Unravelling the Medicinal Phytochemistry of Plants in Metabolic and Vascular Diseases and the Associated Oxidative and Inflammatory Responses

Dear Colleagues,

Metabolic and vascular diseases are among the leading non-communicable diseases that compromise the health and wellbeing of people due to their high morbidity and mortality. Epidemiological studies have shown that many metabolic and vascular diseases can co-exist because they often share underlying risk factors, which can worsen the disease conditions. Moreover, oxidative stress has been implicated as a common denominator in the development, progression and complications of metabolic and vascular diseases. Medicinal plants have often been documented as potent treatment alternatives and/or complementary therapeutic agents for many diseases, including metabolic and vascular impairments. This has been linked to their phytochemical constituents, which have diverse pharmacological profiles, including antioxidant capacity. However, it is imperative to understand the pharmacological contributions and medicinal phytochemistries of the phytoconstituents in medicinal plants, as this could encourage the more effective use of medicinal plants in the management of metabolic and vascular diseases.

This Special Issue will compile original high-quality research publications that present experimental and clinical data on the pharmacological properties of medicinal plants in metabolic and vascular diseases and associated oxidative and inflammatory responses. This collection will include studies involving the bioassay-guided recovery and characterization of possible pharmacological isolates, as well as the possible underlying bioactivity–structure relationship, which will provide insights into the medicinal phytochemistries of plants. This collection will also accommodate well-written review articles containing novel interpretations of existing and current scientific knowledge to provide greater insights into the pharmacological phytochemistries of medicinal plants used in metabolic and vascular disease treatment.

Dr. Chika Ifeanyi Chukwuma
Dr. Ochuko Lucky L. Erukainure
Guest Editors

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• phytochemicals
• pharmacological action
• oxidative stress
• metabolic diseases
• vascular diseases