Nanotechnology-Enabled Strategies to Enhance Topical Bioavailability, 3rd Edition
A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Nanomedicine and Nanotechnology".
Deadline for manuscript submissions: closed (31 October 2024) | Viewed by 1143
Special Issue Editors
Interests: topical bioavailability; solid-state preformulation; nanoparticles
Special Issues, Collections and Topics in MDPI journals
2. Research Center for Pharmaco-Toxicological Evaluations, Faculty of Pharmacy, Victor Babes University of Medicine and Pharmacy, 2nd Eftimie Murgu Sq., 300041 Timisoara, Romania
Interests: nanodelivery systems; stimuli-controlled release; bioavailability; in vitro assessments using cell monolayer and 3D human reconstructed microtissues
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Special Issue Information
Dear Colleagues,
The design and development of new topical formulations are trending topics, especially in the biomedical field, as they can be conceived to not only address protective and cosmetic needs, but also target therapeutic outcomes.
Because one of the main functions of human skin is protection—the skin acts as a barrier to the penetration of various external factors—the penetration of active substances through the skin is impaired, thus limiting their therapeutic potential. To overcome this, innovative strategies are required to increase skin permeability by means of penetration promoters.
In this regard, modern nanotechnology-based formulations are under development, such as derived liposomal formulations (transferosomes, ethosomes, cubosomes, nanostructured lipid carriers or other lipid-based nanocarriers), nanogels, nanoemulsions, cyclodextrin-based formulations and other modern approaches.
For the current Special Issue, original research and review articles addressing recent advances in nanopharmaceutical formulations with enhanced topical bioavailability and complex biological in vitro and/or in vivo profiles are welcome for submission.
Dr. Lenuţa Şuta
Dr. Claudia Geanina Watz
Guest Editors
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Keywords
- nanotechnology-based formulations
- drug-in nanocarriers
- cyclodextrin-in nanocarriers
- polymer-based nanocarriers
- topical drug-delivery systems
- bioavailability enhancement
- drug release in vitro and in vivo
- skin models
- biological assessments
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