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Photonics
Special Issues
Advanced Technologies in Biophotonics and Medical Physics
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Advanced Technologies in Biophotonics and Medical Physics

A special issue of Photonics (ISSN 2304-6732). This special issue belongs to the section "Biophotonics and Biomedical Optics".

Deadline for manuscript submissions: 20 June 2025 | Viewed by 2080

Special Issue Editors

Dr. Yue Zhao

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Guest Editor
Associate Professor, School of Physics and Optoelectronic Engineering, Shandong University of Technology, Zibo 255049, China
Interests: biological and medical physics; biophotonics; biomedical optics; photoacoustic imaging; X-ray-induced acoustic computed tomography
Special Issues, Collections and Topics in MDPI journals
Dr. Haigang Ma

E-Mail Website
Guest Editor
Associate Professor, School of Electronic and Optical Engineering, Nanjing University of Science and Technology, Nanjing 210094, China
Interests: photoacoustic imaging technology; photoelectric detection and image engineering; multi-dimensional ultrasonic detection and imaging
Special Issues, Collections and Topics in MDPI journals
Dr. Yujiao Shi

E-Mail Website
Guest Editor
Associate Professor, College of Biophotonics, Institute of Life Science, South China Normal University, Guangzhou, China
Interests: biomedical imaging; photoacoustic imaging
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

In recent years, an increasing number of optical techniques have been applied in the field of biophotonics and medical physics, playing a significant role in both biomedical research and clinical diagnosis. Traditional medical imaging methods present many disadvantages such as damage, low sensitivity and low resolution.

Optical technology such as photoacoustic imaging and optical coherent tomography provide high-contrast and high-resolution images directly linked to the diagnosis. Laser-induced breakdown spectroscopy and photoacoustic spectroscopy can provide chemical composition and spectral information. Radiation-induced ultrasound imaging such as X-ray-induced acoustic computed tomography has important application prospects for low-dose clinical detection.

Therefore, non-destructive optical technologies and low-dose imaging techniques will be one of the main trends in the future. We would like to receive manuscripts or review articles on the latest research progress in this field, highlighting the recent advances in biophotonics and medical physics. We believe your work will greatly benefit our readers and make a great contribution to the development in this field.

Dr. Yue Zhao
Dr. Haigang Ma
Dr. Yujiao Shi
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Photonics is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • photoacoustic imaging and spectroscopy
  • optical coherent tomography
  • laser-induced breakdown spectroscopy
  • biomedical optics and biophotonics
  • X-ray-induced acoustic computed tomography
  • radiation-induced ultrasound imaging
  • biological and medical physics
  • basic research and translational research.

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Published Papers (3 papers)

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Research

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14 pages, 6634 KiB  
Article
Method of Tissue Differentiation Based on Changes in Tissue Optical Properties Under Mechanical Stress Estimated with Optical Coherence Tomography
by Evgeny P. Sherstnev, Alexander A. Moiseev, Aleksander A. Sovetsky, Pavel A. Shilyagin, Sergey Y. Ksenofontov and Grigory V. Gelikonov
Photonics 2025, 12(2), 122; https://doi.org/10.3390/photonics12020122 - 29 Jan 2025
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Abstract
This study highlights the possibility of contrasting the differences in tissues’ mechanical properties from Optical Coherence Tomography (OCT) data without maintaining phase stability during OCT data acquisition. The proposed method is based on the rate of attenuation coefficient changes under the mechanical pressure [...] Read more.
This study highlights the possibility of contrasting the differences in tissues’ mechanical properties from Optical Coherence Tomography (OCT) data without maintaining phase stability during OCT data acquisition. The proposed method is based on the rate of attenuation coefficient changes under the mechanical pressure evaluation of the OCT data. It was shown, both on the calibrated synthetic and ex vivo biological samples, that the rate of attenuation coefficient changes observed corresponds to the sample’s mechanical properties and could be used to characterize the sample and distinguish it from other samples even if their optical properties before the pressure application are similar. This opens up the possibility to use an in vivo OCT-based system that can contrast mechanical properties without ensuring phase stability. Full article
(This article belongs to the Special Issue Advanced Technologies in Biophotonics and Medical Physics)
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11 pages, 1281 KiB  
Communication
Enhanced Thermoacoustic Imaging System with Parallel Ultrasonic Velocity Measurement for Distinguishing Types of Microwave-Absorbing Anomalies
by Wenzheng Ding and Yao Zhang
Photonics 2024, 11(10), 916; https://doi.org/10.3390/photonics11100916 - 27 Sep 2024
Viewed by 752
Abstract
Microwave-absorbing suspicious objects (MASOs) found using microwave-induced thermoacoustic imaging (MTI) can be divided into two types—endogenous (such as tumors or hematoceles) and exogenous (such as calculi or foreign bodies). These have different microwave absorption or ultrasonic velocity than normal human tissue, so MTI [...] Read more.
Microwave-absorbing suspicious objects (MASOs) found using microwave-induced thermoacoustic imaging (MTI) can be divided into two types—endogenous (such as tumors or hematoceles) and exogenous (such as calculi or foreign bodies). These have different microwave absorption or ultrasonic velocity than normal human tissue, so MTI is efficient in detecting these anomalies. However, the existing MTI techniques can only reflect morphological information, making it difficult to distinguish the type of each anomaly. In this paper, a newly enhanced MTI system composed of a multiple-element ring transducer and a parallel data acquisition system (DAS) is presented. By using ultrasonic velocity and microwave absorption measurements, where the ultrasonic velocity is mainly used as an additional parameter to reflect mechanical characteristics, the type of the detected anomaly can be identified. In our experiments, the MASO can be located through the absorption difference detected by MTI. Due to the use of multiple-element transducers and a parallel DAS, the raw data can be acquired within about 20 ms for a two-dimensional image. Additionally, the ultrasonic velocity of the MASO can be calculated from the time sequence diagram of ultrasound propagation with a maximum time error of 0.084 μs. Apart from distinguishing the type of the anomaly, the proposed ultrasonic velocity-assisted microwave-induced thermoacoustic imaging (US-MTI) system has other advantages, such as being noninvasive, and allowing rapid imaging and a large field of view, which make US-MTI a suitable modality for regular screening. Full article
(This article belongs to the Special Issue Advanced Technologies in Biophotonics and Medical Physics)
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Review

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15 pages, 3375 KiB  
Review
Review of the Fundamental Measurement Modalities in Photoacoustic Mechanical Imaging
by Xiaohan Shi, Jianqin Sun, Hua Yuan, Liming Li, Haiyang Zhang and Yue Zhao
Photonics 2025, 12(1), 90; https://doi.org/10.3390/photonics12010090 - 20 Jan 2025
Viewed by 490
Abstract
Photoacoustic (PA) imaging is a non-invasive imaging technique with high optical resolution and acoustic penetration depth, which has been widely used in medical and clinical researches. As an important part in functional PA imaging, photoacoustic mechanical imaging (PAMI) has great potential in visualizing [...] Read more.
Photoacoustic (PA) imaging is a non-invasive imaging technique with high optical resolution and acoustic penetration depth, which has been widely used in medical and clinical researches. As an important part in functional PA imaging, photoacoustic mechanical imaging (PAMI) has great potential in visualizing and understanding the local development of pathological process. This review provides lots of PA breakthroughs which have been made in elasticity detection, viscosity detection, and viscoelasticity detection through PAMI techniques. The current research problems, challenges and future development directions were discussed. Full article
(This article belongs to the Special Issue Advanced Technologies in Biophotonics and Medical Physics)
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