Nanocarriers for Drug Delivery in Tissue Engineering
A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Nanomedicine and Nanotechnology".
Deadline for manuscript submissions: closed (31 December 2023) | Viewed by 3138
Special Issue Editors
Interests: drug delivery; micro/nano carriers; new technologies for drug carriers development; innovative drug carriers; biopolymers; liposomes; nanogels
Special Issues, Collections and Topics in MDPI journals
Interests: drug delivery systems; nanomedicine; tissue engineering; microfluidics technology; lipid nanoparticles; liposomes; polyesters-based carriers
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
We are pleased to invite you to participate in a Special Issue of the Pharmaceutics journal entitled “Nanocarriers for Drug Delivery in Tissue Engineering”.
Despite good progress made recently by tissue engineering in developing synthetic extracellular matrices, the next big challenge will be the development of engineered nano-carriers that can be directly incorporated into 3D scaffolds to promote the assembly of an advanced microenvironment in which controlled or sustained delivery of growth factors or other bioactive molecules is achieved in a designed spatiotemporal fashion. Indeed, nano-carriers can advantageously modify the pharmacokinetic profile of bioactive molecules and control their concentration in specific target tissues. Moreover, nanocarrier inclusion within scaffolds can be used to reproduce more complex biological environments. On the other hand, issues concerning advanced processes and technologies to fabricate suitable nano-carriers in terms of relievable chemical-physical properties (e.g., low cytotoxicity and high encapsulation efficiency) or their functionalization with standardized protocols have become crucial for the future of tissue engineering.
This Special Issue aims to deepen nanocarrier manufacturing processes, their characterization, and embedding protocols to enhance and standardize local drug delivery within 3D scaffolds aimed at tissue engineering or regenerative medicine. The primary purpose of this Issue is to examine novel manufacturing processes for synthesizing advanced nanocarriers and their characterization, including morphological (TEM and SEM), granulometric (DLS and NTA), and kinetic analyses. Finally, cytotoxicity and potential biological effects on in vitro and in vivo 3D bioengineered models will also be the focus of this research topic.
In this Special Issue, original research articles and reviews are welcome. Research areas may include (but not limited to) the following:
- Development of new delivery nano-systems for tissue engineering
- Strategies to improve the encapsulation efficiency of growth factors or bioactive molecules for tissue engineering protocols
- Innovative manufacturing processes for nano-carrier production.
We look forward to receiving your contributions.
Prof. Dr. Giovanna Della Porta
Dr. Erwin Pavel Lamparelli
Guest Editors
Manuscript Submission Information
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Keywords
- drug delivery systems
- controlled release
- growth factors encapsulation
- Innovative nanoencapsulation techniques
- tissue engineering
- nanomedicine
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