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Nutritional Management in Gastrointestinal Diseases

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Clinical Nutrition".

Deadline for manuscript submissions: closed (25 July 2024) | Viewed by 4894

Special Issue Editor


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Guest Editor
1. Gastroenterology, Hepatology and Nutrition Unit, University Hospital San Jorge, 22004 Huesca, Spain
2. Department of Medicine, Faculty of Health and Sport Sciences, University of Zaragoza, 22002 Huesca, Spain
3. Aragon Health Research Institute (IIS Aragón), 50009 Zaragoza, Spain
Interests: nutritional management; nutritional support; motility disorders; malabsorption; inflammatory bowel disease; celiac disease
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Special Issue Information

Dear Colleagues,

Digestive tract diseases frequently lead to states of malnutrition due to various causes. These include swallowing disorders (e.g., neurodegenerative disease or achalasia), a set of disorders leading to states of malassimilation of nutrients (maldigestion and/or malabsorption), protein-losing enteropathy (e.g., Menetrier's disease, lymphangiectasia, or fistulas), or others that, in addition to compromising nutrient supply, lead to increased metabolic demands due to severe inflammation (e.g., severe caustic esophagitis, severe acute pancreatitis, or inflammatory bowel disease). Liver diseases, especially steatotic liver disease associated with metabolic dysfunction or liver disease caused by harmful use of alcohol, constitute an important chapter, as do the consequences of surgery performed on the upper (e.g., Dumping syndrome) and lower digestive tracts (e.g., water losses and electrolytes through ostomies or short bowel syndrome). Bariatric surgery itself or extensive bowel resections lead to states of malnutrition that are challenging for the clinician and must be managed by interdisciplinary teams. Neglecting the nutritional status of our patients can have a very negative impact on outcomes while increasing healthcare costs. In contrast, careful and diligent attention to patients' nutritional needs will positively impact clinical outcomes. The major aim of this Special Issue is to provide an overview of the nutritional burden of digestive diseases and how to approach their management with the involvement of gastroenterologists, hepatologists, nurses, dietitians, and experts in intensive care medicine, as appropriate.

Contents:

Nutritional Principles and Assessment of Gastrointestinal Patients

  • Physiologic impairments caused by protein–energy malnutrition.
  • Nutritional assessment techniques.
  • Nutritional support for hospitalized patients: basic principles.

Nutritional Management in Specific Disease States

  • Nutritional support in diseases that impair swallowing mechanisms.
  • Nutritional management of patients with severe esophagitis by caustics.
  • Nutritional support in diseases that cause malassimilation of nutrients due to maldigestion or malabsorption.
  • Nutritional management of patients with protein-losing enteropathy.
  • Nutritional management of local and systemic complications of inflammatory bowel disease.
  • Water, electrolyte, and nutritional management of severe inflammatory states associated with necrotizing pancreatitis.
  • How to manage exocrine pancreatic insufficiency?
  • Management of severe diarrhea associated with fistulas and ostomies.
  • Nutritional management of patients undergoing radiation therapy.
  • Modern approach to steatotic liver disease associated with metabolic dysfunction (MASDL).
  • Management of nutritional complications of alcohol-induced liver disease.
  • Nutritional approach to patients hospitalized with decompensated alcoholic liver disease.

Comprehensive Approach to the Nutritional Sequelae of Digestive Tract Surgery

  • Perioperative nutritional management in patients with major abdominal surgery.
  • How to manage nutritional complications from upper gastrointestinal tract surgery.
  • Bariatric surgery: indications, complications, and postoperative nutritional approach.
  • Modern approach to nutritional complications after lower digestive tract surgery.
  • Comprehensive approach to short bowel syndrome.

Intervention of the Dietitian as a Support for Digestive Diseases Treated on an Outpatient Basis

  • Nutritional and holistic approach to patients with eating disorders.
  • Clinical and dietary management of obesity.
  • Dietary intervention in patients with eosinophilic esophagitis.
  • Dietary intervention in patients with gastroesophageal reflux disease.
  • Dietary intervention in functional dyspepsia
  • Dietary intervention in gastroparesis
  • Dietary intervention in Dumping syndrome.
  • Counseling and monitoring of the diet in patients with celiac disease and other gluten-related disorders.
  • Dietary intervention in patients with malabsorption and/or intolerance to simple sugars.
  • Dietary and nutritional advice for patients with irritable bowel syndrome.
  • Dietary intervention in diverticular disease.
  • Dietary and nutritional counseling in patients with benign anorectal pathology.
  • Dietary patterns and dysbiosis in "modern" Western society.

Prof. Dr. Miguel Montoro
Guest Editor

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Keywords

  • digestive tract diseases
  • diarrhea
  • inflammatory bowel disease
  • short bowel syndrome
  • celiac disease and other gluten-related disorders
  • steatotic liver disease associated with metabolic dysfunction
  • malnutrition
  • nutritional support
  • nutritional management

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Published Papers (2 papers)

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Research

17 pages, 2535 KiB  
Article
Comparison of Dietary Supplementation with Krill Oil, Fish Oil, and Astaxanthin on an Experimental Ethanol-Induced Gastric Ulcer Model: A Biochemical and Histological Study
by Esra Tansu Sarıyer, Murat Baş, Hatice Çolak, Naziye Özkan Yenal, Özlem Unay Demirel and Meral Yüksel
Nutrients 2024, 16(20), 3426; https://doi.org/10.3390/nu16203426 - 10 Oct 2024
Viewed by 1443
Abstract
Background/Objectives: Despite advances in ulcer treatment research, the search for new, safe, and effective strategies for preventing and treating ulcer diseases persists. Methods: In this study, the protective effects of dietary supplementation with krill oil (KO), fish oil (FO), and astaxanthin (ASX) on [...] Read more.
Background/Objectives: Despite advances in ulcer treatment research, the search for new, safe, and effective strategies for preventing and treating ulcer diseases persists. Methods: In this study, the protective effects of dietary supplementation with krill oil (KO), fish oil (FO), and astaxanthin (ASX) on an ethanol-induced gastric ulcer model were compared during biochemical and histological observations. Sprague–Dawley (n = 64) rats randomly divided into four groups—normal control (vehicle), KO, FO, and ASX groups—received the supplements via the orogastric route at a rate of 2.5% (v/w) of their daily feed consumption for 4 weeks. Then, ulcer induction was performed with ethanol. Results: The ulcer group showed increased levels of malondialdehyde (MDA), chemiluminescence (CL), and myeloperoxidase (MPO) activity and decreased levels of glutathione in the gastric tissues. While KO, FO, and ASX supplementation decreased chemiluminescence levels in the ulcer group, only ASX supplementation decreased MDA levels and MPO activity. Conclusions: In conclusion, supplementation with KO or FO has a similar protective effect against ethanol-induced ulcer damage, as it inhibits ROS formation and reduces lipid peroxidation. However, ASX supplementation has a higher protective effect than KO or FO supplementations against experimental ethanol-induced gastric lesions in rats, as it inhibits ROS formation and reduces neutrophil infiltration and lipid peroxidation. Full article
(This article belongs to the Special Issue Nutritional Management in Gastrointestinal Diseases)
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22 pages, 1685 KiB  
Article
Beneficial Effect of Heat-Killed Lactic Acid Bacterium Lactobacillus johnsonii No. 1088 on Temporal Gastroesophageal Reflux-Related Symptoms in Healthy Volunteers: A Randomized, Placebo-Controlled, Double-Blind, Parallel-Group Study
by Yasuhiko Komatsu, Hiroyasu Miura, Yoshitaka Iwama and Yoshihisa Urita
Nutrients 2024, 16(8), 1230; https://doi.org/10.3390/nu16081230 - 20 Apr 2024
Cited by 1 | Viewed by 2727
Abstract
A randomized, placebo-controlled, double-blind, parallel-group clinical study was conducted to examine the effects of ingesting a heat-killed lactic acid bacterium, Lactobacillus johnsonii No. 1088 (LJ88) on temporal gastroesophageal reflux-related symptoms in healthy volunteers. A total of 120 healthy Japanese volunteers of both sexes, [...] Read more.
A randomized, placebo-controlled, double-blind, parallel-group clinical study was conducted to examine the effects of ingesting a heat-killed lactic acid bacterium, Lactobacillus johnsonii No. 1088 (LJ88) on temporal gastroesophageal reflux-related symptoms in healthy volunteers. A total of 120 healthy Japanese volunteers of both sexes, aged between 21 and 63 years, whose Frequency Scale for the Symptoms of Gastroesophageal Reflux Disease (FSSG) total score was 8 or greater, but who were not diagnosed with functional dyspepsia according to the Rome IV classification, were enrolled. They were randomly assigned to either the LJ88 or placebo group and instructed to ingest the test food (1 billion heat-killed LJ88 or placebo) once a day for six weeks. Gastroesophageal reflux-related symptoms were evaluated using FSSG scores as a primary endpoint. The Gastrointestinal Symptoms Rating Scale (GSRS), stomach state questionnaire, and serum gastrin concentration were used as secondary endpoints. In the FSSG evaluation, the heartburn score was significantly improved at 6 weeks in the LJ88 group compared to the placebo group. No severe adverse events related to the test food were observed. In conclusion, daily ingestion of heat-killed LJ88 improved temporal heartburn symptoms in non-diseased individuals. Full article
(This article belongs to the Special Issue Nutritional Management in Gastrointestinal Diseases)
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