Biomedical Ceramics and Glasses

A special issue of Ceramics (ISSN 2571-6131).

Deadline for manuscript submissions: closed (30 June 2021) | Viewed by 20027

Special Issue Editors


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Institute of Materials Physics and Engineering, Department of Applied Science and Technology, Politecnico di Torino, Corso Duca degli Abruzzi 24, 10129 Turin, Italy
Interests: ceramics; glasses; porous materials; additive manufacturing; bioactive glasses; bioceramics; composites; tissue engineering; multifunctional biomaterials; biomedical scaffolds; advanced ceramics; sustainable materials; waste management
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Guest Editor
Materials Science Department, MATEIS, University of Lyon, INSA-LYON, UMR CNRS, 5510 Lyon, France
Interests: biomaterials; ceramics; mechanics of materials
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Guest Editor
Materials: Engineering and Science Laboratory, Univ-Lyon, INSA Lyon, CNRS, France
Interests: biomaterials; ceramics
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Guest Editor
Mechanical Engineering Department, Federal University of Santa Catarina, Florianópolis 88040-900, SC, Brazil
Interests: bioceramics; dental ceramics; laser structuring; zirconia; bioactive glasses; calcium phosphates; additive manufacturing; tissue engineering
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The unique properties of some “special” ceramics have resulted in their widespread use as medical implant materials in an expanding range of forms and applications over the last 50 years. Biocompatible ceramics, commonly called “bioceramics”, can be used for structural and/or regenerative purposes with a significant clinical impact. Strong bioceramics, such as alumina, zirconia and their composites, as well as more recently silicon nitride, have been recognized as suitable materials to fabricate load-bearing prosthetic joint surfaces due to their excellent wear and mechanical properties. Hydroxyapatite, resorbable calcium phosphates and bioactive glasses/glass-ceramics are used to regenerate bone in orthopaedic and dental applications, and some special glass formulations have also been found to be able to interact with soft tissues, thereby opening up new horizons in the field of tissue engineering and drug delivery. Nano-sized ceramics, such as magnetite nanoparticles and nanoceria, show great promise for the targeted therapy of cancer and other diseases.

Furthermore, the recent advent of new manufacturing technologies, such as additive manufacturing (often known as 3D printing) and biofabrication, has allowed researchers to achieve new impressive advancement in the processing of bioceramics to impart new extra-functionalities and properties to them.

This Special Issue covers all the key areas related to the concept, design, fabrication, characterization, modelling, clinical use and commercialization of bioceramics and related composites or combinations. Full research articles, short communications and comprehensive reviews dealing with topics are welcome. 

Dr. Francesco Baino
Prof. Jérôme Chevalier
Dr. Laurent Gremillard
Prof. Dr. Bruno Alexandre P. C. Henriques
Guest Editors

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Keywords

  • Bioactive ceramics and glasses
  • Load-bearing bioceramics
  • Coatings
  • Scaffolds
  • Surface functionalization
  • Composites and hybrids
  • Nanoceramics and mesoporous ceramics
  • Additive manufacturing
  • Biofabrication
  • Bone repair and regeneration
  • Dental ceramics
  • Tissue engineering
  • Drug delivery

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Published Papers (2 papers)

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Research

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13 pages, 6068 KiB  
Article
Mechanical Properties of 2Y-TZP Fabricated from Detonation Synthesized Powder
by Frank Kern and Andrea Gommeringer
Ceramics 2020, 3(4), 440-452; https://doi.org/10.3390/ceramics3040037 - 2 Nov 2020
Cited by 10 | Viewed by 3571
Abstract
Yttria stabilized zirconia (Y-TZP) is frequently used in dental and engineering applications due to its high strength and fracture resistance. In this study, 2Y-TZP samples were manufactured from commercially available powder produced by detonation synthesis. Tests of the mechanical properties exhibited an unusual [...] Read more.
Yttria stabilized zirconia (Y-TZP) is frequently used in dental and engineering applications due to its high strength and fracture resistance. In this study, 2Y-TZP samples were manufactured from commercially available powder produced by detonation synthesis. Tests of the mechanical properties exhibited an unusual combination of both very high strength and toughness. The materials show a very weak correlation between toughness and grain size. The transformability, measurable by XRD, cannot explain the high toughness. Fractographic analysis revealed a broad transformation affected zone with secondary cracks and shear bands on the tensile side of bending bars which can be made responsible for the high toughness and non-linear stress–strain curves. Full article
(This article belongs to the Special Issue Biomedical Ceramics and Glasses)
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Review

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22 pages, 2449 KiB  
Review
Hydroxyapatite for Biomedical Applications: A Short Overview
by Elisa Fiume, Giulia Magnaterra, Abbas Rahdar, Enrica Verné and Francesco Baino
Ceramics 2021, 4(4), 542-563; https://doi.org/10.3390/ceramics4040039 - 28 Sep 2021
Cited by 148 | Viewed by 15031
Abstract
Calcium phosphates (CaPs) are biocompatible and biodegradable materials showing a great promise in bone regeneration as good alternative to the use of auto- and allografts to guide and support tissue regeneration in critically-sized bone defects. This can be certainly attributed to their similarity [...] Read more.
Calcium phosphates (CaPs) are biocompatible and biodegradable materials showing a great promise in bone regeneration as good alternative to the use of auto- and allografts to guide and support tissue regeneration in critically-sized bone defects. This can be certainly attributed to their similarity to the mineral phase of natural bone. Among CaPs, hydroxyapatite (HA) deserves a special attention as it, actually is the main inorganic component of bone tissue. This review offers a comprehensive overview of past and current trends in the use of HA as grafting material, with a focus on manufacturing strategies and their effect on the mechanical properties of the final products. Recent advances in materials processing allowed the production of HA-based grafts in different forms, thus meeting the requirements for a range of clinical applications and achieving enthusiastic results both in vitro and in vivo. Furthermore, the growing interest in the optimization of three-dimensional (3D) porous grafts, mimicking the trabecular architecture of human bone, has opened up new challenges in the development of bone-like scaffolds showing suitable mechanical performances for potential use in load bearing anatomical sites. Full article
(This article belongs to the Special Issue Biomedical Ceramics and Glasses)
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