Enteroviruses: Respiratory and Nervous System Infections
A special issue of Viruses (ISSN 1999-4915). This special issue belongs to the section "Human Virology and Viral Diseases".
Deadline for manuscript submissions: closed (31 January 2025) | Viewed by 1225
Special Issue Editors
Interests: enteroviruses; pathogenesis; rhinovirus; antibodies; neurotropism; neurovirulence; neuroinvasion; viremia; replication; receptors
Special Issue Information
Dear Colleagues,
Enteroviruses are nonenveloped particles, with a single-stranded RNA genome of positive polarity. This virus genus includes over 350 different, including poliovirus, echoviruses, rhinoviruses and Coxsackieviruses. Enteroviruses are common human pathogens, and infection can result in a spectrum of serious illnesses, including acute flaccid myelitis, severe respiratory complications, and hand, foot and mouth disease. Viruses of this genus share significant genetic similarity that can result in cross-reactivity, obscuring the use of serosurveys for surveillance. Despite more than 100 years of studying poliovirus, many unanswered questions remain about the members of this genus, including the cell molecules that mediate virus entry and genome release, replication, mechanisms of intra- and inter-species recombination, virion assembly, the cellular and humoral responses elicited against their infection, durability of the antiviral immune responses, primary sites of infection, mechanisms of dissemination throughout the host and host gene products that modulate disease severity.
Dr. Amy B. Rosenfeld
Prof. Dr. Vincent R. Racaniello
Guest Editors
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Keywords
- enteroviruses
- pathogenesis
- biology
- antibodies
- neurotropism
- neurovirulence
- neuroinvasion
- viremia
- replication
- receptors
- rhinovirus
- innate immunity
- poliovirus
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