Bioactive Ingredients in Functional Foods—Their Role in Lipid Metabolism

A special issue of Foods (ISSN 2304-8158). This special issue belongs to the section "Food Nutrition".

Deadline for manuscript submissions: 31 January 2025 | Viewed by 598

Special Issue Editors


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Guest Editor
Laboratório de Nutrição Experimental (LANEX), Departamento de Nutrição (DEPNUT), Universidade Federal da Paraíba UFPB, João Pessoa, Brazil
Interests: animal models; anti-inflammatory markers; antioxidants; bioactive compounds; byproducts; dyslipidemia; diabetes; gut–brain axis; gut–liver axis; obesity; non-conventional food plants; plant-based products; phytochemicals

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Guest Editor Assistant
Instituto Nacional do Semiárido (INSA), Ministério da Ciência Tecnologia e Inovação, Campina Grande, Brazil
Interests: anti-inflammatory; antioxidants; bioactive compounds; byproducts; dyslipidemia; chronic diseases; functional foods; gut modulation; nutraceutical potential

Special Issue Information

Dear Colleagues,

Lipid metabolism, a complex process crucial for maintaining physiological balance, has garnered significant attention due to its implications for health and disease. In parallel, functional foods, rich in bioactive compounds, have emerged as promising tools for influencing lipid metabolism and addressing associated disorders such as dyslipidemia, obesity, and cardiovascular diseases. However, comprehensive understanding is still lacking regarding the mechanisms through which these compounds exert their effects and their impact on the absorption, synthesis, transport, excretion, and oxidation of lipids in the body. Therefore, this Special Issue aims to explore the potential of functional foods, abundant in bioactives, to prevent and treat disorders related to lipid metabolism, encompassing both preventive and therapeutic approaches.

We welcome original articles or reviews addressing, but not limited to, the following topics:

  • The influence of bioactive compounds (e.g., phenolics, omega-3 fatty acids, prebiotic fibers, phytosterols) on lipid metabolism pathways;
  • The identification and characterization of bioactive compounds with properties for modulating lipids in cell models, pre-clinical, and clinical studies;
  • The molecular mechanisms of action of bioactive compounds and assessment of their bioavailability and effectiveness;
  • Investigation of synergistic interactions among bioactive ingredients and assessment of their impact on lipid metabolism in cell models, pre-clinical, and clinical studies.

Prof. Dr. Jailane De Souza Aquino
Guest Editor

Dr. Kamila Sabino Batista
Guest Editor Assistant

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Keywords

  • antioxidants
  • lipid profile management
  • lipid metabolism enzymes
  • cholesterol and fatty acid metabolism
  • dyslipidemia and cardiovascular diseases
  • plant-based foods
  • obesity
  • animal models
  • clinical studies
  • cell lines

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Published Papers (1 paper)

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Research

19 pages, 8014 KiB  
Article
Hepatoprotective, Lipid-Lowering and Antioxidant Effects of Mangaba Powder (Hancornia speciosa) Administered to Rats Fed a High-Fat Diet
by Bernadete de Lourdes de Araújo Silva, Margarida Angélica da Silva Vasconcelos, Kamila Sabino Batista, Fabiane Rabelo da Costa Batista, Hassler Clementino Cavalcante, Lydiane de Lima Tavares Toscano, Alexandre Sérgio Silva, Aline Barbosa D’Oliveira, Adriano Francisco Alves and Jailane de Souza Aquino
Foods 2024, 13(23), 3773; https://doi.org/10.3390/foods13233773 - 25 Nov 2024
Viewed by 284
Abstract
The aim of this study was to evaluate the potential effects of administering mangaba powder on liver function and somatic, oxidative and lipid metabolism parameters in rats fed a high-fat diet. Prepared mangaba powder has important amounts of phenolic compounds, vitamin C, dietary [...] Read more.
The aim of this study was to evaluate the potential effects of administering mangaba powder on liver function and somatic, oxidative and lipid metabolism parameters in rats fed a high-fat diet. Prepared mangaba powder has important amounts of phenolic compounds, vitamin C, dietary fiber and oligosaccharides. A total of 32 adult Wistar rats were initially randomized into two groups for the biological assay: normal-fat (NF, n = 16) and high-fat (HF, n = 16) diets for 21 days. These rats were subsequently subdivided into four groups: NF (n = 8), HF (n = 8), normal-fat diet with mangaba powder administration (NFMG, n = 8) and high-fat diet with mangaba powder administration (HFMG, n = 8). The treatment with mangaba powder (400 mg/kg) lasted an additional 28 days. Compared to the HF rats, the HFMG rats showed an 8% reduction in the body mass index. Treatment with mangaba reduced the serum cholesterol by 18%, as well as the hepatic deposition of triacylglycerides by 26% and cholesterol by 25%, in addition to increasing bile acid synthesis by 77% in this organ. Mangaba powder consumption attenuated the degree of hepatic steatosis, reduced lipid peroxidation and increased the serum and hepatic antioxidant capacity in HFMG rats. These results show that the consumption of mangaba powder had lipid-lowering, hepatoprotective and antioxidant effects, especially in HFMG rats, which may be associated with an additive and synergistic action between the bioactive compounds present in the product. Full article
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