Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
7.3
3.8
Journals
Viruses
Special Issues
The 9th Edition of the European Rotavirus Biology Meeting (ERBM-9)
share announcement

The 9th Edition of the European Rotavirus Biology Meeting (ERBM-9)

A special issue of Viruses (ISSN 1999-4915). This special issue belongs to the section "Animal Viruses".

Deadline for manuscript submissions: closed (31 January 2025) | Viewed by 5888

Special Issue Editors

Dr. Javier Buesa

E-Mail Website
Guest Editor
Department of Microbiology, Facultad de Medicina y Odontologia, Universitat de Valencia, Hospital Clinico Universitario de Valencia, Valencia, Spain
Interests: clinical virology; virus-host interactions; enteric viruses: rotaviruses, noroviruses, sapoviruses; pathophysiology of viral gastroenteritis; molecular epidemiology; viral evolution; glycobiology of viruses
Special Issues, Collections and Topics in MDPI journals
Dr. Jesús Rodríguez-Díaz

E-Mail Website
Guest Editor
Department of Microbiology, School of Medicine, University of Valencia, 46010 Valencia, Spain
Interests: molecular epidemiology of rotavirus and norovirus; virus–host interactions; microbiota
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

We are pleased to welcome you to ERBM-9 (the website of the meeting: https://www.erbm-valencia2024.com/ERBM2024), the 9th edition of the European Rotavirus Biology Meeting, in Valencia, Spain. Since 2005, this meeting has provided a forum for the discussion of relevant aspects of rotavirus biology. After a break due to the COVID-19 pandemic, we are happy to announce that the meeting will resume in October 2024.

This two-day meeting will feature scientific sessions with leading experts in rotavirus epidemiology, replication, host genetics, vaccines, and pathophysiology, among others, and will showcase state-of-the-art research from participants with diverse backgrounds, including glycovirology, structural virology, the relationship of rotaviruses with the gut microbiota, and the development of new tools and models to study rotaviruses.

We are particularly excited to hold the meeting live at the Botanic Garden of the University of Valencia in the city of Valencia, Spain, from 2 to 4 October 2024.

Symposium participants, as well as all researchers working in the field, are cordially invited to contribute original research papers or reviews to this Special Issue of Viruses. All participants submitting to this Special Issue will benefit from a 10% discount on the publication fee per article.

Dr. Javier Buesa
Dr. Jesús Rodríguez-Díaz
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Viruses is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • rotaviruses
  • rotavirus vaccines
  • rotavirus epidemiology
  • rotavirus replication
  • host genetics
  • virus–host interactions

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.

Further information on MDPI's Special Issue polices can be found here.

Published Papers (5 papers)

Download All Papers
Order results
Result details
Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:

Research

Jump to: Other

14 pages, 932 KiB  
Article
High Detection Rate of Rotavirus Infection Among Children Admitted with Acute Gastroenteritis to Six Public Hospitals in Luanda Province After the Introduction of Rotarix® Vaccine: A Cross-Sectional Study
by Dikudila Vita, Manuel Lemos, Zoraima Neto, Mathebula Evans, Ngiambudulu M. Francisco, Filomeno Fortes, Ema Fernandes, Celso Cunha and Claudia Istrate
Viruses 2024, 16(12), 1949; https://doi.org/10.3390/v16121949 - 20 Dec 2024
Viewed by 911
Abstract
Rotavirus group A (RVA) is a major cause of pediatric acute gastroenteritis (AGE). Vaccination is an effective public health strategy and Angola implemented it in 2014. This hospital-based study aimed to estimate the prevalence of RVA infection and the severity of AGE in [...] Read more.
Rotavirus group A (RVA) is a major cause of pediatric acute gastroenteritis (AGE). Vaccination is an effective public health strategy and Angola implemented it in 2014. This hospital-based study aimed to estimate the prevalence of RVA infection and the severity of AGE in children under five years of age treated at six hospitals in Luanda Province. Between April 2021 and May 2022, 1251 fecal samples were screened by an immunochromatographic rapid test (SD Bioline). Data on socio-demographic profile, nutritional status, and clinical assessment were obtained. The association of RVA infection and AGE severity with possible risk factors was evaluated with a binary logistic regression model. Overall, the detection rate was 57.8% and girls tend to be more often infected than boys (55.2%). Infection was more common in the youngest group (1 to 6 months, 60.3%). Important sources of RVA infection were drinking water kept in tanks (57.9%) and private sanitary facilities with piped water (61%). Surprisingly, according to the Vesikari Scale score, the most severe symptoms were observed in children vaccinated with two doses (80.7%). RVA prevalence remains high despite vaccination, and further studies should address the association between infection sources and disease severity, as well as the causes underlying vaccine (un)effectiveness. Full article
(This article belongs to the Special Issue The 9th Edition of the European Rotavirus Biology Meeting (ERBM-9))
►▼ Show Figures

Figure 1

12 pages, 748 KiB  
Article
The Apparent Lack of the Risk of Intussusception Immediately After Rotavirus Vaccination Among Japanese Infants
by Wakako Kikuchi, Atsuko Noguchi, Yoko Sato, Yuuki Konno, Akira Komatsu, Satoru Tandai, Wataru Kikuchi, Shinobu Miura, Hiroshi Fukaya, Tomoaki Ohata, Hiroo Noguchi, Kenichi Matsuno, Hisayuki Tsukahara, Daiki Kondo, Masaki Komatsu, Masamichi Tamura, Hiromi Koizumi, Toyoko Nakagomi, Osamu Nakagomi and Tsutomu Takahashi
Viruses 2024, 16(11), 1758; https://doi.org/10.3390/v16111758 - 10 Nov 2024
Viewed by 1121
Abstract
Rotavirus vaccines carry a small risk of intussusception mainly 1–7 days after vaccination in the United States of America, Europe, Australia, and Latin America where the background rate of intussusception is relatively low. Such risks are undetectable in Africa and India where the [...] Read more.
Rotavirus vaccines carry a small risk of intussusception mainly 1–7 days after vaccination in the United States of America, Europe, Australia, and Latin America where the background rate of intussusception is relatively low. Such risks are undetectable in Africa and India where the background rate is the lowest. Because few studies were carried out in high-background-rate countries such as Japan, we examined how intussusception occurred in infants living in Akita prefecture, Japan, while the vaccines were sold in the private market. Between 2011 and 2018, an estimated 21,677 infants (46%) were vaccinated and 54% were not. Through a retrospective survey of medical records in 18 hospitals in the prefecture, we identified 58 infants, 28 of whom were vaccinated and 30 of whom were unvaccinated, as having intussusception that met level 1 of the Brighton criteria. Thus, the intussusception rate was 123 per 100,000 infant-years (95% confidence interval [CI]: 94–160). Despite the high rate, none developed intussusception 1–7 days after the first dose of either the monovalent human rotavirus vaccine (GSK) or the pentavalent human–bovine reassortant vaccine (MSD). The incidence rate ratio of vaccinated to unvaccinated infants between 42 and 245 days of life was estimated at 0.96 (95%CI: 0.43–2.1; p = 0.92). Given that over 95% of infants received the first dose before 15 weeks of age, the risk of intussusception associated with the rotavirus vaccines in high-incidence-rate countries can be reduced to a minimum by adhering to the recommended schedule at 2, 3, and 4 months of age. Full article
(This article belongs to the Special Issue The 9th Edition of the European Rotavirus Biology Meeting (ERBM-9))
►▼ Show Figures

Figure 1

10 pages, 529 KiB  
Communication
Short Communication: Rotavirus Group A Occurrence in Rural Water Source Samples in a Midwest Region State of Brazil, Comparing Wet and Dry Seasons
by Graziela Picciola Bordoni, Lucas Candido Gonçalves Barbosa, Fernando Santos Lima, Mônica de Oliveira Santos, José Daniel Gonçalves Vieira, Thais Reis Oliveira, Paulo Sérgio Scalize and Lilian Carla Carneiro
Viruses 2024, 16(9), 1452; https://doi.org/10.3390/v16091452 - 12 Sep 2024
Viewed by 809
Abstract
Identified as a potential reference pathogen by the WHO Guidelines for Drinking-Water Quality, Rotavirus (RV) is among the main enteric viruses that cause waterborne diseases. The aim of this study was to identify and correlate the presence of RV in collective and individual [...] Read more.
Identified as a potential reference pathogen by the WHO Guidelines for Drinking-Water Quality, Rotavirus (RV) is among the main enteric viruses that cause waterborne diseases. The aim of this study was to identify and correlate the presence of RV in collective and individual water sources of rural communities in the state of Goiás, within the seasons in which the collections were made (rainy and dry seasons). For this, 86 water samples in the dry period and 160 samples in the rainy period were collected. Concentration of water samples, extraction of viral genetic material and molecular tests were performed. When analyzing the presence of RV in the samples, taking into consideration the period studied, RV was found to be more prevalent in the dry season (54.7%) than in the rainy season (20%), showing a strong statistical association with the dry season (p-value < 0.001). The presence of pathogenic microorganisms in water is a public risk issue, enabling the emergence of outbreaks, endemics and epidemics. In the present research, there was an association between the presence of Rotavirus and the dry period of the year when compared to the rainy period. Full article
(This article belongs to the Special Issue The 9th Edition of the European Rotavirus Biology Meeting (ERBM-9))
►▼ Show Figures

Figure 1

15 pages, 2472 KiB  
Article
Updating and Refining of Economic Evaluation of Rotavirus Vaccination in Spain: A Cost–Utility and Budget Impact Analysis
by Iñaki Imaz-Iglesia, Montserrat Carmona, Esther E. García-Carpintero, Lucía Pedrosa-Pérez, Alejandro Martínez-Portillo, Enrique Alcalde-Cabero, Renata Linertová and Lidia García-Pérez
Viruses 2024, 16(8), 1194; https://doi.org/10.3390/v16081194 - 25 Jul 2024
Viewed by 1079
Abstract
Two vaccines against rotavirus diseases, Rotarix® and RotaTeq®, are being marketed in Spain; but rotavirus is not presently among the diseases covered by universal vaccination in Spain. The aim of this study was to assess the efficiency of extending Spain’s [...] Read more.
Two vaccines against rotavirus diseases, Rotarix® and RotaTeq®, are being marketed in Spain; but rotavirus is not presently among the diseases covered by universal vaccination in Spain. The aim of this study was to assess the efficiency of extending Spain’s current targeted rotavirus vaccination strategy including only preterm babies, to a policy of universal vaccination. A de novo cohort-based Markov model was built to evaluate the efficiency of three compared rotavirus vaccination strategies in Spain: targeted, universal, and no vaccination. Using Rotarix® or RotaTeq®, we compared the cost–utility of these strategies from both a societal perspective and Spanish National Health System (SNHS) perspective. The model represents the most important clinical events conceivably linked to rotavirus infection. Efficacy, effectiveness, safety, costs, and utilities were identified by systematic reviews. Incremental cost–utility ratio (ICUR) is EUR 23,638/QALY (Quality-Adjusted Life Year) for targeted vaccination with Rotarix® compared with no vaccination. The ICUR for the rest of the strategies evaluated are above EUR 30,000/QALY. The sensitivity analysis shows price as the only parameter that could make the universal vaccination strategy efficient. Considering a threshold of EUR 25,000/QALY, only targeted vaccination with Rotarix® would be efficient from societal perspective. Price drops of 36.9% for Rotarix® and 44.6% for RotaTeq® would make universal vaccination efficient. Full article
(This article belongs to the Special Issue The 9th Edition of the European Rotavirus Biology Meeting (ERBM-9))
►▼ Show Figures

Figure 1

Other

Jump to: Research

6 pages, 1697 KiB  
Brief Report
Whole Genome Sequences of the Wildtype AU-1 Rotavirus A Strain: The Prototype of the AU-1-like Genotype Constellation
by Chantal Ama Agbemabiese, Francis Ekow Dennis, Belinda Larteley Lartey, Susan Afua Damanka, Toyoko Nakagomi, Osamu Nakagomi and George Enyimah Armah
Viruses 2024, 16(10), 1529; https://doi.org/10.3390/v16101529 - 27 Sep 2024
Viewed by 775
Abstract
Most human rotaviruses belong to the Wa-like, DS-1-like, or AU-1-like genotype constellation. The AU-1-like constellation, albeit minor, captured attention because its prototype strain AU-1 originated from feline rotavirus, leading to the concept of interspecies transmission of rotavirus. The AU-1 genome sequence determined by [...] Read more.
Most human rotaviruses belong to the Wa-like, DS-1-like, or AU-1-like genotype constellation. The AU-1-like constellation, albeit minor, captured attention because its prototype strain AU-1 originated from feline rotavirus, leading to the concept of interspecies transmission of rotavirus. The AU-1 genome sequence determined by various laboratories over the years has documented two conflicting VP7 sequences in the GenBank. As culture-adaptation may introduce changes in the viral genome, the original fecal (wild-type) and the seed stock of culture-adapted AU-1 genomes were sequenced using the Illumina’s MiSeq platform to determine the authentic AU-1 sequence and to identify what mutational changes were selected during cell-culture adaptation. The wild-type and culture-adapted AU-1 genomes were identical except for one VP4-P475L substitution. Their VP7 gene was 99.9% identical to the previously reported AU-1 VP7 under accession number AB792641 but only 92.5% to that under accession number D86271. Thus, the wild-type sequences determined in this study (accession numbers OR727616-OR727626) should be used as the reference. The VP4-P475L mutation was more likely incidental than inevitable during cell-culture adaptation. This was the first study in which the whole genomes of both wild-type and cultured RVA strains were simultaneously determined by deep sequencing. Full article
(This article belongs to the Special Issue The 9th Edition of the European Rotavirus Biology Meeting (ERBM-9))
►▼ Show Figures

Figure 1

Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:
 
Displaying articles 1-5
Back to TopTop