Mechanical Study of Biomaterials in Injury and Rehabilitation

Topic Information

Dear Colleagues,

Current research in the field of mechanical study of biomaterials for injury and rehabilitation is focused on developing strategies to enhance tissue regeneration and improve the mechanical properties of implants. Biomimetic approaches are being used to create materials that mimic the structure and function of natural tissues. Mechanical loading is being explored to stimulate tissue growth, and advanced imaging techniques are being used to better understand the mechanical properties of tissues and biomaterials. Researchers are also investigating the use of 3D printing technology to create custom implants with tailored mechanical properties. However, various challenges remain, including developing materials that are both biocompatible and have the desired mechanical properties, as well as understanding the biological responses to different mechanical stimuli. The goal of this research is to improve patient outcomes by developing biomaterials that can better support tissue healing and improve the mechanical properties of medical devices.

This Topic is focused on the mechanical study of biomaterials in injury and rehabilitation, exploring their potential applications in treating injuries and aiding in rehabilitation. Submissions are encouraged, but not limited to, the following general areas:

• Biomaterials in bone regeneration;
• Mechanical properties of implantable materials for tendon and ligament tissues;
• Design of implantable devices;
• Biomechanics;
• New models of the damage mechanics of composite structures and human tissue.

This Topic will bring together recent research in an effort to identify new opportunities and further develop this field.

Prof. Dr. Lizhen Wang
Prof. Dr. Bo Huo
Dr. Wenming Chen
Dr. Dohyung Lim
Topic Editors

Keywords

Participating Journals

Journal Name	Impact Factor	CiteScore	Launched Year	First Decision (median)	APC
Journal of Functional Biomaterials jfb	5.0	4.6	2010	15.8 Days	CHF 2700	Submit
Materials materials	3.1	5.8	2008	15.5 Days	CHF 2600	Submit

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15 pages, 11412 KiB  

Open AccessArticle

Investigation of the Friction Properties of a New Artificial Imitation Cartilage Material: PHEMA/Glycerol Gel

by Zikai Hua, Mindie Hu, Yiwen Chen, Xiuling Huang and Leiming Gao

Materials 2023, 16(11), 4023; https://doi.org/10.3390/ma16114023 - 28 May 2023

Cited by 2 | Viewed by 1558

Abstract

The absence of artificial articular cartilage could cause the failure of artificial joints due to excessive material wear. There has been limited research on alternative materials for articular cartilage in joint prostheses, with few reducing the friction coefficient of artificial cartilage prostheses to [...] Read more.

The absence of artificial articular cartilage could cause the failure of artificial joints due to excessive material wear. There has been limited research on alternative materials for articular cartilage in joint prostheses, with few reducing the friction coefficient of artificial cartilage prostheses to the range of the natural cartilage friction coefficient (0.001–0.03). This work aimed to obtain and characterize mechanically and tribologically a new gel for potential application in articular replacement. Therefore, poly(hydroxyethyl methacrylate) (PHEMA)/glycerol synthetic gel was developed as a new type of artificial joint cartilage with a low friction coefficient, especially in calf serum. This glycerol material was developed via mixing HEMA and glycerin at a mass ratio of 1:1. The mechanical properties were studied, and it was found that the hardness of the synthetic gel was close to that of natural cartilage. The tribological performance of the synthetic gel was investigated using a reciprocating ball-on-plate rig. The ball samples were made of a cobalt-chromium-molybdenum (Co-Cr-Mo) alloy, and the plates were synthetic glycerol gel and two additional materials for comparison, which were ultra-high molecular polyethylene (UHMWPE) and 316L stainless steel. It was found that synthetic gel exhibited the lowest friction coefficient in both calf serum (0.018) and deionized water (0.039) compared to the other two conventional materials for knee prostheses. The surface roughness of the gel was found to be 4–5 μm through morphological analysis of wear. This newly proposed material provided a possible solution as a type of cartilage composite coating with hardness and tribological performance close to the nature of use in wear couples with artificial joints. Full article

(This article belongs to the Topic Mechanical Study of Biomaterials in Injury and Rehabilitation)
(This article belongs to the Section Biomaterials)

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