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Nanomaterials
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Advanced Nanomaterials for Bacterial Detection and Antibacterial Applications
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Advanced Nanomaterials for Bacterial Detection and Antibacterial Applications

A special issue of Nanomaterials (ISSN 2079-4991). This special issue belongs to the section "Biology and Medicines".

Deadline for manuscript submissions: closed (30 September 2023) | Viewed by 3289

Special Issue Editors

Prof. Dr. Yuanhong Xu

E-Mail Website
Guest Editor
Institute of Biomedical Engineering, College of Life Sciences, Qingdao University, Qingdao 266071, China
Interests: nanomaterials for bacterial detection and antibacterial applications
Prof. Dr. Jing Sun

E-Mail Website
Guest Editor
State Key Laboratory of Supramolecular Structure, Materials College of Chemistry, Jilin University, Changchun 130012, China
Interests: bioinspired polymers that mimic the structure of natural proteins such as polypeptides and polypeptides; self assembly of the block copolymers; antimicrobial polymers; drug delivery; smart hydrogels

Special Issue Information

Dear Colleagues,

Antibiotic resistance and pathogenic bacteria monitoring are two main challenges in clinical diagnostics and the treatment of bacteria. To conquer these issues, many new materials and novel technologies have been explored. Among them, nanomaterials are capable of acting not only as promising alternatives towards antibiotics due to their facile synthesis methods, rich-sourced precursors, broad-spectrum sterilization, and low drug resistance but also as efficient probes and modifiers for developing easy and fast powerful monitoring strategies such as electrochemistry and fluorescence for pathogen monitoring based on their features of outstanding conductivity or optical properties.

The purpose of the present Special Issue is to elucidate the state-of-the-art innovations of this growing research field from a fundamental and application perspective. The key issues on monitoring and combating pathogenic bacteria utilizing nanomaterials should be given attention in view of their design, modification, mechanism, and application. Research papers dealing with experimental studies as well as simulation and modeling for the fabrication and study of the properties of nanomaterials for bacterial detection and antibacterial applications are welcomed.

For this Special Issue, original research articles and reviews are welcome. We welcome the submission of full papers, communications, and reviews. Potential topics include, but are not limited to, the following:

  • Antibacterial nanomaterials such as quantum dots, two-dimensional materials, MOFs, single-atom nanomaterials, polymer nanocomposites, and nanozymes;
  • Experimental studies as well as simulation for the design, modification, mechanisms, and application of antibacterial nanomaterials;
  • Nanomaterials in bacteria monitoring including electrochemical sensing, optical sensing, fluorescence imaging, nucleic acid-based detection, serological analysis, etc.

Prof. Dr. Yuanhong Xu
Prof. Dr. Jing Sun
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nanomaterials is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • nanostructure(s)
  • nanomaterials
  • quantum dots
  • electrochemical imaging
  • fluorescence imaging
  • two-dimensional materials
  • metal–organic frameworks
  • nanozymes
  • polymer nanocomposites
  • mechanism
  • nucleic acid
  • serological analysis

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Published Papers (1 paper)

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Research

18 pages, 8960 KiB  
Article
Primary Amine Functionalized Carbon Dots for Dead and Alive Bacterial Imaging
by Yuting Liu, Di Zhong, Lei Yu, Yanfeng Shi and Yuanhong Xu
Nanomaterials 2023, 13(3), 437; https://doi.org/10.3390/nano13030437 - 21 Jan 2023
Cited by 13 | Viewed by 2797
Abstract
Small molecular dyes are commonly used for bacterial imaging, but they still meet a bottleneck of biological toxicity and fluorescence photobleaching. Carbon dots have shown high potential for bio-imaging due to their low cost and negligible toxicity and anti-photobleaching. However, there is still [...] Read more.
Small molecular dyes are commonly used for bacterial imaging, but they still meet a bottleneck of biological toxicity and fluorescence photobleaching. Carbon dots have shown high potential for bio-imaging due to their low cost and negligible toxicity and anti-photobleaching. However, there is still large space to enhance the quantum yield of the carbon quantum dots and to clarify their mechanisms of bacterial imaging. Using carbon dots for dyeing alive bacteria is difficult because of the thick density and complicated structure of bacterial cell walls. In this work, both dead or alive bacterial cell imaging can be achieved using the primary amine functionalized carbon dots based on their small size, excellent quantum yield and primary amine functional groups. Four types of carbon quantum dots were prepared and estimated for the bacterial imaging. It was found that the spermine as one of precursors can obviously enhance the quantum yield of carbon dots, which showed a high quantum yield of 66.46% and high fluorescence bleaching-resistance (70% can be maintained upon 3-h-irradiation). Furthermore, a mild modifying method was employed to bound ethylenediamine on the surface of the spermine–carbon dots, which is favorable for staining not only the dead bacterial cells but also the alive ones. Investigations of physical structure and chemical groups indicated the existence of primary amine groups on the surface of spermine–carbon quantum dots (which own a much higher quantum yield) which can stain alive bacterial cells visibly. The imaging mechanism was studied in detail, which provides a preliminary reference for exploring efficient and environment-friendly carbon dots for bacterial imaging. Full article
(This article belongs to the Special Issue Advanced Nanomaterials for Bacterial Detection and Antibacterial Applications)
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