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Nutrients
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Dietary Interventions against Age-Related Vascular Pathologies
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Dietary Interventions against Age-Related Vascular Pathologies

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Nutritional Epidemiology".

Deadline for manuscript submissions: closed (10 November 2023) | Viewed by 18215

Special Issue Editors

Dr. Stefano Tarantini

E-Mail Website
Guest Editor
Department of Biochemistry and Molecular Biology, Health Sciences Center, Vascular Cognitive Impairment and Neurodegeneration Program, Oklahoma Center for Geroscience and Healthy Brain Aging, University of Oklahoma, Oklahoma City, OK 73019, USA
Interests: hypertension; dietary interventions; high-fat diet; senescence; reactive oxygen species; senolytics; vascular biology; vascular imaging; cerebrovascular circulation; vascular physiology; microcirculation; cognitive aging; cerebral blood flow; laser Doppler flowmetry; mitochondria function
Special Issues, Collections and Topics in MDPI journals
Prof. Dr. Rafael De Cabo

E-Mail Website
Guest Editor
National Institute on Aging, 251 Bayview Blvd., Suite 100/Room 5C214, Baltimore, MD 21224, USA
Interests: aging; mitochondria; resveratrol supplementation; vascular biology

Special Issue Information

Dear Colleagues,

The number of adults above 65 years of age is rapidly increasing worldwide. Aging individuals are more likely to suffer from cardiovascular disease, hypertension, atherosclerosis, and heart pathologies. Along with aging, dietary habits are an important modulating factor that may affect a person's likelihood of developing cardiovascular disease. Growing evidence has shown that many deleterious dietary habits (i.e., the consumption of processed foods and high amounts of salt, sugar, and trans fats, etc.) can exacerbate cardiovascular aging and impair cellular function. Novel research in dietary and lifestyle interventions are critical in developing clinical strategies to delay vascular aging and prevent cardiovascular disease.

Dr. Stefano Tarantini
Prof. Dr. Rafael De Cabo
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • dietary interventions
  • cardiovascular health
  • hypertension
  • microvasculature
  • aging

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Published Papers (2 papers)

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Review

25 pages, 1638 KiB  
Review
Role of Vitamin D Deficiency in the Pathogenesis of Cardiovascular and Cerebrovascular Diseases
by Éva Pál, Zoltán Ungvári, Zoltán Benyó and Szabolcs Várbíró
Nutrients 2023, 15(2), 334; https://doi.org/10.3390/nu15020334 - 9 Jan 2023
Cited by 42 | Viewed by 7973
Abstract
Deficiency in vitamin D (VitD), a lipid-soluble vitamin and steroid hormone, affects approximately 24% to 40% of the population of the Western world. In addition to its well-documented effects on the musculoskeletal system, VitD also contributes importantly to the promotion and preservation of [...] Read more.
Deficiency in vitamin D (VitD), a lipid-soluble vitamin and steroid hormone, affects approximately 24% to 40% of the population of the Western world. In addition to its well-documented effects on the musculoskeletal system, VitD also contributes importantly to the promotion and preservation of cardiovascular health via modulating the immune and inflammatory functions and regulating cell proliferation and migration, endothelial function, renin expression, and extracellular matrix homeostasis. This brief overview focuses on the cardiovascular and cerebrovascular effects of VitD and the cellular, molecular, and functional changes that occur in the circulatory system in VitD deficiency (VDD). It explores the links among VDD and adverse vascular remodeling, endothelial dysfunction, vascular inflammation, and increased risk for cardiovascular and cerebrovascular diseases. Improved understanding of the complex role of VDD in the pathogenesis of atherosclerotic cardiovascular diseases, stroke, and vascular cognitive impairment is crucial for all cardiologists, dietitians, and geriatricians, as VDD presents an easy target for intervention. Full article
(This article belongs to the Special Issue Dietary Interventions against Age-Related Vascular Pathologies)
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28 pages, 517 KiB  
Review
Nutrition Strategies Promoting Healthy Aging: From Improvement of Cardiovascular and Brain Health to Prevention of Age-Associated Diseases
by Monika Fekete, Zsofia Szarvas, Vince Fazekas-Pongor, Agnes Feher, Tamas Csipo, Judit Forrai, Norbert Dosa, Anna Peterfi, Andrea Lehoczki, Stefano Tarantini and Janos Tamas Varga
Nutrients 2023, 15(1), 47; https://doi.org/10.3390/nu15010047 - 22 Dec 2022
Cited by 30 | Viewed by 9319
Abstract
Background: An increasing number of studies suggest that diet plays an important role in regulating aging processes and modulates the development of the most important age-related diseases. Objective: The aim of this review is to provide an overview of the relationship between nutrition [...] Read more.
Background: An increasing number of studies suggest that diet plays an important role in regulating aging processes and modulates the development of the most important age-related diseases. Objective: The aim of this review is to provide an overview of the relationship between nutrition and critical age-associated diseases. Methods: A literature review was conducted to survey recent pre-clinical and clinical findings related to the role of nutritional factors in modulation of fundamental cellular and molecular mechanisms of aging and their role in prevention of the genesis of the diseases of aging. Results: Studies show that the development of cardiovascular and cerebrovascular diseases, neurodegenerative diseases, cognitive impairment and dementia can be slowed down or prevented by certain diets with anti-aging action. The protective effects of diets, at least in part, may be mediated by their beneficial macro- (protein, fat, carbohydrate) and micronutrient (vitamins, minerals) composition. Conclusions: Certain diets, such as the Mediterranean diet, may play a significant role in healthy aging by preventing the onset of certain diseases and by improving the aging process itself. This latter can be strengthened by incorporating fasting elements into the diet. As dietary recommendations change with age, this should be taken into consideration as well, when developing a diet tailored to the needs of elderly individuals. Future and ongoing clinical studies on complex anti-aging dietary interventions translating the results of preclinical investigations are expected to lead to novel nutritional guidelines for older adults in the near future. Full article
(This article belongs to the Special Issue Dietary Interventions against Age-Related Vascular Pathologies)
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