are known to interact with gut microbiota. Among others, ferulic acid, xanthohumol, catechins, epicatechins, proanthocyanidins, quercetin, and rutin are some of the beer polyphenols that have been related to microbiota. However, scarce literature exists about the effects of moderate beer consumption on gut microbiota. In this review, we focus on the relationship between beer polyphenols and gut microbiota, with special emphasis on the health outcomes. Full article
(This article belongs to the Special Issue Metabolic Health and Weight)
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