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Diagnostics
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Clinical Relevance and Usefulness of Strain Imaging
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Clinical Relevance and Usefulness of Strain Imaging

A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Medical Imaging and Theranostics".

Deadline for manuscript submissions: closed (30 November 2021) | Viewed by 16811

Special Issue Editor

Dr. Daniel A. Morris

E-Mail Website
Guest Editor
Department of Internal Medicine and Cardiology, Charité-Universitätsmedizin Berlin, Campus Virchow Klinikum, Augustenburger Platz 1, 13353 Berlin, Germany
Interests: HFpEF (heart failure with preserved ejection fraction); diastolic dysfunction; echocardiography; speckle-tracking echocardiography; strain; LV strain; LA strain; RV strain; aortic stenosis
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The journal Diagnostics (a PubMed indexed Journal; IF 3.1) is planning a Special Issue entitled “Clinical Relevance and Usefulness of Strain Imaging”, which will highlight the potential usefulness and clinical relevance of strain imaging in cardiovascular diseases. Specifically, this Special Issue will address the clinical, prognostic, or diagnostic relevance of new imaging parameters such as left atrial strain, right ventricular strain, left ventricular strain, left ventricular diastolic strain rate, myocardial work index, mechanical dispersion, or new proposed strain indices or algorithms using speckle-tracking echocardiography or magnetic resonance in patients with diverse cardiovascular diseases.

We are looking forward to receiving your contribution as an original research article, a review, a meta-analysis article, a systematic review, a clinical trial article, or a study design article.

Yours sincerely,
Dr. Daniel A. Morris
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Diagnostics is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Strain imaging
  • Cardiovascular Magnetic Resonance
  • Echocardiography

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Published Papers (5 papers)

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Research

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14 pages, 638 KiB  
Article
Feasibility, Reproducibility and Reference Ranges of Left Atrial Strain in Preterm and Term Neonates in the First 48 h of Life
by Benjamim Ficial, Iuri Corsini, Maria Clemente, Alessia Cappelleri, Giulia Remaschi, Laura Quer, Giulia Urbani, Camilla Sandrini, Paolo Biban, Carlo Dani and Giovanni Benfari
Diagnostics 2022, 12(2), 350; https://doi.org/10.3390/diagnostics12020350 - 29 Jan 2022
Cited by 6 | Viewed by 2878
Abstract
Left atrial strain (LAS) is the most promising technique for assessment of diastolic dysfunction but few data are available in neonates. Our aim was to assess feasibility and reproducibility, and to provide reference ranges of LAS in healthy neonates in the first 48 [...] Read more.
Left atrial strain (LAS) is the most promising technique for assessment of diastolic dysfunction but few data are available in neonates. Our aim was to assess feasibility and reproducibility, and to provide reference ranges of LAS in healthy neonates in the first 48 h of life. We performed one echocardiography in 30 neonates to assess feasibility and develop a standard protocol for image acquisition and analysis. LAS reservoir (LASr), conduit (LAScd) and contraction (LASct) were measured. We performed echocardiography at 24 and 48 h of life in an unrelated cohort of 90 neonates. Median (range) gestational age and weight of the first cohort were 34.4 (26.4–40.2) weeks and 2075 (660–3680) g. LAS feasibility was 96.7%. Mean (SD) gestational age and weight of the second cohort were 34.2 (3.8) weeks and 2162 (833) g. Mean (SD) LASr significantly increased from 24 to 48 h: 32.9 (3.2) to 36.8 (4.6). Mean (SD) LAScd and LASct were stable: −20.6 (8.0) and −20.8 (9.9), −11.6 (4.9) and −13.5 (6.4). Intra and interobserver intraclass correlation coefficient for LASr, LAScd and LASct were 0.992, 0.993, 0.986 and 0.936, 0.938 and 0.871, respectively. We showed high feasibility and reproducibility of LAS in neonates and provided reference ranges. Full article
(This article belongs to the Special Issue Clinical Relevance and Usefulness of Strain Imaging)
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Review

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19 pages, 4445 KiB  
Review
Strain Imaging for the Early Detection of Cardiac Remodeling and Dysfunction in Primary Aldosteronism
by Yilin Chen, Tingyan Xu, Jianzhong Xu, Limin Zhu, Dian Wang, Yan Li and Jiguang Wang
Diagnostics 2022, 12(2), 543; https://doi.org/10.3390/diagnostics12020543 - 20 Feb 2022
Cited by 5 | Viewed by 2330
Abstract
Speckle tracking echocardiography is a novel technique to quantify cardiac function and deformation. It has been applied in a series of cardiovascular diseases for the evaluation of early cardiac impairment. We recently used this technique to investigate cardiac structure and function in patients [...] Read more.
Speckle tracking echocardiography is a novel technique to quantify cardiac function and deformation. It has been applied in a series of cardiovascular diseases for the evaluation of early cardiac impairment. We recently used this technique to investigate cardiac structure and function in patients with primary aldosteronism. Cardiac damage usually occurs earlier in patients with primary aldosteronism than those with primary hypertension, probably because aldosterone hypersecretion is more commonly observed in the former than the latter patients. In this article, we will review the imaging studies, especially with speckle tracking echocardiography, for the detection of early cardiac dysfunction in primary aldosteronism as a disease model. Full article
(This article belongs to the Special Issue Clinical Relevance and Usefulness of Strain Imaging)
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22 pages, 2428 KiB  
Review
Right Ventricular Longitudinal Strain in Patients with Heart Failure
by Mengmeng Ji, Wenqian Wu, Lin He, Lang Gao, Yanting Zhang, Yixia Lin, Mingzhu Qian, Jing Wang, Li Zhang, Mingxing Xie and Yuman Li
Diagnostics 2022, 12(2), 445; https://doi.org/10.3390/diagnostics12020445 - 9 Feb 2022
Cited by 16 | Viewed by 4465
Abstract
Patients with heart failure (HF) have high morbidity and mortality. Accurate assessment of right ventricular (RV) function has important prognostic significance in patients with HF. However, conventional echocardiographic parameters of RV function have limitations in RV assessments due to the complex geometry of [...] Read more.
Patients with heart failure (HF) have high morbidity and mortality. Accurate assessment of right ventricular (RV) function has important prognostic significance in patients with HF. However, conventional echocardiographic parameters of RV function have limitations in RV assessments due to the complex geometry of right ventricle. In recent years, speckle tracking echocardiography (STE) has been developed as promising imaging technique to accurately evaluate RV function. RV longitudinal strain (RVLS) using STE, as a sensitive index for RV function evaluation, displays the powerfully prognostic value in patients with HF. Therefore, the aim of the present review was to summarize the utility of RVLS in patients with HF. Full article
(This article belongs to the Special Issue Clinical Relevance and Usefulness of Strain Imaging)
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12 pages, 3995 KiB  
Review
Myocardial Postsystolic Shortening and Early Systolic Lengthening: Current Status and Future Directions
by Philip Brainin
Diagnostics 2021, 11(8), 1428; https://doi.org/10.3390/diagnostics11081428 - 6 Aug 2021
Cited by 17 | Viewed by 2727
Abstract
The concept of paradoxical myocardial deformation, commonly referred to as postsystolic shortening and early systolic lengthening, was originally described in the 1970s when assessed by invasive cardiac methods, such as ventriculograms, in patients with ischemia and animal experimental models. Today, novel tissue-based imaging [...] Read more.
The concept of paradoxical myocardial deformation, commonly referred to as postsystolic shortening and early systolic lengthening, was originally described in the 1970s when assessed by invasive cardiac methods, such as ventriculograms, in patients with ischemia and animal experimental models. Today, novel tissue-based imaging technology has revealed that these phenomena occur far more frequently than first described. This article defines these deformational patterns, summarizes current knowledge about their existence and highlights the clinical potential associated with their understanding. Full article
(This article belongs to the Special Issue Clinical Relevance and Usefulness of Strain Imaging)
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18 pages, 1214 KiB  
Review
The Prognostic Importance of Right Ventricular Longitudinal Strain in Patients with Cardiomyopathies, Connective Tissue Diseases, Coronary Artery Disease, and Congenital Heart Diseases
by Marijana Tadic, Johannes Kersten, Nicoleta Nita, Leonhard Schneider, Dominik Buckert, Birgid Gonska, Dominik Scharnbeck, Tilman Dahme, Armin Imhof, Evgeny Belyavskiy, Cesare Cuspidi and Wolfgang Rottbauer
Diagnostics 2021, 11(6), 954; https://doi.org/10.3390/diagnostics11060954 - 26 May 2021
Cited by 17 | Viewed by 3434
Abstract
Right ventricular (RV) systolic function represents an important independent predictor of adverse outcomes in many cardiovascular (CV) diseases. However, conventional parameters of RV systolic function (tricuspid annular plane excursion (TAPSE), RV myocardial performance index (MPI), and fractional area change (FAC)) are not always [...] Read more.
Right ventricular (RV) systolic function represents an important independent predictor of adverse outcomes in many cardiovascular (CV) diseases. However, conventional parameters of RV systolic function (tricuspid annular plane excursion (TAPSE), RV myocardial performance index (MPI), and fractional area change (FAC)) are not always able to detect subtle changes in RV function. New evidence indicates a significantly higher predictive value of RV longitudinal strain (LS) over conventional parameters. RVLS showed higher sensitivity and specificity in the detection of RV dysfunction in the absence of RV dilatation, apparent wall motion abnormalities, and reduced global RV systolic function. Additionally, RVLS represents a significant and independent predictor of adverse outcomes in patients with dilated cardiomyopathy (CMP), hypertrophic CMP, arrhythmogenic RV CMP, and amyloidosis, but also in patients with connective tissue diseases and patients with coronary artery disease. Due to its availability, echocardiography remains the main imaging tool for RVLS assessment, but cardiac magnetic resonance (CMR) also represents an important additional imaging tool in RVLG assessment. The findings from the large studies support the routine evaluation of RVLS in the majority of CV patients, but this has still not been adopted in daily clinical practice. This clinical review aims to summarize the significance and predictive value of RVLS in patients with different types of cardiomyopathies, tissue connective diseases, and coronary artery disease. Full article
(This article belongs to the Special Issue Clinical Relevance and Usefulness of Strain Imaging)
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