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Metabolites
Special Issues
Epidemiology, Nutrition and Metabolism, 2nd Edition
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Epidemiology, Nutrition and Metabolism, 2nd Edition

A special issue of Metabolites (ISSN 2218-1989). This special issue belongs to the section "Nutrition and Metabolism".

Deadline for manuscript submissions: 25 January 2025 | Viewed by 1621

Special Issue Editors

Dr. Roberta Zupo

E-Mail Website
Guest Editor
Department of Interdisciplinary Medicine (DIM), University of Bari Aldo Moro, Piazza Giulio Cesare 11, 70100 Bari, Italy
Interests: nutrition; diet; public health; epidemiology; aging
Special Issues, Collections and Topics in MDPI journals
Dr. Maria Lisa Clodoveo

E-Mail Website
Guest Editor
Department of Interdisciplinary Medicine (DIM), University of Bari Aldo Moro, Piazza Giulio Cesare 11, 70100 Bari, Italy
Interests: food technologies; foods; olive oi; polyphenols; nutrition; diet
Special Issues, Collections and Topics in MDPI journals
Prof. Dr. Vincenzo Solfrizzi

E-Mail Website
Guest Editor
Department of Interdisciplinary Medicine (DIM), University of Bari Aldo Moro, Piazza Giulio Cesare 11, 70100 Bari, Italy
Interests: geriatrics; public health; epidemiology; aging
Special Issues, Collections and Topics in MDPI journals
Dr. Giuseppe Lisco

E-Mail Website
Guest Editor
Interdisciplinary Department of Medicine, School of Medicine, University of Bari “Aldo Moro”, Piazza Giulio Cesare 11, 70124 Bari, Italy
Interests: iodine; iodine prophylaxis; iodine, selenium and thyroid disorders; iodine deficiency related disorders; iodine deficiency and pregnancy
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Studies of diet in relation to human disease raise considerably more complicated methodological challenges than many epidemiological investigations. The specific contributions of nutritional epidemiology include dietary assessment, description of nutritional exposure, and statistical modeling of the diet–disease relationship. In all these areas, considerable progress has been made in recent years, some of which was explored in the previous Special Issue (Volume I). The goal of this special Research Topic is to shed light on the major advances achieved over the past decade in the field of nutritional epidemiology, with a focus on the role of diet in improving human health, and on future challenges to provide a comprehensive overview of the field and identify new avenues of research.

A deeper understanding of metabolic pathways will improve disease monitoring and management, especially in preventive medicine. As a result, the burden of multimorbidity and the burden of health care will benefit. The purpose of this Special Issue is to explore the metabolic pathways of epidemiological nutrition in public health. Original articles, systematic reviews, reviews, mini reviews, and clinical trial articles that provide additional knowledge on the topic of “Epidemiology, Nutrition and Metabolism” (Volume II) will be welcome.

Dr. Roberta Zupo
Dr. Maria Lisa Clodoveo
Prof. Dr. Vincenzo Solfrizzi
Dr. Giuseppe Lisco
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Metabolites is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • nutrition
  • epidemiology
  • dietary intake
  • foods
  • micronutrients
  • biomarkers
  • metabolism

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Related Special Issue

Published Papers (1 paper)

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12 pages, 1286 KiB  
Systematic Review
Dietary Intake of Polyphenols and All-Cause Mortality: A Systematic Review with Meta-Analysis
by Roberta Zupo, Fabio Castellana, Giuseppe Lisco, Filomena Corbo, Pasquale Crupi, Rodolfo Sardone, Francesco Panza, Madia Lozupone, Mariangela Rondanelli and Maria Lisa Clodoveo
Metabolites 2024, 14(8), 404; https://doi.org/10.3390/metabo14080404 - 25 Jul 2024
Cited by 1 | Viewed by 1346
Abstract
Polyphenols are secondary metabolites found in plants, foods, and drinks, occurring in small quantities and showcasing antioxidant and anti-inflammatory qualities. The primary polyphenols consist of flavonoids, phenolic acids, stilbenes, and lignans. However, there is currently no comprehensive quantitative analysis of epidemiological data on [...] Read more.
Polyphenols are secondary metabolites found in plants, foods, and drinks, occurring in small quantities and showcasing antioxidant and anti-inflammatory qualities. The primary polyphenols consist of flavonoids, phenolic acids, stilbenes, and lignans. However, there is currently no comprehensive quantitative analysis of epidemiological data on overall death rates. This systematic review with meta-analysis aims to identify the exposure–response relationship between dietary polyphenol intake and all-cause mortality. The literature was reviewed from its earliest study to May 2024, utilizing six distinct electronic databases. No specific criteria were used to choose participants based on the recruiting environment, their general health condition, country, or ethnicity. The inclusion criteria for studies were as follows: a longitudinal design, exposure to dietary polyphenols, all-cause mortality as the outcome, and hazard risk (HR) as the impact measure. The Newcastle–Ottawa Scale was used to evaluate the methodological rigor of the study. The hazard risks (HRs) and 95% confidence intervals (CIs) were estimated by pooling data using common effects models. A protocol has been registered on PROSPERO with the identification number CRD42024545524. The meta-analysis comprised seven cohort studies that involved 178,657 adult people aged 18 years and older. These studies examined the relationship between total dietary polyphenol consumption and the risk of all-cause death. The recruitment settings exclusively used community-based approaches, with a preference for Europe (71%) in terms of geographic distribution. The study’s quality was assessed to be moderate to high. The meta-analysis showed consistent evidence that increased dietary exposure to polyphenols reduces the risk of all-cause mortality by 7% (HR 0.93, 95% CI 0.91–0.95, I2: 48%). Pooled data from the available evidence consistently show that individuals exposed to an antioxidant diet rich in polyphenol sources may be at lower risk of all-cause mortality. Full article
(This article belongs to the Special Issue Epidemiology, Nutrition and Metabolism, 2nd Edition)
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