Advances in Rabies Research 2024

A special issue of Viruses (ISSN 1999-4915). This special issue belongs to the section "General Virology".

Deadline for manuscript submissions: 1 April 2025 | Viewed by 3017

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Guest Editor
Centro Nacional de Servicios de Diagnóstico en Salud Animal, Tecámac, Mexico
Interests: molecular virology; cell culture; immunology of infectious diseases; virus diseases; immunization; diagnostics; emerging infectious diseases; infectious disease control and prevention; vaccines; veterinary diagnostics
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Special Issue Information

Dear Colleagues,

The aim of this Special Issue, entitled “Advances in Rabies Research 2024”, is to continue to collect novel contributions in the field of rabies research, providing new insights and addressing research on unresolved issues. Evolution, structural biology, viral replication, virus–host interaction, pathogenesis and immunity, clinical virology of medical and veterinarian relevance, gene therapy, and novel antiviral strategies are a selection of topics relevant to research in the field, and manuscripts on these topics can be submitted to this Special Issue.

The Special Issue is associated with the following two Rabies In The Americas (RITA) international conferences: RITA XXXIV, which took place in Bogota, Colombia, in October 2023, and RITA XXXV, which will now be taking place in Buenos Aires, Argentina, from 3 to 8 November 2024. RITA is a conference that has been held every year since 1990 by the United States of America, Canada, and Mexico, and more recently by Brazil and Argentina, as well as other Latin American countries; it aims to connect researchers, national and local directors of programs, laboratory workers and all those in the Americas and in other parts of the world who are involved in the surveillance, prevention and control of rabies. RITA conferences are events strictly centered on all aspects of rabies research and provide excellent opportunities to focus on research topics in this area. Symposium participants are cordially invited to contribute their original research papers presented at these two RITA conferences to this Special Issue of Viruses. For further information, please visit the following website: Rita 2024—Rabies In The Americas 2024 (ritaconference.org).

Prof. Dr. Charles E. Rupprecht
Dr. Juan A. Montaño-Hirose
Guest Editors

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Keywords

  • rabies
  • zoonosis
  • vaccine
  • evolution
  • structural biology
  • viral replication
  • virus–host interaction
  • pathogenesis and immunity
  • clinical virology

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Published Papers (1 paper)

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Review

18 pages, 870 KiB  
Review
Rabies in Cats—An Emerging Public Health Issue
by Christine Fehlner-Gardiner, Gyanendra Gongal, Tenzin Tenzin, Claude Sabeta, Paola De Benedictis, Silene Manrique Rocha, Alexander Vargas, Natalia Cediel-Becerra, Luis Carlos Gomez, Joanne Maki and Charles E. Rupprecht
Viruses 2024, 16(10), 1635; https://doi.org/10.3390/v16101635 - 19 Oct 2024
Viewed by 2473
Abstract
Human rabies cases today are predominantly associated with infection from rabid domestic dogs. Unlike dogs, a common global reservoir species that perpetuates rabies viruses (RABV) within their populations, domestic cats are much less frequently reported or vaccinated. Epidemiologically, cats are important vectors of [...] Read more.
Human rabies cases today are predominantly associated with infection from rabid domestic dogs. Unlike dogs, a common global reservoir species that perpetuates rabies viruses (RABV) within their populations, domestic cats are much less frequently reported or vaccinated. Epidemiologically, cats are important vectors of lyssaviruses but are not viral reservoirs. Typically, cats are incidental hosts only, infected with the predominant lyssavirus in their geographic locale. Human cases associated with rabid cats have occurred in Africa, Asia, Europe and throughout the Americas. As adept, solitary hunters, wild and domestic felids are at risk of lyssavirus infection based upon interactions with infected prey, such as bats, or from transmission by other mesocarnivores, such as rabid dogs, foxes, jackals, raccoons, and skunks. Current veterinary vaccines provide safe and effective immunity in cats against phylogroup I lyssaviruses, such as RABV, but not against divergent lyssaviruses in phylogroups II-IV. With the focus upon the global elimination of canine rabies, the emergence of rabies in cats represents a concerning trend. Clearly, education about the occurrence of rabies in cats needs to be improved, as well as the routine vaccination of cats to reduce the associated risks to public health, agriculture, and conservation biology from a One Health perspective. Full article
(This article belongs to the Special Issue Advances in Rabies Research 2024)
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