Oxidative Stress in Red Blood Cells
A special issue of Antioxidants (ISSN 2076-3921). This special issue belongs to the section "Health Outcomes of Antioxidants and Oxidative Stress".
Deadline for manuscript submissions: 20 April 2025 | Viewed by 491
Special Issue Editors
Interests: oxidative stress events; glycation; aging; membrane transport systems
Special Issues, Collections and Topics in MDPI journals
Interests: human physiology; cell physiology; membrane transport systems; bioactive compound; oxidative stress; human health
Special Issues, Collections and Topics in MDPI journals
Interests: oxidative stress events; glycation; aging; membrane transport systems
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Red blood cells (RBCs) are unique and highly specialized cells. Being involved in respiratory gas transportation and highly susceptible to oxidative damage, they are equipped with effective anti-oxidative systems providing them with antioxidant protection, along with protection for body tissues and organs. When oxidants are produced in excess or when the antioxidant defences are ineffective, the resulting oxidative condition, which in some cases is useful for cell growth and signaling, causes both biochemical and biophysical deleterious effects, e.g., disruption in the bilayer molecular arrangement, changes in morphology and mechanics, thus compromising RBC homeostasis, which may correlate with the development of oxidative-stress-related diseases.
This Special Issue will focus on the molecular mechanisms underlying the cell redox endogenous system and oxidative stress (OS) in RBCs, with specific regard to the OS impact on cellular components, including membrane ion transport systems. The aim is also to provide more information about cell response to OS in human pathologic conditions, mainly in those displaying systemic OS as a hallmark, and its possible modulation by novel antioxidant strategies. In this regard, molecular targets at the level of the cellular membrane and their potential modulation under OS will be also considered. The beneficial effects of antioxidants and possible cell adaptation mechanisms to OS will be worthy of note. Studies using animal or cell models, as well as clinical studies are welcome.
The Special Issue welcomes high-quality research articles and review articles focusing on the relationship between OS and RBC responses.
Dr. Angela Marino
Dr. Rossana Morabito
Dr. Alessia Remigante
Guest Editors
Manuscript Submission Information
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Keywords
- erythropoiesis
- membrane transports
- biophysical and biochemical RBC properties
- blood bank storage
- adaptations to stress
- the use of RBCs as drug carriers or biomarkers
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