Gold Nanoparticles as Host Nanosystems
A special issue of Nanomaterials (ISSN 2079-4991). This special issue belongs to the section "Synthesis, Interfaces and Nanostructures".
Deadline for manuscript submissions: closed (31 May 2021) | Viewed by 9940
Special Issue Editor
Special Issue Information
Dear colleagues,
Host nanosystems based on gold nanoparticles enjoy a sustained development because of the synthetic flexibility allowed by the self-assembled nature of the organic shell coating the nanoparticles. Indeed, gold nanoparticles can be engineered into versatile hosting systems acting as exo-receptors by proper selection of the functional groups and/or recognition units displayed at the outer monolayer surface. Gold nanoparticles can also act as endo-receptors in which the synergistic combination of hydrophobic and other non-covalent interactions provides the driving force for small molecule recognition by the monolayer inner regions. In addition, host nanosystems based on gold nanoparticles, with sizes that compare to those of many naturally evolved objects such as protein, protein complexes, nucleic acid–protein complexes or cellular substructures, have prompted researchers to push the target guests beyond the limit of small molecules to include biopolymers, lipid aggregates, and functionalized surfaces. The rich diversity of guests that can be targeted by these host nanosystems has allowed their applications as drug and gene delivery vectors, platforms for chemical and biological sensing, building blocks in supramolecular chemistry, and probes to interrogate the complexity of recognition events at the nanoscale, to mention a few examples.
This Special Issue aims at covering all aspects of the synthesis, development, and implementation of gold-nanoparticle-based host nanosystems for a span of guests including small molecules, polymers, and biopolymers. Studies aimed at understanding how the host–guest chemistry of gold nanoparticles is controlled by the properties of their coating shell are also welcomed.
Contributions to the issue include full papers, communications, and reviews.
Dr. Paolo Pengo
Guest Editor
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Keywords
- Gold nanoparticles
- Gold nanoparticle receptors
- Gold nanoparticles hosts
- Host-guest chemistry
- Drug delivery
- Sensing
- Nanoparticles monolayer
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