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Effects of Nutrient Intake on Cardiovascular Disease

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Clinical Nutrition".

Deadline for manuscript submissions: 15 January 2025 | Viewed by 831

Special Issue Editor


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Guest Editor
Department of Physiology, Wayne State University, Detroit, MI, USA
Interests: cardiovascular disease; salt sensitive hypertension; exercise training
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The burden of cardiovascular disease is a global issue leading to a disproportionate number of premature and preventable deaths. Dietary habits and nutrient intake that influence metabolic health are well recognized as major modifiable factors that contribute to this risk. Despite, or because of, cardiovascular benefits displayed by GLP-1 agonists and SGLT2 antagonists, the role of a balanced and appropriate dietary intake as a primary or valuable adjunct to pharmacological therapy is crucial. The disproportional prevalence of cardiovascular disease in less affluent countries makes attention to dietary intervention for obtaining culturally and regionally optimal dietary patterns even more important.

This Special Issue is designed to provide a platform to examine foods and/or nutrients that impact cardiovascular health and disease. In addition to pathophysiological and pharmacological investigations, studies that address cultural, regional/national and socioeconomic factors that influence dietary patterns and availability of key nutrients are welcome.

We will also welcome original articles as well as narrative and systematic reviews.

Prof. Dr. Noreen F. Rossi
Guest Editor

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Keywords

  • dietary patterns
  • nutrient intake
  • dietary habits
  • cardiovascular risk
  • cardiovascular health
  • disease prevention
  • factors

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Published Papers (1 paper)

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Research

14 pages, 2340 KiB  
Article
Healthy Dietary Pattern Cycling Affects Gut Microbiota and Cardiovascular Disease Risk Factors: Results from a Randomized Controlled Feeding Trial with Young, Healthy Adults
by Yu Wang, Tzu-Wen L. Cross, Stephen R. Lindemann, Minghua Tang and Wayne W. Campbell
Nutrients 2024, 16(21), 3619; https://doi.org/10.3390/nu16213619 - 25 Oct 2024
Viewed by 655
Abstract
Background: Previous research demonstrates that adopting, abandoning, and re-adopting (i.e., cycling) a healthy dietary pattern (HDP) improved, reverted, and re-improved cardiovascular disease (CVD) risk factors. In addition, changes in CVD risk factors are associated with dietary modifications of gut microbiota. Objective: We sought [...] Read more.
Background: Previous research demonstrates that adopting, abandoning, and re-adopting (i.e., cycling) a healthy dietary pattern (HDP) improved, reverted, and re-improved cardiovascular disease (CVD) risk factors. In addition, changes in CVD risk factors are associated with dietary modifications of gut microbiota. Objective: We sought to assess the effects of cycling an HDP on gut microbiota and CVD risk factors. Methods: Retrospectively, we used data from a randomized controlled, crossover trial with three 3-week controlled dietary interventions, each separated by a 5-week period of participant-chosen, uncontrolled food intake. Seventeen participants (10 males, 7 females, age 26 ± 4 years old, BMI 23 ± 3 kg/m2) all consumed intervention diets that followed healthy U.S.-style dietary patterns. Gut microbiota composition and cardiovascular risk factors were measured before and after each HDP. Results: Repeatedly adopting and abandoning an HDP led to a cycling pattern of changes in the gut microbial community and taxonomic composition. During the HDP cycles, relative abundances of several bacterial taxa (e.g., Collinsella, Mediterraneibacter, Romboutsia, and Dorea) decreased and returned to baseline repeatedly. Similar HDP cycling occurred for multiple CVD risk factors (i.e., serum total cholesterol and LDL-C concentrations). Consistent negative associations were observed between changes in Mediterraneibacter or Collinsella and serum total cholesterol/HDL-C ratio. Conclusions: These results support previous findings that HDP cycling affected multiple CVD risk factors and expand the HDP cycling phenomenon to include several bacterial taxa. Young adults are encouraged to adopt and sustain a healthy dietary pattern to improve cardiovascular health, potentially through modifying gut microbiota composition. Full article
(This article belongs to the Special Issue Effects of Nutrient Intake on Cardiovascular Disease)
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