Role of Polyphenols and Other Phytochemicals in Prevention and Therapy of Civilization Diseases II
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Natural Products Chemistry".
Deadline for manuscript submissions: closed (30 April 2022) | Viewed by 2062
Special Issue Editors
2. Silesia LabMed: Centre for Research and Implementation, Katowice, Poland
Interests: use of natural product in the treatment in neoplastic diseases; mechanism of biological activity of natural compounds
Special Issues, Collections and Topics in MDPI journals
Interests: natural bioactive compounds; honeybee products; flavonoids; polyphenols; chemoprevention; cell cycle; cancer biology; apoptosis; cytopathology
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Never has so much attention been paid by scientific world to civilization diseases as it is at present. Even nowadays, during COVID-19 pandemic, we are observing numerous reports of comorbidities. One of them are civilization diseases, including cancer, chronic obstructive pulmonary disease, asthma, Alzheimer's, arthritis, stroke, heart disease, hypertensive disease, atherosclerosis, chronic liver disease or cirrhosis, type 2 diabetes, metabolic syndrome, chronic renal failure, osteoporosis, depression, gastric ulcer, obesity and overweight. On the other hand, scientists are constantly looking for new drugs, and they pay special attention to the use of natural products, especially phytochemicals and polyphenols.
Phytochemical is a broad term meaning plant chemical referring to a wide variety of compounds that occur naturally in plants. Polyphenols are secondary metabolites of plants. They are abundant micronutrients in our diet, and evidence for their role in the prevention of degenerative diseases is emerging. The health effects of polyphenols and other phytochemicals depend on the amount consumed and on their bioavailability. There are many reports of positive effects of these natural agents on cells in vitro, in vivo, such as anti-inflammatory, antibacterial, anti-cancer, antioxidant and others. Moreover, there are promising strategies implemented already in use natural compounds to treat metabolic disorders. Multiple research show mechanisms of activity of phytochemicals and polyphenols. There are (but not limited to) potential modulation of cancer initiation and growth, cellular differentiation, apoptosis and autophagy, angiogenesis, and metastatic dissemination, migration inhibition.
In this special issue, we would like to focus on polyphenols and other phytochemicals, as prospect agents in treat of diseases of civilization and lifestyle.
Potential topics (not limited to):
- Effects of natural products and derivatives (focus on phytochemicals and polyphenols) on nutrition and diet on lifestyle diseases
- New research of influence polyphenols and mechanism of their activity in order to treat obesity, cancer, diabetes, asthma and others
- New derivatives of phytochemicals with potential bioactive, their extraction and synthesis and bioactivity
- Molecular mechanism of polyphenols activity in civilization diseases
- Potential effect of phytochemicals in cancer
Dr. Robert Kubina
Dr. Agata Kabała-Dzik
Guest Editors
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Keywords
- natural products
- natural compounds
- new compounds
- phytochemicals
- diseases of civilization and lifestyle
- prevention and therapy of civilization diseases
- bioavailability of phytochemicals
- role of phytochemical in inflammatory process
- the health benefits of phytochemicals
- mechanisms of action
- functional foods and nutraceuticals
- bioactivity
- new methodologies and procedures
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