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Nanomaterial-Integrated Biosensing Microdevices and Systems: Challenges and Opportunities

A special issue of Sensors (ISSN 1424-8220). This special issue belongs to the section "Biosensors".

Deadline for manuscript submissions: 15 April 2025 | Viewed by 4720

Special Issue Editor


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Guest Editor
School of Mechanical Engineering, Sichuan University, Chengdu 610065, China
Interests: integration of nanomaterial into microsystem; micromachining of carbon-MEMS and integrated microdevice; power-MEMS and on-chip integrated microsystem
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Special Issue Information

Dear Colleagues,

This Special Issue "Nanomaterial-Integrated Biosensing Microdevices and Systems: Challenges and Opportunities", aims to explore the developments and challenges in integrating nanomaterials into biosensing applications at the micro and system levels. Nanomaterials offer exceptional advantages in terms of sensitivity, specificity, and adaptability, creating new possibilities for real-time detection in medical diagnostics, environmental monitoring, and other sectors. Despite these rapid advancements, integrating these nanomaterials into functional microdevices presents hurdles such as material compatibility, stability, and scalability.

The current landscape in this field is marked by an increasing number of groundbreaking innovations, yet this is coupled with a slow rate of commercial translation. There is an expanding recognition of the technology's potential, but achieving systemic integration while maintaining robust performance remains at a bottleneck.

We invite original research papers, reviews, and case studies that cover various aspects of nanomaterials in biosensing technology, ranging from novel sensor designs to real-world applications. This Special Issue seeks to provide a multidisciplinary platform to stimulate dialogue among researchers and practitioners, aiming to expedite the journey of nanomaterial-integrated biosensing technologies from the lab to real-world applications. We highly encourage scholars in this dynamic field to contribute their valuable insights and findings.

Prof. Dr. Liang He
Guest Editor

Manuscript Submission Information

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Keywords

  • nanomaterial-integrated biosensing
  • microdevices and systems
  • medical diagnostics
  • environmental monitoring

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Published Papers (2 papers)

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Research

12 pages, 3493 KiB  
Article
Pd Nanoparticles Loaded on Cu Nanoplate Sensor for Ultrasensitive Detection of Dopamine
by Haihu Tan, Xuan Zhang, Jinpu Xie, Zengmin Tang, Sijia Tang, Lijian Xu and Pingping Yang
Sensors 2024, 24(17), 5702; https://doi.org/10.3390/s24175702 - 2 Sep 2024
Viewed by 770
Abstract
The detection of dopamine is of great significance for human health. Herein, Pd nanoparticles were loaded on Cu nanoplates (Pd/Cu NPTs) by a novel liquid phase reduction method. A novel dopamine (DA) electrochemical sensor based on the Pd NPs/Cu/glass carbon electrode (Pd/Cu NPTs/GCE) [...] Read more.
The detection of dopamine is of great significance for human health. Herein, Pd nanoparticles were loaded on Cu nanoplates (Pd/Cu NPTs) by a novel liquid phase reduction method. A novel dopamine (DA) electrochemical sensor based on the Pd NPs/Cu/glass carbon electrode (Pd/Cu NPTs/GCE) was constructed. This sensor showed a wide linear range of 0.047 mM to 1.122 mM and a low limit of detection (LOD) of 0.1045 μM (S/N = 3) for DA. The improved performance of this sensor is attributed to the obtained tiny Pd nanoparticles which increase the catalytic active sites and electrochemical active surface areas (ECSAs). Moreover, the larger surface area of two–dimensional Cu nanoplates can load more Pd nanoparticles, which is another reason to improve performance. The Pd/Cu NPTs/GCE sensor also showed a good reproducibility, stability, and excellent anti–interference ability. Full article
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15 pages, 3573 KiB  
Article
Non-Invasive Multi-Gas Detection Enabled by Cu-CuO/PEDOT Microneedle Sensor
by Arif Ullah Khan, Muhammad Tahir, Fazal Ul Nisa, Mizna Naseem, Iqra Shahbaz, Zeyu Ma, Zilu Hu, Abdul Jabbar Khan, Muhammad Sabir and Liang He
Sensors 2024, 24(11), 3623; https://doi.org/10.3390/s24113623 - 4 Jun 2024
Viewed by 970
Abstract
Metal-oxide-based gas sensors are extensively utilized across various domains due to their cost-effectiveness, facile fabrication, and compatibility with microelectronic technologies. The copper (Cu)-based multifunctional polymer-enhanced sensor (CuMPES) represents a notably tailored design for non-invasive environmental monitoring, particularly for detecting diverse gases with a [...] Read more.
Metal-oxide-based gas sensors are extensively utilized across various domains due to their cost-effectiveness, facile fabrication, and compatibility with microelectronic technologies. The copper (Cu)-based multifunctional polymer-enhanced sensor (CuMPES) represents a notably tailored design for non-invasive environmental monitoring, particularly for detecting diverse gases with a low concentration. In this investigation, the Cu-CuO/PEDOT nanocomposite was synthesized via a straightforward chemical oxidation and vapor-phase polymerization. Comprehensive characterizations employing X-ray photoelectron spectroscopy (XPS), scanning electron microscopy (SEM), X-ray diffraction (XRD), and micro Raman elucidated the composition, morphology, and crystal structure of this nanocomposite. Gas-sensing assessments of this CuMPES based on Cu-CuO/PEDOT revealed that the response current of the microneedle-type CuMPES surpassed that of the pure Cu microsensor by nearly threefold. The electrical conductivity and surface reactivity are enhanced by poly (3,4-ethylenedioxythiophene) (PEDOT) polymerized on the CuO-coated surface, resulting in an enhanced sensor performance with an ultra-fast response/recovery of 0.3/0.5 s. Full article
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