Roles of Small RNAs in Virus–Plant Interactions

A special issue of Viruses (ISSN 1999-4915). This special issue belongs to the section "Viruses of Plants, Fungi and Protozoa".

Deadline for manuscript submissions: closed (31 January 2025) | Viewed by 1400

Special Issue Editors


E-Mail Website
Guest Editor
The James Hutton Institute, Invergowrie, Dundee DD2 5DA, UK
Interests: plant–virus interactions; cell nucleus and subnuclear structures; bionanotechnology
Special Issues, Collections and Topics in MDPI journals

E-Mail
Guest Editor
A.N. Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow, Russia
Interests: virus-host interactions; molecular virology; protein expression; RNA

E-Mail Website
Guest Editor
Cell and Molecular Sciences, The James Hutton Institute, Errol Road, Invergowrie, Dundee DD2 5DA, UK
Interests: biotechnology; plant–virus interactions; cell nucleus; defence signalling pathways
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

In recent years, small non-coding RNAs (sncRNAs) have gained unprecedented attention as new and crucial players in the regulation of numerous cellular processes and disease responses. According to their different origins and biogenesis pathways, sncRNAs can be grouped into two major categories: microRNAs (miRNAs) and small interfering RNAs (siRNAs). These two types of sncRNAs share some similarities in size, structure, and functions. Both are key components of the RNA interference, a biological process in which RNA molecules are involved in the sequence-specific suppression of gene expression through translational or transcriptional repression. RNAi is a vital part of the immune response to viruses, especially in plants. The small RNAs produced from double-stranded RNAs (dsRNAs) or hairpin RNAs (hpRNAs), either in transgenic plants or delivered exogenously to non-transgenic plants, may constitute powerful RNAi-based technology that can be exploited to control plant viruses. We welcome papers that present molecular, genetic and biochemical studies elucidating the mechanisms by which small RNAs regulate viral defence in different crops, as well as the distinct pathways of sncRNA biogenesis and the coping strategies used by viruses to override RNAi-based immune response. We also welcome researchers developing new applications in virus defence based on the use of external sncRNAs or their triggers such as dsRNAs or hpRNAs to submit papers to this Special Issue.

Prof. Dr. Michael Taliansky
Prof. Dr. Natalia O. Kalinina
Prof. Dr. Andrew J. Love
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Viruses is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • small non-coding RNAs
  • small interfering RNAs
  • microRNAs
  • RNA interference
  • spray-induced gene silencing
  • host-induced gene silencing
  • plant viruses
  • plant antiviral defence

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.

Further information on MDPI's Special Issue polices can be found here.

Published Papers (1 paper)

Order results
Result details
Select all
Export citation of selected articles as:

Review

27 pages, 1323 KiB  
Review
Exogenous dsRNA-Mediated RNAi: Mechanisms, Applications, Delivery Methods and Challenges in the Induction of Viral Disease Resistance in Plants
by Emmadi Venu, Akurathi Ramya, Pedapudi Lokesh Babu, Bhukya Srinivas, Sathiyaseelan Kumar, Namburi Karunakar Reddy, Yeluru Mohan Babu, Anik Majumdar and Suryakant Manik
Viruses 2025, 17(1), 49; https://doi.org/10.3390/v17010049 - 31 Dec 2024
Viewed by 985
Abstract
The increasing challenges posed by plant viral diseases demand innovative and sustainable management strategies to minimize agricultural losses. Exogenous double-stranded RNA (dsRNA)-mediated RNA interference (RNAi) represents a transformative approach to combat plant viral pathogens without the need for genetic transformation. This review explores [...] Read more.
The increasing challenges posed by plant viral diseases demand innovative and sustainable management strategies to minimize agricultural losses. Exogenous double-stranded RNA (dsRNA)-mediated RNA interference (RNAi) represents a transformative approach to combat plant viral pathogens without the need for genetic transformation. This review explores the mechanisms underlying dsRNA-induced RNAi, highlighting its ability to silence specific viral genes through small interfering RNAs (siRNAs). Key advancements in dsRNA production, including cost-effective microbial synthesis and in vitro methods, are examined alongside delivery techniques such as spray-induced gene silencing (SIGS) and nanocarrier-based systems. Strategies for enhancing dsRNA stability, including the use of nanomaterials like layered double hydroxide nanosheets and carbon dots, are discussed to address environmental degradation challenges. Practical applications of this technology against various plant viruses and its potential to ensure food security are emphasized. The review also delves into regulatory considerations, risk assessments, and the challenges associated with off-target effects and pathogen resistance. By evaluating both opportunities and limitations, this review underscores the role of exogenous dsRNA as a sustainable solution for achieving viral disease resistance in plants. Full article
(This article belongs to the Special Issue Roles of Small RNAs in Virus–Plant Interactions)
Show Figures

Figure 1

Back to TopTop