CRISPR-Based Biosensing for Point-of-Care Diagnostics

A special issue of Biosensors (ISSN 2079-6374). This special issue belongs to the section "Biosensor and Bioelectronic Devices".

Deadline for manuscript submissions: 30 June 2025 | Viewed by 9

Special Issue Editors


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Guest Editor
College of Control Science and Engineering, Zhejiang University, Hangzhou 310007, China
Interests: microfluidics system and its application in life sciences; surface plasmon resonance biosensors; integrated nanobiotechnology
Special Issues, Collections and Topics in MDPI journals
Department of Nutrition and Food Hygiene, School of Public Health, Southeast University, Nanjing 210009, China
Interests: enzyme engineering and synthetic biology for molecular diagnostics; isothermal nucleic acid amplification and biosensors; rapid detection systems and all-in-one microfluidic diagnostics
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Department of Nutrition and Food Hygiene, School of Public Health, Southeast University, Nanjing 210009, China
Interests: microfluidic device for health care; rapid antimicrobial susceptibility testing; single-molecule detection technology; high-sensitive optical biosensor

Special Issue Information

Dear Colleagues,

Point-of-care (POC) diagnostics are essential for the timely and efficient prevention, control, and treatment of human diseases, including cancers, infections, and even epidemic outbreaks. POC diagnostics based on the detection of pathogenic nucleic acids, antibodies, antigens, and small molecules are advantageous over other strategies due to their high detection sensitivity and specificity. Currently, clustered regularly interspaced short palindromic repeats (CRISPR)-leveraged biosensing has emerged as an innovative strategy, enabling rapid and accurate POC testing. The CRISPR-based diagnostic toolbox has expanded rapidly, involving CRISPR-coupled polymerase chain reaction, isothermal amplification, electrochemical analysis, diagnostic materials/nanomaterials, microfluidic analysis, and chemiluminescence/lateral flow immunoassays. This surge in development brings substantial promise for the industrialization of CRISPR-based diagnostic products in the near future.

We are pleased to invite you to submit your manuscripts to our Special Issue titled “CRISPR-Based Biosensing for Point-of-Care Diagnostics”. This Special Issue aims to summarize the state-of-the-art detection strategies, improved reagents/materials, and emerging applications of CRISPR-based biosensing for disease-associated targets, including pathogenic nucleic acids, antibodies, antigens, and small molecules. We are confident that this Special Issue will engage readers and inspire new contributions to the field of CRISPR-based biosensing. We welcome original research articles and reviews in research areas such as biomedical engineering, biosensing/biosensors, molecular biology, biochemistry, nanomaterials, microfluidics, diagnostics, and theranostics.

We look forward to receiving your contributions.

Prof. Dr. Ying Mu
Dr. Xiong Ding
Dr. Wenshuai Wu
Guest Editors

Manuscript Submission Information

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Keywords

  • point-of-care diagnostics
  • nucleic acid detection
  • polymerase chain reaction
  • isothermal amplification
  • electrochemical analysis
  • diagnostic materials
  • diagnostic nanomaterials
  • microfluidic analysis
  • chemiluminescence immunoassays
  • lateral flow immunoassays

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Published Papers

This special issue is now open for submission.
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